(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8 ee ≥99.0% Bohloeki ≥99.0% Bortezomib Intermediate High Purity
Fana ka li-Intermediates tse amanang le Bortezomib tse nang le Bohloeki bo Phahameng
(1S,2S,3R,5S)-(+)-2,3-Pinanediol CAS 18680-27-8
(1R,2R,3S,5R)-(-)-2,3-Pinanediol CAS 22422-34-0
Bortezomib CAS 179324-69-7
| Lebitso la Lik'hemik'hale | (1S,2S,3R,5S)-(+)-2,3-Pinanediol |
| Litlhaloso tse tšoanang | (1S,2S,3R,5S) -2,6,6-Trimethylbicyclo[3.1.1]heptane-2,3-diol |
| Nomoro ea CAS | 18680-27-8 |
| Nomoro ea KAtse | RF-CC290 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C10H18O2 |
| Boima ba Molek'hule | 170.25 |
| Solubility | Chloroform, Toluene |
| Boemo ba ho Romela | E Rometsoe ka Tlas'a Mocheso oa Mocheso |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Bosoeu bo Bosoeu ho isa ho Bosoeu ba Crystallized Powder |
| Melting Point | 56.0 ~ 59.0℃ |
| Tahlehelo ka ho Omisa | ≤0.50% |
| Masalla a ho Ignition | ≤0.50% |
| Enantiomeric Feta | ee≥99.0% |
| Mokhoa oa Bohloeki / Analysis | ≥99.0% (GC) |
| Potoloho e Khethehileng [α]20/D | +8.5° ho ea +9.5° (C=6.5, Toluene) |
| Infrared Spectrum | E lumellana |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Metsoako ea Chiral;Li-Intermediates tsa Meriana;Bortezomib Intermediate |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa (1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) e nang le boleng bo phahameng, e sebelisoang haholo ho manyolo. synthesis, motsoako oa li-intermediate tsa meriana le motsoako o motle oa lik'hemik'hale.
Shanghai Ruifu Chemical Co., Ltd. e phetha karolo ea bohlokoa ho k'hemistri ea chiral, k'hamphani e ikemiselitse ho hlahisa metsoako ea chiral.Lihlahisoa tsa rona li rorisoa haholo ke bareki.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8), ke sesebelisoa se sebetsang sa Chiral se sebelisoang ha ho etsoa homochiral α-hydroxyketones le ho rarolla li-ester tsa prolineboronate.Hape ke selelekela sa thuso ho chiral allyl boronate e sebelisoang ho lokisoa ha chiral β-hydroxyallylsilanes.
(1S,2S,3R,5S)-(+)-2,3-Pinanediol (CAS 18680-27-8) ke Bohareng ba Bortezomib (CAS 179324-69-7) ho phekola Multiple Myeloma.Bortezomib, e matla ea ubiquitin proteasome (26S) inhibitor (Ki = 0.6 nM), e ile ea qalisoa US e le phekolo ea myeloma e mengata.Proteasome ena e ea hlokahala bakeng sa ho senyeha ha proteolytic ea boholo ba liprotheine tsa cellular 'me e teng liseleng tsohle.E hlokahala bakeng sa taolo ea lits'ebetso tsa ho ruruha, taolo ea potoloho ea lisele le polelo ea liphatsa tsa lefutso mme ke sepheo sa nalane ea kalafo ea mofets'e.
