Roflumilast CAS 162401-32-3 Assay 99.0~101.0% API

Sharaxaad Gaaban:

Magaca Kiimikada: Roflumilast

CAS: 162401-32-3

Qiimaynta: 99.0 ~ 101.0%

Muuqashada: Caddaan ama Ku dhawaad White Budada Crystalline

API PDE-4 Inhibitor COPD

Xiriirka: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

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Sharaxaad:

Qalabka Kiimikada ee Ruifu Roflumilast Dhexdhexaadinta:
Roflumilast CAS 162401-32-3
4-Amino-3,5-Dichloropyridine CAS 22889-78-7

Guryaha Kiimikada:

Magaca Kiimikada	Roflumilast
La mid ah	3-(Cyclopropylmethoxy)-N-(3,5-Dichloropyridin-4-yl)-4-(Ddifluoromethoxy) Benzamide
Lambarka CAS	162401-32-3
Lambarka CAT	RF-PI2075
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C17H14Cl2F2N2O3
Miisaanka Molecular	403.21
Cufnaanta	1.471 ± 0.060 g / cm3
Dareenka	Xasaasida kulaylka
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Caddaan ama ku dhawaad cad budada crystalline
Solubility	Ku milmayn bilaashka ah ee acetone, si yar ugu milmay acetronitrile, wax yar oo aan lagu milmi karin ethanol anhydrous, ficil ahaan aan lagu milmi karin biyaha
Meesha dhalaalaysa	157.0 ~ 162.0 ℃
Khasaare xagga qalajinta	<0.50%
Hadhaaga dabka	≤0.10%
Biraha culus	≤10pm
Chloride	≤0.01%
Aqoonsiga A. UV	Dhererka hirarka nuugista ugu badan waa inuu ahaadaa 213 ~ 251nm
Aqoonsiga B. IR	Qiyaasta nuugista IR ee muunada waxay u dhigantaa tan tixraaca
Aqoonsiga C.	Waxay muujinaysaa falcelinta fluoride
Walxaha laxidhiidha
Xumaanta Keliya	≤0.10%
Wadarta wasakhda	<0.50%
Xalalka Haraaga ah
Tert-Butanol	<0.10%
Tetrahydrofuran	<0.072%
Toluene	<0.089%
N, N-Dimethylformamide	<0.088%
Qiimayn	99.0 ~ 101.0% (waxaa lagu xisaabiyay ku salaysan qalalan)
Heerka Imtixaanka	Heerka Ganacsiga
Isticmaalka	API;COPD

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka

Faa'iidooyinka:

FAQ:

Codsiga:

Roflumilast (CAS: 162401-32-3) waa fosfodiesterase-4 (PDE-4) inhibitor ah oo afka laga doorto iyo xarun benzamide ah.Waxaa soo saartay shirkadda Jarmalka ee Altana 1993-kii waana kan keliya ee afka laga qaato ee PDE-4 inhibitor loo isticmaalo in lagu daweeyo cudurrada mareenka neef-mareenka ee loo oggolaaday iib.Roflumilast waa daawadii ugu horeysay ee nooceeda ah ee lagu bartilmaansado cudurka sambabada ee joogtada ah ee daran (COPD), sidoo kale waa daawadii ugu horeysay ee ka hortagga caabuqa afka ee si gaar ah loogu sameeyo bukaanada COPD.Hantideeda gaarka ah waxay gacan ka geysan kartaa nidaaminta COPD: marka lagu daro bronchodilators si loogu daweeyo bukaannada COPD ee aadka u daran, Roflumilast waxay yeelan kartaa faa'iido ah inay sii yareyso calaamadaha iyo heerka sii xumaanaya, sidaas darteed waxay ka dhigaysaa daawada ugu horreysa ee bartilmaameedka ah bukaanada qaba COPD phenotype-spAecific COPD soo noqnoqda. iyo xannibaad ba'an oo socodka hawada ee la xidhiidha qufac daba-dheeraada iyo xaakada xad-dhaafka ah.Ka sokow daawaynta COPD daran, Roflumilast waxa kale oo loo isticmaali karaa ka hortagga iyo daawaynta cudurrada mareenka neef-mareenka xoolaha, boronkiitada xuubka xad-dhaafka ah, boronkiitada neefta, iyo boronkiitada ba'an iyo sacculitis hawada oo ay weheliso dheecaan aan caadi ahayn oo neef-mareenka.