tert-Butyl 2-(4- (pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7 Atazanavir Intermediate
Soo saaraha soo saaraha Atazanavir Dhexdhexaadiyeyaasha la xidhiidha
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tert-Butyl 2-(4-(pyridin-2-yl)benzyl)hydrazinecarboxylate CAS 198904-85-7
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Magaca Kiimikada | tert-Butyl 2-(4-(pyridin-2-yl) benzyl) hydrazinecarboxylate |
La mid ah | 1-Boc-2-[4-(2-pyridinyl)benzylidene]hydrazine |
Lambarka CAS | 198904-85-7 |
Lambarka CAT | RF-PI381 |
Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
Qaanuunka molecular | C17H21N3O2 |
Miisaanka Molecular | 299.37 |
Meesha dhalaalaysa | 74.0 ~ 77.0 ℃ |
Cufnaanta | 1.117 ± 0.06 g / cm3 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Caddaan ilaa qafiif ah budada jaalaha ah |
Khasaare xagga qalajinta | ≤0.50% |
daahirnimo | ≥98.0% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexdhexaadiyaha Atazanavir |
Xidhmada: Dhalo, Bac aluminium biil ah, Durbaan kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka.
tert-Butyl 2- (4- (pyridin-2-yl) benzyl) hydrazinecarboxylate (CAS: 98904-85-7) waa dhexdhexaad ah oo la soo saaray inta lagu guda jiro soo saarista fayraska protease inhibitors.Waa dhexe ee Atazanavir.Atazanavir waa ka hortagga HIV-1 protease (EC50=2.6 nM).Unugyada go'doonsan, waxay leedahay wax lagu daro saamaynta fayraska dhexdhexaadka ah ee dhexdhexaadka ah marka lagu daro dawooyinka kale ee ka hortagga retroviral.Natiijo ahaan, waxaa caadi ahaan loo isticmaalaa in vivo daawaynta isku dhafan ee caabuqa HIV-1.