Thiamphenicol CAS 15318-45-3 daahirnimo>99.5% (HPLC) Warshada
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Magaca Kiimikada | Thiamphenicol |
La mid ah | D-Thiophenikol;2,2-Dichloro-N-[(1R,2R) -1,3-Dihydroxy-1-[4- (Methylsulfonyl) phenyl] -2-propyl] acetamide;D-Threo-2,2-Dichloro-N-(β-Hydroxy-α-[Hydroxymethyl]-4-[Methylsulfonyl] phenethyl) acetamide |
Lambarka CAS | 15318-45-3 |
Lambarka CAT | RF-PI2043 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C12H15Cl2NO5S |
Miisaanka Molecular | 356.22 |
Solubility | Ku milma acetonitrile ama DMF.In yar oo Biyo ah |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada Crystalline White |
Meesha dhalaalaysa | 163.0 ~ 167.0 ℃ |
Wareeg gaar ah [α]20/D | -21.0°~-24.0° (C=5 gudaha DMF) |
Khasaare xagga qalajinta | <0.50% |
Hadhaaga dabka | <0.20% |
Walxaha laxidhiidha | |
Xumaan Keli ah | <0.50% |
Wadarta wasakhda | <1.00% |
Chlorides (Cl) | ≤0.02% |
Biraha culus | ≤10pm |
Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) |
Infrared Spectrum | Waafaqsan Qaab-dhismeedka |
Proton NMR Spectrum | Waafaqsan Qaab-dhismeedka |
Heerka Imtixaanka | Heerka Ganacsiga |
Isticmaalka | Broad Spectrum Antimicrobials;Daawooyinka Daawada Xoolaha |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Thiamphenicol (CAS: 15318-45-3) waa chloramphenicol antibiyootiko ah oo ballaaran.Waxay leedahay qaab-dhismeedka kiimikaad ee la mid ah chloramphenicol.methyl sulfone waxay bedeshay nitro of chloramphenicol, taas oo yaraysay sunteeda, iyo in vivo hawsheeda bakteeriyada waxay 2.5-5 jeer ka xoog badan tahay chloramphenicol.Bakteeriyada garaam-positive, sida streptococcus pneumoniae iyo hemolytic streptococcus, waxay leedahay saamayn bakteeriyada aad u xoog badan, halka bakteeriyada garaam-negative, sida Neisseria jabtada, meningococcus, Bacteroides sambabada, E. coli, Vibrio cholerae, Shigella. waxa kale oo ay leedahay saamayn bakteeriyada xooggan.Bakteeriyada anaerobic-ka, Rickettsia iyo amoeba, waxay saamayn bakteeriyada ku leedahay ilaa xad.Waxay leedahay hab isku mid ah antimicrobial leh chloramphenicol, taas oo inta badan joojisa isku-darka borotiinka bakteeriyada.Daawadan waxaa si dhakhso ah u nuugaya maamulka afka, kaas oo gaaraya heerka ugu sarreeya ee dhiigga laba saacadood gudahood.Nolosheeda kala badh waa 5 saacadood, taas oo ka badan chloramphenicol.Bakteeriyadu waxay leedahay iska caabin dhammaystiran oo iskutallaab ah iyo chloramphenicol, halka bakteeriyadu ay leedahay wax iska caabin ah oo u leh iyada iyo tetracycline.Thiamphenicol waa walax antimicrobial loogu talagalay daaweynta cudurrada faafa ee lo'da, doofaarka iyo digaagga.Waxa loo istcimaalayaa sida biyaha milmi kara ee thiamphenicol glycine hydrochloride ee daawaynta waalidnimada iyo horudhac ka kooban saldhiga thiamphenicol iyo istaarijka galleyda, (4:1) ama qaseeyaha kale, isticmaalka afka.Thiamphenicol waa antibiyootiko.Waa analoogga methyl-sulfonyl ee chloramphenicol waxayna leedahay dhaqdhaqaaq la mid ah, laakiin waa 2.5 ilaa 5 jeer.Sida chloramphenicol, waa mid aan lagu milmi karin biyaha, laakiin aad bay ugu milmaan xuubka.Waddamo badan ayaa looga isticmaalaa antibiyootiga xoolaha, laakiin waxa laga heli karaa Shiinaha, Marooko iyo Talyaaniga si loogu isticmaalo dadka.Inta badan digaagga, shinbiraha, cirridka cirridka, enteritis, jiidida saxaro jaale-cad, airsacculitis, peritonitis, perihepatitis, salpingitis, vitelline peritonitis, qallafsanaanta follicle, xabka xiidmaha oo ciriiri ah iyo dhiigbax, mesentery wuxuu u muuqdaa granuloma oo ay weheliso neefsasho adag iyo calaamado kale oo ay sababto refractory E.coli, pasteurella anatipestifer, salmone, iwm.Xoolaha iyo digaaga cudur ba'an ama dabadheeraad ah oo xagga neef-mareenka ah, qufac, sanka oo diif ah.Sidoo kale waxay saameyn wanaagsan ku leeyihiin E.coliilness, salmonella, epirythrozoonosis, cudurada staphylococci, daacuunka shimbiraha, necrotizing enterocolitis iyo cudurrada kale ee bakteeriyada.