Tenofovir Disoproxil Fumarate CAS 202138-50-9 Assay 98.0%~102.0% API Warshada
Qaybinta Ganacsiga ee Tenofovir Dhexdhexaadiyeyaasha la xidhiidha:
Tenofovir CAS: 147127-20-6
Tenofovir Disoproxil Fumarate CAS 202138-50-9
Tenofovir Alafenamide Hemifumarate CAS 1392275-56-7
Chloromethyl isopropyl Carbonate CAS 35180-01-9
Diethyl (p-Toluenesulfonyloxymethyl) fosphonate CAS 31618-90-3
(R)-(+)-Propylene Carbonate CAS 16606-55-6
(R)-9-(2-Hydroxypropyl) adenine CAS 14047-28-0
Diethyl (Hydroxymethyl) fosfonate CAS 3084-40-0
Adenine CAS 73-24-5
Magaca Kiimikada | Tenofovir Disoproxil Fumarate |
La mid ah | Tenofovir DF;Bis(POC)-PMPA Fumarate;GS 4331 Fumarate |
Lambarka CAS | 202138-50-9 |
Lambarka CAT | RF-API106 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C23H34N5O14P |
Miisaanka Molecular | 635.52 |
Meesha dhalaalaysa | 113.0 ilaa 115.0 ℃ |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada cad ama ku dhawaad cad |
Aqoonsiga A | IR Spectrum wuxuu waafaqsan yahay heerka tixraaca |
Aqoonsiga B | Wakhtiga haynta ee ugu sarraysa ee xalka muunada waxay u dhigantaa tan xalka caadiga ah, sida lagu helay tijaabada |
Qiimayn | 98.0% ~ 102.0% (ku salaysan anhydrous) |
Biyo | ≤1.0% |
Fumaric acid | 17.5% ~ 19.0% |
Hadhaaga dabka | ≤0.20% |
Biraha culus | ≤20pm |
Chloromethyl isopropyl Carbonate | ≤0.15% |
Walxaha laxidhiidha | |
Tenofovir | ≤0.15% |
Adenine | ≤0.15% |
Tenofovir Isoproxi Monoester | ≤1.0% |
Tenofovir Disoproxil Ethyl Ester | ≤0.15% |
Tenofovir Isopropyl Isoproxil | ≤0.30% |
Tenofovir Disoproxil Carbamate | ≤0.15% |
Tenofovir Disproxil | ≤0.15% |
Xumaan Keli ah | ≤0.10% |
Wadarta wasakhda | ≤2.0% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | API |
Xidhmada: Dhalo, bacda bireed ee aluminium, 25kg/Drum kartoonada, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka.
Tenofovir Disoproxil Fumarate (CAS: 202138-50-9), dawada tenofovir (Magaca Ganacsiga: Viread) ee ay soo saartay Sayniska Gilecaad, waa nooc ka mid ah daawooyinka nucleotide-analogues antiretroviral, oo saameyn ku leh iyada oo u dhaqmaysa sidii dib-u-celinta transcriptase inhibitors[nRTIs] , kaas oo xannibaya reverse transcriptase, enzyme muhiim u ah wax soo saarka fayraska ee dadka qaba HIV.Waa in la ogaadaa inay tahay xannibaadaha dib-u-celinta nucleotide-ka ee abid loo isticmaalo daaweynta caabuqa HIV.Tenofovir Disoproxil Fumarate waxa loo beddelaa tenofovir in vivo, kaas oo ah acyclic nucleoside phosphonate [nucleotide] analooga adenosine 5'-monophosphate.Guud ahaan waxaa lagu daraa noocyada kale ee daawada.Daawooyinka HIV-ga ma daawayn karaan HIV/AIDS, laakiin qaadashada daawooyinka isku-darka ah ee HIV-ga [oo loo yaqaanno nidaamka HIV] maalin kasta waxay ka caawin kartaa dadka qaba HIV inay nolol dheer helaan, nolol caafimaad leh.Iyada oo ku saleysan dukumeentiga FDA, tenofovir disoproxil fumarate wuxuu sidoo kale noqon karaa daawaynta fayraska cagaarshow B ee raaga [HBV] ee dadka waaweyn iyo carruurta 12 sano jir iyo ka weyn.