Sitagliptin CAS 486460-32-6 Nadiifinta>99.0% (HPLC) API Nadaafadda Sare ee Warshada
Bixinta Sitagliptin Phosphate Monohydrate Dhexdhexaadiyaha La Xiriira:
Sitagliptin API CAS 486460-32-6
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Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
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Sitagliptin Fosfate Monohydrate Dhexdhexaad CAS 486460-21-3
| Magaca Kiimikada | Sitagliptin |
| La mid ah | (3R) -3-Amino-1-[3- (trifluoromethyl) -5,6,7,8-tetrahydro-1,2,4-triazolo[4,3-a] pyrazin-7-yl]-4- (2,4,5-trifluorophenyl) butan-1-kow |
| Lambarka CAS | 486460-32-6 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C16H15F6N5O |
| Miisaanka Molecular | 407.31 |
| Meesha dhalaalaysa | 114.0 ~ 115.0 ℃ |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada Crystalline ee Caddaan iyo Off-White |
| Aqoonsiga HPLC | Wakhtiga Haynta ee Muunadu waa mid waafaqsan heerka tixraaca |
| Khasaare xagga qalajinta | <1.0% |
| Hadhaaga dabka | <0.20% |
| Walxaha laxidhiidha | |
| Xumaan Keli ah | <0.50% |
| Wadarta wasakhda | <1.0% |
| daahirnimo | >99.0% (HPLC) |
| Nadiifinta Enantiomeric | <0.50% |
| Biraha culus | <20ppm |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | API;Nooca II ee Sonkorowga Mellitus |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
Sitagliptin (CAS: 486460-32-6), oo ah nooc cusub oo ah dawada ka hortagga sonkorowga, Sitagliptin Phosphate waxay leedahay faa'iidooyinka ku-tiirsanaanta gulukooska, saamaynta hypoglycemic dhexdhexaad ah, dheecaan kordhay oo aan lahayn hypoglycemia, waxay si wax ku ool ah u yaraysay gaajada, mana lahayn waxyeellooyin sida lallabbo. matag, barar iyo miisaanka jidhka oo kordha.Sitagliptin phosphate sida daawaynta kaliya ee bukaanada qaba nooca II ee sonkorowga waxay si weyn u dhimi kartaa heerka hemoglobin glycosylated (HbA1c).Waa dipeptidyl peptidase-4 (DPP-4) inhibitor, kaas oo hagaajin kara awoodda jidhka bini'aadamka si loo yareeyo heerka sonkorta dhiigga ee sarreeya.Sitagliptin waxaa soo saaray Merck & Co. waxaana loo ogolaaday isticmaalka caafimaadka gudaha Mareykanka 2006.
