Rivaroxaban CAS 366789-02-8 daahirnimo>99.5% (HPLC) Warshada API Tayada Sare
Soo saaraha soo saaraha ee Rivaroxaban Dhexdhexaadinta la xidhiidha:
(S)-(+)-Glycidyl Phthalimide CAS 161596-47-0
4-(4-Aminophenyl)morpholin-3-hal CAS 438056-69-0
Rivaroxaban Dhexdhexaadiyaha CAS 446292-07-5
5-Chlorothiophene-2-Carboxylic Acid CAS 24065-33-6
5-Chlorothiophene-2-Carbonyl Chloride CAS 42518-98-9
Rivaroxaban API CAS 366789-02-8
Magaca Kiimikada | Rivaroxaban |
La mid ah | (S)-Rivaroxaban;(S)-5-Chloro-N-(2-oxo-3-- (4- (3-oxomorpholino) phenyl) -oxazolidin-5-yl) methyl) thiophene-2-carbox;BAY 59-7939 |
Lambarka CAS | 366789-02-8 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C19H18ClN3O5S |
Miisaanka Molecular | 435.88 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada cad ama ku dhawaad cad |
Aqoonsiga A | Nuugista infrared ee Rivaroxaban waxay u dhigantaa heerarka tixraaca |
Aqoonsiga B | Waqtiga haynta ee ugu sarreeya ee xalka muunada waxay u dhigantaa tan nidaamka ku habboonaanta xalka, sida lagu helay nadiifnimada enantiomeric. |
Nadiifinta Enantiomeric | RVX RC01: ≤0.15% |
Qoyaanka (KF) | ≤0.50% |
Sulfated Ash | ≤0.10% |
Biraha culus | ≤20pm |
Acid acid | ≤5000ppm |
Walxaha La Xiriira (HPLC) | |
RVX RC02 | ≤0.15% |
RVX RC03 | ≤0.15% |
RVX RC04 | ≤0.15% |
RVX RC05 | ≤0.15% |
RVX RC06 | ≤0.15% |
RVX RC07 | ≤0.15% |
RVX RC08 | ≤0.15% |
Wax kasta oo kale oo aan nadiif ahayn | ≤0.10% |
Wadarta wasakhda | <0.50% |
Xalalka Hadhaaga ah (GC) | |
Ethanol | ≤5000ppm |
Toluene | ≤890pm |
Triethylamine | ≤320pm |
Daahirnimada / Habka Falanqaynta | > 99.5% (HPLC) (oo ku salaysan anhydrous) |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API;Dawooyinka Antithrombotic;FXa inhibitor |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
Rivaroxaban(CAS:366789-02-8) (Xarelto, Bayer) waa daawada xinjirowga lidka ku ah afka.Waa arrin toos ah oo afka ah oo firfircoon Xa inhibitor.Rivaroxaban waxaa loogu talagalay 'daawaynta xinjirowga xididdada qotodheer iyo sambabada sambabada, iyo ka hortagga xinjirowga qotodheer ee soo noqnoqda iyo sambabada sambabada ee dadka waaweyn'.Daawaynta bilawga ah ee sambabada degdega ah, qiyaasta lagu taliyey ee rivaroxaban waa 15 mg laba jeer maalintii 21 ka maalmood ee ugu horreeya oo ay ku xigto 20 mg hal mar maalintii daaweynta joogtada ah iyo ka hortagga xinjirowga xididada soo noqnoqda.Fibrillation-ka aan Valvular Atrial Fibrillation (NVAF) si looga hortago istaroogga & embolism-ka habdhiska.Daawaynta degdega ah ee VTE & ka hortagga VTE ee soo noqnoqdaKahortagga dhacdooyinka xinjirowga dhiigga xididada (VTE) ee wadarta guud ee miskaha ama qalliinka beddelka jilibka (THR, TKR).