Ramelteon Intermediate CAS 196597-78-1 daahirnimo>98.5% (HPLC)

Sharaxaad Gaaban:

Magaca: 1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-hal

La mid ah: 6,7-Dihydro-1H-Indeno[5,4-b]furan-8(2H) -hal

CAS: 196597-78-1

Daahirsanaanta:>98.5% (HPLC)

Muuqashada: Budada Adag ee Jaallaha ah ee Caddaan

Dhexdhexaadka Ramelteon (CAS: 196597-26-9)

Tayada Sare, Wax Soo Saarka Ganacsiga

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Sharaxaad:

Soo saaraha iyo alaab-qeybiyaha hormuudka ah, Dhexdhexaadiyeyaasha Ramelteon
Ramelteon (TAK-375) CAS 196597-26-9
2,3-Dihydrobenzofuran CAS 496-16-2
1,2,6,7-Tetrahydro-8H-Indeno[5,4-b]furan-8-hal CAS 196597-78-1
Ramelteon Acrylonitrile CAS 196597-79-2
Despropionyl Ramelteon Hydrochloride CAS 196597-80-5
2- (2,6,7,8-Tetrahydro-1H-Indeno[5,4-b]furan-8-yl)ethanamine Hydrochloride CAS 1053239-39-6
Please contact: alvin@ruifuchem.com

Guryaha Kiimikada:

Magaca Kiimikada	1,2,6,7-Tetrahydro-8H-indeno[5,4-b]furan-8-kow
La mid ah	6,7-Dihydro-1H-Indeno [5,4-b]furan-8 (2H) -hal;Ramelteon Dhexdhexaadiyaha 1;Ramelteon I
wasakhnimo	Ramelteon Impurity A
Lambarka CAS	196597-78-1
Lambarka CAT	RF2883
Heerka Saamiyada	Kaydka dhexdiisa, Awood Wax-soo-saar 20 Tan bishii
Qaanuunka molecular	C11H10O2
Miisaanka Molecular	174.20
Meesha dhalaalaysa	133.0 ilaa 137.0 ℃
Barta Karsan	334.2 ± 42.0 ℃
Cufnaanta	1.288± 0.06 g/cm3
Heerka khatarta	Xanaaqsan
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Budada Adag ee Jaallaha ah ee Cadaanka ah
Daahirnimada / Habka Falanqaynta	> 98.5% (HPLC)
Meesha dhalaalaysa	133.0 ilaa 137.0 ℃
Biyaha (waxaa qoray Karl Fischer)	<0.50%
Hadhaaga dabka	<0.10%
Wadarta wasakhda	<1.50%
1 H NMR Spectrum	Waafaqsan Qaab-dhismeedka
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	Dhexdhexaadka Ramelteon (CAS: 196597-26-9)

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Codsiga:

1,2,6,7-Tetrahydro-8H-indeno [5,4-b]furan-8-hal (CAS: 196597-78-1) waxaa loo isticmaalaa sidii dhexdhexaad ah ee Ramelteon (CAS: 196597-26-9) , xudunta hooyada ee synthesizing Ramelteon.Ramelteon waa kan ugu horreeya ee fasalka cusub ee wakiilada hurdada kuwaas oo si xushmad leh ugu xidha MT1 iyo MT2 reseptors ee nukleus suprachiasmatic (SCN), halkii ay ku xidhi lahaayeen kuwa qaata GABA.Ramelteon ma tusin wax la mahadin karo oo ku xidhan soo-qabayaasha GABAA, kuwaas oo la xidhiidha anxiolytic, myorelaxant, iyo saamaynta amnesic.Ramelteon waxaa loo isticmaali karaa hurdo la'aan, gaar ahaan hurdo la'aanta.Ramelteon laguma tusin in uu soo saaro ku-tiirsanaanta mana muujin wax awood ah oo lagu takri-falo, iyo ka-noqoshada iyo dib-u-soo-celinta hurdo-la'aanta ee caadiga ah ee modulators GABA kuma jiraan ramelteon.Dhakhaatiirta qaarkood waxay sidoo kale u isticmaalaan ramelteon daawaynta marxaladda hurdada oo daahday.Daawaynta hurdo la'aanta (dhibaatada hurdo la'aanta).Waxa kale oo loo isticmaali karaa xaalado kale sida uu go'aamiyo dhakhtarkaagu.Ramelteon waa agonist melatonin ah.Waxay u shaqeysaa iyada oo ku shaqeyneysa soo-dhoweynta melatonin ee maskaxda, taas oo kaa caawineysa inaad seexato.