2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6 Linagliptin Bohloeki bo Hare ≥99.0% (HPLC)

Tlhaloso e Khutšoanyane:

Lebitso la Lik'hemik'hale: 2-(Chloromethyl) -4-Methylquinazoline

CAS: 109113-72-6

Bohloeki: ≥99.0% (HPLC)

Ponahalo: Bosehla bo Bosehla ho ea ho Phofo e Bosootho bo Pale

E mahareng bakeng sa Linagliptin (CAS: 668270-12-0) bakeng sa kalafo ea batho ba baholo ba nang le lefu la tsoekere la mofuta oa 2.

Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Linagliptin le li-Intermediate tse Amanang le Moetsi:
Linagliptin CAS 668270-12-0
Linagliptin Nucleus ea Motsoali ea Mahareng CAS 853029-57-9
8-Bromo-3-Methylxanthine CAS 93703-24-3
8-Bromo-7-(2-butyn-1-yl)-3-methylxanthine CAS 666816-98-4
2-(Chloromethyl)-4-Methylquinazoline CAS 109113-72-6
(R)-3-(Boc-Amino)piperidine CAS 309956-78-3
(R)-(-)-3-Aminopiperidine Dihydrochloride CAS 334618-23-4
1-Bromo-2-Butyne CAS 3355-28-0

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	2-(Chloromethyl) -4-Methylquinazoline
Litlhaloso tse tšoanang	Linagliptin ea mahareng A
Nomoro ea CAS	109113-72-6
Nomoro ea KAtse	RF-PI498
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C10H9ClN2
Boima ba Molek'hule	192.64
Botenya	1.251
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Bosehla bo Bosehla ho isa ho Phofo e Bosootho bo Pale
Boitsebiso A	Sample spectrum ea IR e tlameha ho ts'oana le spectrum e tloaelehileng
Boitsebiso B	Nako ea ho boloka tlhōrō ea molao-motheo oa sampuli e tlameha ho lumellana le maemo
Solubility	E qhibiliha ka methylene Chloride;Ha e qhibilihe ka Metsing
Mokhoa oa Bohloeki / Analysis	≥99.0% (HPLC)
Melting Point	60.0 ho isa ho 65.0 ℃
Metsi (KF)	≤0.50%
Masalla a ho Ignition	≤0.50%
Lintho Tse Amanang
Tšilafalo e le Mong	≤0.30%
Litšila ka Kakaretso	≤1.0%
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Hare bakeng sa Linagliptin (CAS: 668270-12-0)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.

Melemo:

LBH:

Kopo:

2-(Chloromethyl) -4-Methylquinazoline (CAS: 109113-72-6) e sebelisoa e le setsi sa ho lokisa Linagliptin (CAS: 668270-12-0), le litšila tsa eona.Linagliptin, e rekisoang tlas'a lebitso la Tradjenta har'a tse ling, ke moriana o sebelisetsoang ho alafa lefu la tsoekere la mofuta oa 2. Hangata ha o ratehe ho feta metformin le sulfonylureas joalo ka kalafo ea pele.E sebelisoa hammoho le boikoetliso le lijo.Ha e khothalletsoe ho lefu la tsoekere la mofuta oa 1.E sebetsa ka ho eketsa tlhahiso ea insulin le ho fokotsa tlhahiso ea glucagon ke manyeme.Linagliptin e amohetsoe bakeng sa tšebeliso ea bongaka United States ka 2011. Linagliptin ke inhibitor e matla haholo, e khethang dipeptidyl peptidase-4 (DPP-4) e nang le IC50 ea 1 nM.