Tenofovir CAS 147127-20-6 Assay 98.0%~102.0% API Warshada La-dagaalanka HIV
Qaybinta Ganacsiga ee Tenofovir Dhexdhexaadiyeyaasha la xidhiidha:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl) fosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl) adenine CAS 14047-28-0
Diethyl (Hydroxymethyl) fosfonate CAS 3084-40-0
Adenine CAS 73-24-5
Magaca | Tenofovir |
La mid ah | (R)-PMPA;(R)-9-(2-Phosphonomethoxypropyl) Adenine |
Lambarka CAS | 147127-20-6 |
Lambarka CAT | RF-API07 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C9H14N5O4P |
Miisaanka Molecular | 287.22 |
Meesha dhalaalaysa | 276.0-280.0 ℃ |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ama ku dhawaad cad budada crystalline |
Habka Qiimaynta / Falanqaynta | 98.0% ~ 102.0% (ku salaysan anhydrous) |
Solubility | In yar oo Biyo ah (0.1g in 100ml);Dhaqan ahaan Aan ku milmin Methanol (0.01g 100ml iyo in ka badan) |
Aqoonsiga UV | Nuugista qiyaastii 261nm |
Aqoonsiga HPLC | Wakhtiga haynta ee ugu sarraysa maamulaha ee muunadda imtixaanku waa inuu la mid yahay kan caadiga ah |
Sulfate Ash | ≤1.5% |
Biyaha (KF) | ≤3.0% |
Wareegga indhaha ee gaarka ah | -19.0° ~ -23.0° (oo ah 25℃ ku salaysan anhydrous) |
PMPA Monoester wasakh | ≤1.5% (HPLC) |
Mid Kasta oo Xumaan Xun | ≤0.5% (HPLC) |
Wadarta wasakhda | ≤3.0% (HPLC) |
Nadiifinta Enantiomeric | ≤0.5% (HPLC) |
9-Propenyl Adenine | ≤75ppm (HPLC) |
Heerka Imtixaanka | Heerka Ganacsiga |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg/ durbaan kartoon, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka.
Tenofovir (CAS: 147127-20-6) waa acyclic phosphonate nucleotide analoue iyo reverse-transcriptase inhibitor (NtRTI).Waxa loo isticmaalaa sidii wakiilka ka hortagga HIV.Ka hortagga fayraska.Tenofovir disoproxil (Viread) waa analoogga nucleotide ee ugu horreeya ee ay ansixisay FDA Mareykanka si loogu daweeyo caabuqyada HIV-1.Tenofovir waa daawo loo isticmaalo daawaynta cagaarshow B raaga iyo sidoo kale ka hortagga iyo daawaynta HIV/AIDS.Waxay joojisaa dhaqdhaqaaqa HIV-ga beddelka transcriptase iyada oo la tartamaysa substrate-ka dabiiciga ah ee deoxyadenosine 5'-triphosphate, taasoo keenaysa joojinta silsiladda DNA-da.