2-Chloro-5-Iodobenzoic Acid CAS 19094-56-5 Empagliflozin Intermediate Assay ≥99.0% (HPLC)
Phepelo ea Moetsi, Bohloeki bo Phahameng, Tlhahiso ea Khoebo
Lebitso la lik'hemik'hale: 2-Chloro-5-Iodobenzoic Acid
CAS: 19094-56-5
Lebitso la Lik'hemik'hale | 2-Chloro-5-Iodobenzoic Acid |
Nomoro ea CAS | 19094-56-5 |
Nomoro ea KAtse | RF-PI438 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C7H4ClIO2 |
Boima ba Molek'hule | 282.46 |
Solubility | E qhibiliha ka Methanol |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Likristale tse Bosoeu kapa tse Bosehla bo Sehla |
Mokhoa oa ho hlahloba / oa ho hlahloba | ≥99.0% (HPLC) |
Melting Point | 161.0~163.0℃ |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.20% |
Litšila ka Kakaretso | ≤1.0% |
Litšepe tse boima | ≤20ppm |
Residual Solvent | Ethanol |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | Bohareng ba Empagliflozin (CAS: 864070-44-0) |
2-Chloro-5-Iodobenzoic Acid (CAS 19094-56-5) Synthetic Route
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.
2-Chloro-5-Iodobenzoic Acid (CAS: 19094-56-5) e ka sebelisoa e le setsi sa meriana ka har'a synthesis ea Empagliflozin (CAS: 864070-44-0).Empagliflozin (lebitso la khoebo Jardiance) ke inhibitor ea sodium glucose co-transporter-2 (SGLT-2), mme e etsa hore tsoekere e maling e ntšoe ke liphio ebe e ntšoa ka moroto.Ka Phato 1, 2014, Tsamaiso ea Lijo le Lithethefatsi (FDA) e amohetse semolao setlhare bakeng sa kalafo ea lefu la tsoekere la mofuta oa 2, ho ntlafatsa le ho laola tsoekere ea mali ho batho ba baholo.Empagliflozin ke lithethefatsi tsa boraro tse thibelang SGLT-2 tse amohetsoeng ke FDA.Lithethefatsi tse ling tse peli tsa SGLT-2 inhibitor, Canagliflozin le Dapagliflozin, tsa Johnson Pharmaceuticals, AstraZeneca le Bristol-Myers Squibb ka ho latellana, li amohetsoe ke FDA ka Pulungoana 2013 le Pherekhong 2014 ka ho latellana.