tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7 daahirnimo>98.0% (HPLC) Warshada Dhexe ee Palbociclib
Qalabka Kiimikada ee Ruifu Palbociclib Dhexdhexaadiyaha La Xiriira:
Palbociclib CAS 571190-30-2
5-Bromo-2,4-Dichloropyrimidine CAS 36082-50-5
5-Bromo-2-Chloro-N-Cyclopentylpyrimidin-4-Amine CAS 733039-20-8
tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate CAS 571189-16-7
tert-Butyl 4-(6-Amino-3-Pyridyl)piperazine-1-Carboxylate CAS 571188-59-5
6-Bromo-2-Chloro-8-Cyclopentyl-5-Methylpyrido-[2,3-d]pyrimidin-7(8H) -hal CAS 1016636-76-2
2-Chloro-8-Cyclopentyl-5-Methyl-8H-Pyrido[2,3-d]pyrimidin-7-hal CAS 1013916-37-4
Magaca Kiimikada | tert-Butyl 4-(6-Nitropyridin-3-yl)piperazine-1-Carboxylate |
La mid ah | 1-Boc-4-(6-Nitro-3-Pyridyl)piperazine;4-(6-Nitro-3-pyridinyl)-1-Piperazinecarboxylic Acid tert-Butyl Ester;tert-Butyl 4-(6-Nitro-3-Pyridinyl)-1-Piperazinecarboxylate |
Lambarka CAS | 571189-16-7 |
Lambarka CAT | RF-PI1850 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C14H20N4O4 |
Miisaanka Molecular | 308.33 |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Bunni khafiif ah ilaa budada Brown |
Daahirnimada / Habka Falanqaynta | >98.0% (HPLC) |
LCMS | Waafaqsan Qaab-dhismeedka |
Khasaare xagga qalajinta | <1.00% |
Wadarta wasakhda | <2.00% |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Dhexe ee Palbociclib (CAS: 571190-30-2) |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
tert-Butyl 4- (6-nitropyridin-3-yl) piperazine-1-carboxylate (CAS: 571189-16-7) waa dhexe ee Palbociclib (CAS: 571190-30-2).Palbociclib (sidoo kale loo yaqaan lambarka isku dhafka PD-0332991) waa daawo tijaabo ah oo loogu talagalay daawaynta kansarka naasaha oo ay samaysay Pfizer.Waa xakameyn door ah oo ka mid ah kinase-ku-tiirsanaanta cyclin CDK4 iyo CDK6.Palbociclib wuxuu xannibaa horumarka wareegga unugga ee wajiga G1 una gudbaya S isagoo xannibaya CDK4/6-ku-tiirsanaanta retinoblastoma (RB) fosforyaalka.Palbociclibhas waxa loo isticmaalay daawaynta HER2 taban, receptor estrogen (ER) kansarka naaska metastatic togan.