3-Ethynylaniline CAS 54060-30-9 Bohloeki >99.0% (GC) Erlotinib Hydrochloride Intermediate
Moetsi ea ka sehloohong le mofani oa thepa ea Erlotinib Hydrochloride Intermediates
Erlotinib Hydrochloride CAS 183319-69-9
3-Ethynylaniline CAS 54060-30-9
6,7-Bis(2-Methoxyethoxy)-3H-Quinazolin-4-one CAS 179688-29-0
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Lebitso la Lik'hemik'hale | 3-Ethynylaniline |
Litlhaloso tse tšoanang | 3-Aminophenylacetylene |
Nomoro ea CAS | 54060-30-9 |
Nomoro ea KAtse | RF-PI2241 |
Boemo ba Setoko | Ka Setokong, Matla a Tlhahiso 50MT / Khoeli |
Foromo ea limolek'hule | C8H7N |
Boima ba Molek'hule | 117.15 |
E hloahloa | Ha e Mamele Moeeng, Ha e Mamele Khanya |
Ntlha e belang | 120 ℃/20 mmHg |
Ho qhibiliha ha Metsi | Ha e qhibilihe ka Metsing |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Mokelikeli o Bosehla o Khanyang ho ea ho Brown |
Mokhoa oa Bohloeki / Analysis | >99.0% (GC) |
Metsi ka Karl Fischer | <0.50% |
Masalla a ho Ignition | <0.20% |
Litšila ka Kakaretso | <1.00% |
Matla a Khoheli (20/20℃) | 1.041~1.048 |
Refractive Index n20/D | 1.614~1.6195 |
Infrared Spectrum | E Ikamahanya le Sebopeho |
Proton NMR Spectrum | E Ikamahanya le Sebopeho |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | Pharmaceutical Intermediate;Erlotinib Hydrochloride ea Mahareng |
Sephutheloana: Botlolo ea Fluorinated, 25kg/Drum, kapa ho latela tlhoko ea moreki
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
3-Ethynylaniline, e tsejoang hape e le 3-Aminophenylacetylene (CAS: 54060-30-9) e sebelisoa e le setsi sa meriana.3-Ethynylaniline ke bohareng ba Erlotinib Hydrochloride (CAS: 183319-69-9).Erlotinib Hydrochloride ke molek'hule e nyane ea tyrosine kinase inhibitor e sebetsang ka mokhoa o fetohang ho li-receptor tsa kholo ea epidermal, hydrochloride ea erlotinib, sethethefatsi se lebisitsoeng ho molek'hule.Tsamaiso ea Lijo le Lithethefatsi ea US (FDA) e amohetse erlotinib (Tarceva) e kopantsoeng le gemcitabine e le kalafo ea pele bakeng sa mofetše oa pancreatic o tsoetseng pele le oa metastatic.E sebelisoa haholo-holo e le phekolo ea mohala oa bobeli kapa oa boraro bakeng sa kankere ea matšoafo ea sele e tsoetseng pele kapa ea metstatic non-small cell lung (NSCLC) hape e le phekolo ea kankere ea pancreatic.E sebelisoa e le tyrosine inhibitor bakeng sa phekolo ea NSCLC.Erlotinib Hydrochloride, e leng quinazoline e nkiloeng ka molek'hule e nyenyane ea inhibitor ea epidermal growth receptor (EDGFR) tyrosine kinase, e ile ea amoheloa ka November, 2004, bakeng sa phekolo ea kankere ea matšoafo e tsoetseng pele kapa ea metastatic e seng e nyenyane.