Valsartan CAS 137862-53-4 Assay 98.0~102.0% API
Soo saaraha soo saaraha Valsartan iyo Dhexdhexaadiyayaasha la xidhiidha:
Valsartan CAS: 137862-53-4
L-Valine Methyl Ester Hydrochloride (H-Val-OMe·HCl) CAS: 6306-52-1
Magaca Kiimikada | Valsartan |
La mid ah | N-Valeryl-N-[2'-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine |
Lambarka CAS | 137862-53-4 |
Lambarka CAT | RF-API32 |
Heerka Saamiyada | Kaydka dhexdiisa, Qiyaasta Waxsoosaarka Ilaa Tan |
Qaanuunka molecular | C24H29N5O3 |
Miisaanka Molecular | 435.52 |
Meesha dhalaalaysa | 116.0 ~ 117.0 ℃ |
Xasilooni | Hygroscopic |
Summada | Kiimikada Ruifu |
Shayga | Tilmaamaha |
Muuqashada | Budada cad ama ka baxsan;ur aan lahayn, Hygroscopic |
Aqoonsiga | spectrum IR ee muunada waxay la mid tahay heerka tixraaca ee spectrum |
Aqoonsiga | Waqtiga haynta ee ugu sarreysa ee chromatogram-ka diyaarinta tijaabada waxay u dhigantaa tan diyaarinta caadiga ah, sida lagu helay Assay. |
Solubility | Ku milmay Methanol iyo Ethanol, Si aad ah ugu milmay Ethylacetate, Wax yar ku milmay Dichloromethane, Biyo la'aan |
Qoyaanka (KF) | ≤1.00% |
nuugista (420mm) | ≤0.02% (λ=420nm, C=0.05g/ml, L=1cm) |
Hadhaaga dabka | ≤0.10% |
Biraha culus | ≤10pm |
D-Valsartan | ≤1.00% (HPLC) |
Walxaha La Xiriira (HPLC) | |
Butyryl-Valsartan | ≤0.20% |
Benzyl-Valsartan | ≤0.10% |
Xumaanta Keliya Aan La Aqoon | ≤0.10% |
Wadarta wasakhda | ≤0.30% (marka laga reebo D-Valsartan) |
Xalalka Hadhaaga ah (GC) | |
Methanol | ≤3000pm |
Ethyl acetate | ≤5000ppm |
N, N-Dimethylformamide | ≤880pm |
Toluene | ≤890pm |
Daahirnimada / Habka Falanqaynta | > 99.0% (HPLC waxaa lagu xisaabiyaa ku salaysan aan dareeraha lahayn, dareere-free) |
Heerka Imtixaanka | Pharmacopoeia ee Maraykanka (USP) |
Isticmaalka | Walaxda Farmashiyeedka Firfircoon (API) |
Valsartan (CAS: 137862-53-4) Socodka Habka Wax-soo-saarka
Xidhmada: Dhalo, bacda bireed aluminium, 25kg / Durbaan kartoonada, ama sida waafaqsan shuruudaha macmiilka
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka iyo qoyaanka
Shanghai Ruifu Chemical Co., Ltd. waa saaraha iyo soo saaraha ugu horreeya ee Valsartan (CAS: 137862-53-4) oo leh tayo sare leh.Valsartan waa angiotensin II AT1 reseptor antagonist, Antihypertensive, waxay leedahay karti dhiig karka iyo cilmi-baarista wadnaha oo aan shaqeynin.
Saamaynta antihypertensive Valsartan way ka xoog badan tahay kuwa enalapril waxayna ku haboon tahay daawaynta hypertension, dhiig karka dhexdhexaad ilaa dhexdhexaad, iyo gaar ahaan dhiig karka sare ee uu keeno dhaawaca kelyaha.Waxay si aad ah u yareyn kartaa borotiinka bukaanka hypertension ee qaba sonkorowga ama shaqada beerka ee caadiga ah, waxayna kor u qaadi kartaa uric acid iyo sodium kaadi si ay u ilaaliyaan kelyaha.Valsartan waxay sidoo kale ku habboon tahay dhimista dhimashada wadnaha iyo xididdada bukaanka khatarta sare leh (hawl-gabka bidix ama cillad) ka dib marka ay la kulmaan wadna qabad.