Remdesivir Intermediate CAS 1354823-36-1 COVID-19 N-[(S)-(4-nitrophenoxy) phenoxyphosfinyl]-L-Alanine 2-ethylbutyl ester
Soo-saare Ganacsi Supply Remdesivir iyo Dhexdhexaadiyayaasha La Xiriira ee Tayada Sare leh
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Magaca Kiimikada | N-[(S)-(4-nitrophenoxy) phenoxyphosfinyl] -L-Alanine 2-ethylbutyl ester |
La mid ah | Remdesivir Intermediate;Remdesivir Side Side;Remdesivir p-NitroPhenoxy L-Alanine wasakh;Remdesivir wasakhnimada 4;Remdesivir-002;(S)-2-Ethylbutyl 2-(((S)-(4-nitrophenoxy)(phenoxy)-phosphoryl-amino) propanoate |
Lambarka CAS | 1354823-36-1 |
Lambarka CAT | RF-PI297 |
Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
Qaanuunka molecular | C21H27N2O7P |
Miisaanka Molecular | 450.42 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ilaa ku dhawaad cad budo |
Aqoonsiga | IR, HPLC |
Khasaare xagga qalajinta | ≤1.0% |
Xumaanta Keliya | ≤0.50% |
Biraha culus | ≤20pm |
daahirnimo | ≥98.0% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Remdesivir (CAS 1809249-37-3);COVID 19 |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka iyo cayayaanka.
N-[(S)-(4-nitrophenoxy) phenoxyphosphinyl]-L-Alanine 2-ethylbutyl ester (CAS 1354823-36-1, sidoo kale loo yaqaan Remdesivir Impurity 4) waa fosphoramidate sidechain sida caadiga ah loo isticmaalo diyaarinta Remdesivir (CAS) 1809249-37-3, GS-5734), oo ah dawo cusub oo ka hortag fayrus ah oo asal ahaan loogu talagalay daawaynta cudurka fayraska Ebola iyo caabuqyada fayraska Marburg ka dibna sidoo kale lagu helay inay muujiso firfircoonida fayraska ka dhanka ah coronaviruses (sida SARS-Cov-2/ Covid 19).Intii uu dillaacay cudurka cusub ee Coronavirus 2019 (COVID-19), Remdesivir (CAS 1809249-37-3) waa mid ka mid ah alaabada cilmi baarista ee COVID-19.Remdesivir, oo lagu iibiyo magaca sumadda Veklury, waa daawo fayruska ka hortagga ah oo ballaaran oo ay soo saartay shirkadda biopharmaceutical-ka ee Gilead Sciences.Waxa lagu duraa irbad xididka.Intii lagu jiray masiibada COVID-19, Remdesivir waa la oggolaaday ama loo oggolaaday isticmaalka degdegga ah si loogu daweeyo COVID-19 ilaa 50 waddan.Tilmaamaha la cusboonaysiiyay ee Ururka Caafimaadka Adduunka ee Noofambar 2020 waxa ka mid ah talobixin shuruudaysan oo ka dhan ah isticmaalka Remdesivir ee daawaynta COVID-19.