Tolvaptan CAS 150683-30-0 API Nadiifnimo>99.0% (HPLC)
Soo saaraha soo saaraha Tolvaptan iyo Dhexdhexaadiyayaasha la xidhiidha:
Tolvaptan CAS 150683-30-0
7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-hal CAS 160129-45-3
o-Toluoyl Chloride CAS 933-88-0
4-Amino-2-Methylbenzoic Acid CAS 2486-75-1
2-Methyl-4-Nitrobenzoic Acid CAS 1975-51-5
| Magaca | Tolvaptan |
| Magaca Kiimikada | N-[4-(9-chloro-6-hydroxy-2-azabicyclo[5.4.0]undeca-8,10,12-triene-2-carbonyl)-3-methyl-phenyl]-2-methyl-benzamide |
| Lambarka CAS | 150683-30-0 |
| Lambarka CAT | RF-API101 |
| Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
| Qaanuunka molecular | C26H25ClN2O3 |
| Miisaanka Molecular | 448.94 |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Budada Crystalline ee Caddaan iyo Off-White |
| Hababka Aqoonsiga | IR, HPLC |
| Solubility | Ku milmay alkolada Benzyl iyo methanol laakiin si dhab ah ugu milmi karin biyaha iyo Hexane |
| Daahirnimada / Habka Falanqaynta | >99.0% (HPLC) |
| Meesha dhalaalaysa | 219.0 ~ 222.0 ℃ |
| Khasaare xagga qalajinta | <0.50% |
| Hadhaaga dabka | <0.10% |
| Xumaanta Keliya | <0.50% |
| Wadarta wasakhda | <1.00% |
| Biraha culus | ≤20pm |
| Xalalka Haraaga ah | La kulan Tilmaamaha |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | API;Dhexdhexaadiyeyaasha Daawooyinka |
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Tolvaptan (CAS: 150683-30-0), oo sidoo kale loo yaqaan OPC-41061, waa doorasho, tartan arginine vasopressin receptor 2 antagonist loo isticmaalo in lagu daaweeyo hyponatremia (heerka soodhiyamka dhiigga oo hooseeya) oo la xidhiidha wadnaha wadnaha oo aan shaqeynin, cirrhosis, iyo cilladda hormoonka antidiuretic ee aan habboonayn (SIADH).Otsuka Pharmaceutical tolvaptan oo shati u haysta magaca ganacsiga Samsca ka dib markii FDA ay ansixisay dawada bishii Maajo 2009. Tolvaptan ayaa sidoo kale muujisay waxtarka ka hortagga cudurka kelyaha ee polycystic.Tijaabadii 2004-tii, tolvaptan oo lagu maamulay dawooyinka dhaqameed ayaa lagu xusay inay kordhiso soo saarista dareeraha xad-dhaafka ah iyo inay hagaajiso heerarka soodhiyamka dhiigga ee bukaannada qaba wadnaha oo aan shaqaynayn iyada oo aan soo saarin waxyeellooyin sida hypotension (cadaadis dhiig oo hooseeya) ama hypokalemia (hoos u dhaca heerarka dhiigga ee potassium).Daawadu sidoo kale wax saameyn xun kuma yeelan shaqada kelyaha.
![7-Chloro-1,2,3,4-tetrahydrobenzo[b]azepin-5-hal CAS 160129-45-3 Tolvaptan Intermediate](https://www.ruifuchemical.com/uploads/7-Chloro-1234-tetrahydrobenzobazepin-5-one-CAS-160129-45-3-300x300.jpg)
