Rifamycin S CAS 13553-79-2 Nadiifinta>97.5% (HPLC) Warshada
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Magaca Kiimikada | Rifamycin S |
La mid ah | 1,4-Dideoxy-1,4-Dihydro-1,4-Dioxorifamycin;Rifaximin EP Impurity E |
Lambarka CAS | 13553-79-2 |
Lambarka CAT | RF-PI2058 |
Heerka Saamiyada | Kaydka dhexdiisa, Awoodda Wax-soo-saarka 500MT/Sannadka |
Qaanuunka molecular | C37H45NO12 |
Miisaanka Molecular | 695.76 |
Dareenka | Xasaasida kulaylka |
Wareeg gaar ah [α]20/D | +451.0°~+500.0° (C=0.1 gudaha MeOH) |
Meesha dhalaalaysa | 201℃ |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Jaalle ama Orange Jaalle Crystalline budada |
Khasaare xagga qalajinta | ≤3.00% (4saac 100 ℃) |
Hadhaaga dabka | ≤0.50% |
Walxaha laxidhiidha | |
Rifamycin-O | ≤0.50% |
Rifamycin-B | ≤0.50% |
Hal Peak | ≤1.00% |
Wadarta wasakhda | ≤2.50% |
Daahirnimada / Habka Falanqaynta | > 97.5% (HPLC) |
Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Nolosha shelf | 24 bilood laga bilaabo taariikhda wax soo saarka haddii si sax ah loo kaydiyo |
Isticmaalka | Dhexdhexaadiyaha Furaha ee Isku-dhafka Dawooyinka Rifamycin |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Rifamycin S (CAS: 13553-79-2) waa dhexdhexaadiye fure u ah isku dhafka daawooyinka rifamycin.Rifamycin S waa antibiyootig badh-synthetic ah.Rifamycin S waa quinone iyo antibiyootiko ka hortagga bakteeriyada Gram-positive (oo ay ku jirto MRSA).Rifamycin S waa foomamka oksaydhka ee nidaamka dhimista oksaydheynta-ka-soo-noqoshada leh ee ku lug leh laba electrons.Rifamycin S waxay abuurtaa noocyada ogsijiinta falcelinta (ROS) waxayna joojisaa peroxidation lipid microsomal.Rifamycin S waxa loo isticmaali karaa qaaxada iyo baraska.Rifamycin-yadu waa koox antibiyootik ah oo kiimiko la xidhiidha oo laga helay halsano dhaqamada Streptomycesmediterranei.Waxay ka tirsan yihiin nooc ka mid ah antibiyootiga loo yaqaan 'theansamycins' oo ka kooban giraanta makrocyclic ee isku xirtay laba boos oo aan isku xigan oo ah xudunta udgoonka.Rifamycins-yada iyo qaar badan oo ka mid ah soosaarkooda semisynthetic waxay xiiraan firfircooni ballaadhan oo ka hortag ah.Waxay si gaar ah ugu firfircoon yihiin bakteeriyada Gram-positive iyo M. qaaxada.Si kastaba ha ahaatee, waxay sidoo kale si firfircoon uga hortagaan bakteeriyada Gram-negative iyo fayrasyo badan.Rifampin, derivative asemisynthetic ee Rifamycin B, ayaa loo sii daayay sida wakiilka anantitubercular ee Maraykanka 1971. Derivative sekinemisynthetic, rifabutin, ayaa la ansixiyay 1992 si loogu daweeyo caabuqyada mycobacterial atypical.