Telmisartan CAS 144701-48-4 Nadiifinta>99.5% (HPLC) Sawirka Warshada API

Telmisartan CAS 144701-48-4 Nadiifinta>99.5% (HPLC) Warshada API

Sharaxaad Gaaban:

Magaca Kiimikada: Telmisartan

CAS: 144701-48-4

Daahirsanaanta:>99.5% (HPLC)

Muuqashada: Crystalline cad ama Off-White

Angiotensin II Receptor antagonist

Tayada Sare, Wax Soo Saarka Ganacsiga

E-Mail: alvin@ruifuchem.com

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Faahfaahinta Alaabta

Alaabooyinka La Xiriira

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Sharaxaad:

Bixinta Kiimikada Ruifu ee Telmisartan Dhexdhexaadinta oo leh nadiif sare
Telmisartan CAS 144701-48-4
Methyl 2-(p-Tolyl) benzoate CAS 114772-34-8
2- (p-Tolyl) benzoic Acid CAS 7148-03-0
Telmisartan Benzimidazole Acid CAS 152628-03-0
Telmisartan Methyl Ester CAS 528560-93-2
Methyl 2-[4- (Bromomethyl) phenyl] benzoate CAS 114772-38-2
Methyl 4-(Butyrylamino)-3-Methyl-5-Nitrobenzoate CAS 152628-01-8
2-n-Propyl-4-Methyl-6-(1-Methylbenzimidazole-2-yl)benzimidazole CAS 152628-02-9

Guryaha Kiimikada:

Magaca Kiimikada	Telmisartan
La mid ah	4'-[[4-Methyl-6-(1-Methyl-1H-Benzimidazol-2-yl)-2-Propyl-1H-Benzimidazol-1-yl]methyl]biphenyl-2-Carboxylic Acid;4'-[(1,4'-Dimethyl-2'-propyl[2,6'-bi-1H-Benzimidazol]-1'-yl)methyl]-[1,1'-Biphenyl]-2-Carboxylic Acid
Lambarka CAS	144701-48-4
Heerka Saamiyada	Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan
Qaanuunka molecular	C33H30N4O2
Miisaanka Molecular	514.63
Meesha dhalaalaysa	261.0 ~ 263.0 ℃
Summada	Kiimikada Ruifu

Tilmaamaha:

Shayga	Tilmaamaha
Muuqashada	Caddaan ama Banaan-cad budada Crystalline
ur	Sifada
Solubility	Si Xoogan Ugu Soluble Methylene Chloride, In Yar Souble Methanol, Qayb ahaan Aan Biyo Ku milmin, Ku Mila 1M Xalka Hydroxide
Aqoonsiga IR	Waa in uu la jaanqaadaa Nuugista Infrared-ka ee RS
Aqoonsiga HPLC	Waqtiga Haysashada ee ugu sarreysa waa inuu la mid yahay RS
Daahirnimada / Habka Falanqaynta	> 99.5% (HPLC)
Khasaare xagga qalajinta	<1.00%
Hadhaaga dabka	<0.10%
Walxaha laxidhiidha
Isku dhafka Telmisartan ee La Xiriira A	<0.10%
Telmisartan Amide	<0.10%
Telmisartan La Xiriira Isku-dhafka B	<0.10%
Telmisartan Diacid	<0.10%
Telmisartan Tert-Butyl Ester	<0.20%
Telmisartan aan la garanayn wasakh	<0.20%
Xumaan aan la cayimin	<0.10%
Wadarta wasakhda	<1.00%
Xalalka Haraaga ah
Methanol	<0.30%
Ethanol	<0.50%
Methylene Dichloride	<0.06%
n-Hexane	<0.029%
Acid Acid Ethyl Ester	<0.50%
Toluene	<0.089%
Acid acid	<0.50%
Biraha culus	<10pm
Arsenic (As)	<1.00pm
Ledhka (Pb)	<1.00pm
Cadmium (Cd)	<1.00pm
Cabbirka Qaybaha	D90 Aan Ka Badnayn 15μm
Cufnaanta Bulk (g/cc)	0.11-0.20
Cufnaanta la taabtay (g/cc)	0.22-0.30
Hadhaaga sunta cayayaanka	xun
Wadarta tirada saxanada	<1000cfu/g
Khamiirka & Caaryada	<100cfu/g
E. Coli	xun
Salmonella	xun
Heerka Imtixaanka	Heerka Ganacsiga;USP 41 Heerka
Isticmaalka	API

Xidhmada & Kaydinta:

Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka

Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka

Faa'iidooyinka:

FAQ:

Codsiga:

Telmisartan (CAS: 144701-48-4) waa derivative benzimidazole iyo antagonist aan peptide ahayn angiotensin II leh hanti dhiig-karka.Telmisartan waxay si xushmad leh uga soo horjeedaa angiotensin II oo ku xidhan AT1 nooc-hoosaadka soo-dhoweeyaha, oo ku yaal muruqa siman ee xididdada dhiigga iyo qanjidhada adrenal.Antagonism-ku wuxuu keenaa vasodilation wuxuuna xannibaa soosaarka aldosterone ee dhexdhexaadinta angiotensin II, taas oo keenta hoos u dhaca soodhiyamka iyo biyaha iyo sidoo kale korodhka qashin-saarka potassium taasoo horseedaysa hoos u dhac ku yimaada cadaadiska dhiigga.Telmisartan waa nooc cusub oo ah dawooyinka cadaadiska dhiigga, waxaa loo isticmaalaa kaligiis ama lagu daro noocyada kale ee antihypertensives ee daawaynta dhiigkarka.Telmisartan waxaa markii hore sameeyay shirkadda dawooyinka ee Jarmalka Boehringer Ingelheim;waxay kasbatay shatiga Jarmalka EP502,314 sanadkii 1991, markii ugu horaysay ee la ansixiyay inay soo gasho suuqa Maraykanka November 1998, ka dibna waxay gashay Jarmalka, Filibiin, Australia, Belgium, British, iyo suuqyo kale.