2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5 Remdesivir Hare COVID-19
Remdesivir ea Phepelo ea Khoebo le Litšehare tse Amanang le Boleng bo Phahameng
Remdesivir CAS 1809249-37-3
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2,3,5-Tri-O-benzyl-D-ribonolactone CAS 55094-52-5
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Lebitso la Lik'hemik'hale | 2,3,5-Tri-O-benzyl-D-ribonolactone |
Litlhaloso tse tšoanang | 2,3,5-Tri-O-Benzyl-D-Ribono-1,4-Lactone;Remdesivir ea Mahareng |
Nomoro ea CAS | 55094-52-5 |
Nomoro ea KAtse | RF-PI301 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | C26H26O5 |
Boima ba Molek'hule | 418.49 |
Melting Point | 54.0-55.0℃ |
Boemo ba polokelo | Mocheso oa Kamore |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Se Tiileng se Bosehla kapa Bosweu |
Solubility | E qhibiliha ka CH2Cl2 'me ha e khone ho qhibiliha ho H2O |
NMR le MS | Lokela ho Lumela |
Boitsebiso | IR le TLC |
Mongobo | ≤1.0% |
Masalla a ho Ignition | ≤0.50% |
Tšilafalo efe kapa efe ea Motho ka Mong | ≤0.50% |
Litšepe tse boima | ≤50ppm |
HPLC (210nm) | ≥99.0% |
HPLC (ELSD) | ≥99.0% |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | Bohareng ba Remdesivir (CAS 1809249-37-3) |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
2,3,5-Tri-O-benzyl-D-ribonolactone (CAS 55094-52-5) ke Remdesivir mahareng.Remdesivir (CAS 1809249-37-3) ke sethethefatsi se seng sa antiviral se sehlopheng sa li-nucleotide analogues, se sebelisoang kalafong ea COVID-19.Remdesivir (GS-5734) ke analogue ea antiviral nucleoside e thibelang vaerase ea murine hepatitis (MHV) e nang le EC50 e ts'oanang le SARS-CoV le MERS-CoV.Coronaviruses (CoVs) ke livaerase tsa RNA tse nang le molopo o le mong tse tšoaetsang liphoofolo tse ngata tse ngata.Ho batho, li-CoV li ile tsa amoheloa e le tse atisang ho baka sefuba le pneumonia ho fihlela ho hlaha lefu le matla la ho hema coronavirus (SARS-CoV) ka 2002 le Middle East Respiratory Syndrome coronavirus (MERS-CoV) ka 2012 ho tsoa mehloling ea zoonotic.Remdesivir ke monophosphoramidate prodrug ea C-adenosine nucleoside analogue GS-441524.Liseleng tse liehang tsa boko (DBT) tse tšoaelitsoeng ke MHV, GS-5734 e thibetse MHV ka matla ho feta GS-441524, e nang le GS-5734 EC50 ea 0.03 M. Ho feta moo, litekanyetso tsa EC50 li ile tsa khethoa ka mor'a phekolo ea GS-441524 le GS-5734 le GS-5734 ho SARS-CoV- le MERS-CoV-infected primary human airway epithelial cell (HAE) meetlo.