Ramelteon (TAK-375) CAS 196597-26-9 daahirnimo>99.5% (HPLC)
Soo saaraha iyo alaab-qeybiyaha hormuudka ah, Dhexdhexaadiyeyaasha Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-hal CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2- (2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com
| Magaca Kiimikada | Ramelteon |
| La mid ah | (S)-N-[2-(2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl) ethyl] propionamide;TAK-375;TAK375;TAK 375;Rozerem |
| Lambarka CAS | 196597-26-9 |
| Lambarka CAT | RF2885 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C16H21NO2 |
| Miisaanka Molecular | 259.35 |
| Meesha dhalaalaysa | 113.0 ilaa 116.0 ℃ |
| Barta Karsan | 455.3 ± 24.0 ℃ |
| Cufnaanta | 1.119±0.06 g/cm3 |
| Wareeg gaar ah [α]20/D | -55.0° ilaa -60.0° (C=1, CHCL3) |
| Ku milmay biyaha | Aan ku milmin Biyaha (11 mg/l 25 ℃) |
| Solubility | Ku milmay Ethanol, Methanol, DMSO |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada Crystalline White |
| Daahirnimada / Habka Falanqaynta | > 99.5% (HPLC) |
| Meesha dhalaalaysa | 113.0 ~ 116.0 ℃ |
| Khasaare xagga qalajinta | <0.50% |
| Hadhaaga dabka | <0.10% |
| Isomer Purity | <0.10% |
| Biraha culus | <10pm |
| Aysiidh ama Alkalinity | U hoggaansamo |
| Ethanol | <5000pm |
| Xumaanta Keliya | <0.20% |
| Wadarta wasakhda | <0.50% |
| Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | API, Loo Oggolaaday Daawaynta Hurdo La'aanta |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
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Hantidhawrka Warshada?Hantidhawrka warshada soo dhawoow.Fadlan horay u sii ballan.
MOQ?Ma jiro MOQ.Dalabka yar waa la aqbali karaa.
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Dukumentiyada?Adeegga iibka kadib: COA, MOA, ROS, MSDS, iwm waa la bixin karaa.
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Ramelteon (CAS: 196597-26-9) waxaa markii ugu horeysay ansixiyay Maamulka Cuntada iyo Dawooyinka ee Maraykanka (FDA) July 22, 2005, ka dibna waxaa ansixiyay Pharmaceuticals and Medical Agency (PMDA) Apr 16, 2010. Waa la sameeyay oo oo loo suuq geeyey sida Rozerem® by Takeda,waxaa loo isticmaali karaa in lagu daweeyo hurdo la'aanta iyadoo ay dhib ku tahay hurdo la'aan, waxayna saameyn sugan ku leedahay hurdo la'aan joogto ah iyo hurdo la'aan muddada gaaban ah.Alaabtani waxay si xushmad leh u dhaqaajin kartaa nooca 1 iyo nooca 2 reseptors ee melatonin (MT1, MT2), waxay kordhisaa hurdo gaaban oo hurdo ah (SWS) iyo hurdo dhaq-dhaqaaq isha oo degdeg ah (REW), taasoo hoos u dhigaysa hurdo la'aanta.Ramelteamide waa daawaynta hurdo la'aanta ee ugu horreysa ee aan la qabatimayn oo aan hoos iman koontarool gaar ah.Alaabtani waa agonist receptor melatonin.Waxay xiriir sare la leedahay melatonin MT1 iyo MT2 reseptors, waxayna ku leedahay saameyn gaar ah oo dhammaystiran oo agonistic ah oo ku saabsan MT1 iyo MT2 reseptors, laakiin lama falgala soo-dhoweeyaha MT3.Intaa waxaa dheer, kuma xirna neurotransmitter reseptors sida dhismayaasha GABA, oo aan faragelin hawlaha inta badan enzymes gudahood xad gaar ah.Sidaa darteed, waxay ka fogaan kartaa jahwareerka la xidhiidha daawooyinka GABA (taas oo keeni karta shilalka baabuurta, dhicista iyo jabka).iwm) iyo balwadda iyo ku-tiirsanaanta.Rozerem® waxa loo heli karaa kaniini ku dahaadhay filim si loogu isticmaalo afka, oo ka kooban 8 mg oo Ramelteon bilaash ah.Qiyaasta dadka waaweyn ee lagula taliyay waa 8 mg oo la qaato 30 daqiiqo gudahood markaad sariirta aado.
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Ramelteon (TAK-375) CAS 196597-26-9 daahirnimo>99....
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