2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4 Purity >99.5% (HPLC) Tipiracil Hydrochloride Intermediate Factory
Phepelo ea Moetsi, Boleng bo Phahameng le Theko ea Tlholisano
Tipiracil Hydrochloride (CAS: 183204-72-0) Li-Intermediates tse Amanang
6-(Chloromethyl)uracil CAS: 18592-13-7
6-(Hydroxymethyl)uracil CAS: 22126-44-9
2-Amino-1-Pyrroline Hydrochloride CAS 7544-75-4
Lebitso la Lik'hemik'hale | 2-Amino-1-Pyrroline Hydrochloride |
Litlhaloso tse tšoanang | 3,4-Dihydro-2H-Pyrrol-5-Amine Hydrochloride;2-Aminopyrrolidine HCl |
Nomoro ea CAS | 7544-75-4 |
Nomoro ea KAtse | RF-PI1838 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C4H8N2·HCl |
Boima ba Molek'hule | 120.58 |
Melting Point | 171.0 ho isa ho 175.0 ℃ |
E hloahloa | Hygroscopic |
Brand | Ruifu Chemical |
Ntho | Litlhaloso | Liphetho |
Ponahalo | Phofo e Tshweu | Phofo e Tshweu |
Mokhoa oa Bohloeki / Analysis | >99.5% (HPLC) | 99.8% |
Tšilafalo e Khōlō ka Mong a le Mong | <0.50% | 0.09% |
Litaba tsa Metsi (KF) | <0.50% | 0.45% |
Proton NMR Spectrum | E Ikamahanya le Sebopeho | E lumellana |
Tekanyetso ea Teko | Maemo a Khoebo | |
Tšebeliso | Bohareng ba Tipiracil Hydrochloride (CAS: 183204-72-0) |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
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2-Amino-1-Pyrroline Hydrochloride (CAS: 7544-75-4) ke motsoako oa heterocyclic, o ka sebelisoang e le setsi sa meriana.2-Amino-1-Pyrroline Hydrochloride ke karolo e bohareng ea Tipiracil Hydrochloride (CAS: 183204-72-0) ha ho phekoloa Kankere ea Rectal.Tipiracil Hydrochloride ke inhibitor e matla le ea tlhōlisano ea thymidine phosphorylase (TPase) e nang le boleng ba IC50 ba 35 nM bakeng sa placental TPase ea motho.E khetha TPase ho feta li-enzyme tse ling tsa pyrimidine-metabolizing (IC50s => 1 mM bakeng sa UPase, OPRTase, TK, le DPDase).TPI e thibela phosphorolysis le ho senyeha ha trifluorothymidine, cytotoxic nucleoside, matsoeleng a motho le lisampole tsa colon carcinoma tumor.Tsamaiso ea molomo ea TPI (12.5-50 mg / kg) e ntlafatsa ts'ebetso ea anti-tumor ea trifluorothymidine ka toeba ea AZ-521 ea mofetše oa mala oa xenograft.Metsoako e nang le TPI e 'nile ea sebelisoa bakeng sa phekolo ea kankere ea metastatic colorectal.