Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2 API Tayada Sare
Supply Vonoprazan Fumarate iyo Dhexdhexaadiyaha La Xiriira
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Vonoprazan Fumarate (TAK-438) CAS 1260141-27-2 881681-01-2
| Magaca Kiimikada | Vonoprazan Fumarate |
| La mid ah | TAK-438 |
| Lambarka CAS | 1260141-27-2;881681-01-2 |
| Lambarka CAT | RF-API99 |
| Heerka Saamiyada | Kaydka, Miisaanka Wax-soo-saarka Ilaa boqollaal Kiilogaram |
| Qaanuunka molecular | C21H20FN3O6S |
| Miisaanka Molecular | 461.463 |
| Summada | Kiimikada Ruifu |
| Shayga | Tilmaamaha |
| Muuqashada | Caddaan ama Ku dhawaad-White Crystalline Powder |
| Aqoonsiga 1 H-NMR | Waafaqsan Heerka |
| Aqoonsiga IR | IR nuugista spectrum ee muunada muunada oo leh halbeeg tixraaceed |
| Aqoonsiga HPLC | Wakhtiga haynta ee muunada konkordant oo leh heerka tixraaca |
| Waxyaabaha Biyaha | ≤0.50% |
| Hadhaaga dabka | ≤0.20% |
| Biraha culus (sida Pb) | ≤20pm |
| Walxaha laxidhiidha | |
| Xumaanta A | ≤0.20% |
| Xumaanta B | ≤0.15% |
| Xumaanta C | ≤0.15% |
| Wax kasta oo wasakh kale ah | ≤0.10% |
| Wadarta wasakhda | ≤1.0% |
| Xalalka Haraaga ah | |
| Methanol | ≤0.30% |
| Ethanol | ≤0.50% |
| Ethyl acetate | ≤0.50% |
| Habka Qiimaynta / Falanqaynta | 98.0% ~ 102.0% (Waxaa qoray HPLC) |
| Heerka Imtixaanka | Heerka Ganacsiga |
| Isticmaalka | API |
Xidhmada: Dhalo, boorsada aluminium aluminium, durbaanka kartoonada, 25kg/Drum, ama sida waafaqsan shuruudaha macmiilka.
Xaaladda Kaydinta:Ku kaydi weelasha xiran meel qabow oo qallalan;Ka ilaali iftiinka, qoyaanka.
Vonoprazan Fumurate (TAK-438) (CAS: 1260141-27-2; 881681-01-2), a proton bamka inhibitor (PPI), waa awood iyo af firfircoon oo ah potassium-tartanka acid blocker (P-CAB), oo leh antisecretory. hawlqabad.Vonoprazan Fumarate waxay joojisaa dhaqdhaqaaqa H+,K+-ATPase ee microsomes gastric porcine leh IC50 ee 19 nM ee pH 6.5.Vonoprazan Fumarate (Takecab), oo ay heleen oo ay horumariyeen Takeda iyo Otsuka, waxaa ansixiyay PMDA ee Japan bishii Disembar 2014. boogaha iyo cudurrada kale ee la xiriira gastric acid.Alaabtu waxay leedahay xannibaad xoog leh oo waarta ee dheecaanka acid gastric.Qiyaasta daaweynta, Vonoprazan Fumarate waxay leedahay saameyn yar oo ku saabsan enzymes kale iyo saameyn yar oo ku saabsan hawlaha jir ahaaneed ee jirka.Waa ammaan oo aad loo dulqaadan karo.
