Rapamycin Sirolimus RAPA CAS 53123-88-9 Assay ≥98.5% API Nadiifnimada Sare ee Warshada
Soo-saare leh Nadiif Sarreysa iyo Tayo Deggan
Magaca Kiimikada: Rapamycin;Sirolimus;RAPA
CAS: 53123-88-9
Wakiilka difaaca jirka ee macrolide
API Tayada Sare, Wax soo saarka Ganacsiga
Magaca Kiimikada | Rapamycin |
La mid ah | Sirolimus;RAPA;AY-22989 |
Lambarka CAS | 53123-88-9 |
Lambarka CAT | RF-API59 |
Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
Qaanuunka molecular | C51H79NO13 |
Miisaanka Molecular | 914.19 |
Meesha dhalaalaysa | 183.0 ~ 185.0 ℃ |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ama Banaan-cad budada Crystalline |
Aqoonsiga A | Baaxadda IR ee diyaarinta potassium bromide ee muunadda waxay muujinaysaa maxima dhererka hirarka la mid ah diyaarinta la midka ah ee heerka tixraaca guriga dhexdiisa. |
Aqoonsiga B | UV spectrum ee 95% ethanol diyaarinta muunadu waxay muujinaysaa maxima at 267nm, 277nm, 288nm sida diyaargarowga la midka ah ee heerka tixraaca guriga dhexdiisa. |
Aqoonsiga C | Waqtiga haynta ee meelaha ugu sarreeya ee trans-iyo cis-stereoisomers ee chromatogram-ka diyaarinta assay waxay u dhigantaa in chromatogram-ka diyaarinta caadiga ah, sida lagu helay baaritaanka |
Wareegga indhaha | -147.0°~ -157.0° |
Khasaare xagga qalajinta | ≤0.50% |
Hadhaaga dabka | ≤0.20% |
Biraha culus | ≤20pm |
Xumaanta Shaqsiga ah | ≤1.5% |
Wadarta wasakhda | ≤2.0% (marka laga reebo Cis-Stereoisomer of Sirolimus) |
Cis-Stereoisomer ee Sirolimus | ≤5.0% |
Xalalka Haraaga ah | |
Ethanol | ≤5000ppm |
Ethyl acetate | ≤5000ppm |
Cyclohexane | ≤5000ppm |
Acetone | ≤5000ppm |
Diethyl Ether | ≤5000ppm |
Qiimayn | ≥98.5% (la xisaabiyay trans- iyo cis-stereoisomer of sirolimus ku salaysan dired) |
Heerka Imtixaanka | Farmashiyaha Shiinaha (CP);Heerka Ganacsiga |
Isticmaalka | Walaxda Farmashiyeedka Firfircoon (API) |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
Rapamycin (Sirolimus; AY 22989) waa kicinta autophagy, nooc cusub oo ah wakiilka difaaca jirka ee macrolide oo leh saameyn daawaynta wanaagsan, suntan hoose, iyo nephrotoxicity.Waxaa loo isticmaali karaa in lagu ilaaliyo difaaca xubnaha taranka (gaar ahaan kuwa kelyaha lagu tallaalo) si loo yareeyo diidmada tallaalka ka dib qalliinnada xubnaha taranka.