Sodium Valproate (VPA) CAS 1069-66-5 API Factory High Purity
Manufacturer Commercial Supply with High Purity and Stable Quality
Chemical Name: Sodium Valproate (VPA)
CAS: 1069-66-5
Chemical Name | Sodium Valproate |
Synonyms | VPA; Valproic Acid Sodium Salt; Sodium 2-Propylpentanoate |
CAS Number | 1069-66-5 |
CAT Number | RF-API14 |
Stock Status | In Stock, Production Scale Up to Tons |
Molecular Formula | C8H15NaO2 |
Molecular Weight | 166.20 |
Melting Point | 300℃ |
Density | 1.0803 g/cm3 |
Water Solubility | Soluble in Water |
Shipping Condition | Under Ambient Temperature |
Brand | Ruifu Chemical |
Item | Specifications |
Appearance | White or Almost White Crystalline Powder, Hygroscopic |
Identification | Infrared Spectrum By RT comparison Reactions of Sodium Salt |
Solubility | Very Soluble in Water, Freely Soluble in Ethanol |
Acidity or Alkalinity | According to EP Criterions |
Clarity & Color of Solution | According to EP Criterions |
Heavy Metals | ≤20ppm |
Sulfates | ≤200ppm |
Chloride | ≤200ppm |
Loss on Drying | ≤2.0% |
Any Impurity | ≤0.10% (GC) |
Total Impurities | ≤0.30% (GC) |
Assay | 98.5%~101.0% (Titration) |
Test Standard | European Pharmacopeia (EP) |
Usage | Active Pharmaceutical Ingredient (API) |
Package: Bottle, Aluminum foil bag, Cardboard drum, 25kg/Drum, or according to customer's requirement.
Storage Condition: Store in sealed containers at cool and dry place; Protect from light, moisture and pest infestation.
Sodium Valproate (CAS: 1069-66-5) is an anticonvulsant and effective agent for control of both absence and primarily generalized tonic-clonic seizures. Valproic acid sodium salt (Sodium Valproate) is a histone deacetylase (HDAC) inhibitor, with IC50 in the range of 0.5 and 2 mM, also inhibits HDAC1 (IC50, 400 μM), and induces proteasomal degradation of HDAC2. Valproic acid sodium salt activates Notch1 signaling and inhibits proliferation in small cell lung cancer (SCLC) cells. Sodium Valproate (CAS: 1069-66-5) is used in the treatment of epilepsy, bipolar disorder and prevention of migraine headaches.