4-[(1-Pyrrolidinylsulfonyl)methyl]aniline CAS 334981-10-1 Purity>99.0% (HPLC) Almotriptan Aniline Precursor Factory

Tlhaloso e Khutšoanyane:

Lebitso: 4 - [(1-Pyrrolidinylsulfonyl)methyl]aniline

CAS: 334981-10-1

Bohloeki: >99.0% (HPLC)

Ponahalo: Bosoeu ho isa ho Bosehla ba Crystalline Powder

Bohareng ba Almotriptan Malate (CAS: 181183-52-8)

Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale 4- [(1-Pyrrolidinylsulfonyl)methyl]aniline
Litlhaloso tse tšoanang 1- [(4-Aminobenzyl)sulfonyl]pyrrolidine;Almotriptan Aniline Precursor
Nomoro ea CAS 334981-10-1
Nomoro ea KAtse RF-PI1948
Boemo ba Setoko Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule Setšoantšo sa C11H16N2O2S
Boima ba Molek'hule 240.32
Melting Point 170.0 ho isa ho 176.0 ℃
Botenya 1.31
Solubility E qhibiliha hanyenyane ka Toluene
Brand Ruifu Chemical

Litlhaloso:

Ntho Litlhaloso
Ponahalo Bosoeu ho isa ho Bosehla ba Crystalline Powder
Mokhoa oa Bohloeki / Analysis >99.0% (HPLC)
Tahlehelo ka ho Omisa <0.50%
Masalla a ho Ignition <0.50%
Ho Se hloeke ho hoholo ho Leng <0.50%
Litšila ka Kakaretso <1.00%
Litšepe tse boima <20ppm
Infrared Spectrum E Ikamahanya le Sebopeho
NMR E Ikamahanya le Sebopeho
Tekanyetso ea Teko Maemo a Khoebo
Tšebeliso Almotriptan Aniline Precursor

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

1

LBH:

Kopo:

4--[(1-Pyrrolidinylsulfonyl) methyl]aniline (CAS: 334981-10-1) ke sebaka se pakeng tsa ho lokisetsa Almotriptan Malate (CAS: 181183-52-8), Almotriptan Aniline Precursor.Almotriptan Malate ke mofuta oa sethethefatsi sa triptan se ka sebelisoang ho phekola hlooho ea migraine.Almotriptan ke karolo ea sehlopha sa lithethefatsi sa li-agonists tse khethang tsa serotonin receptor.Almotriptan e na le kamano e phahameng le e ikhethang bakeng sa li-receptor tsa serotonin 5-HT, e lebisang hape ho vascoconstriction ea methapo ea mali ea boko le ho ama phetiso ea phallo ea mali.Litlamorao tsena li emisa matšoao a bohloko ho romelloa bokong, hape li hatella ho lokolloa ha lintho tse itseng tsa tlhaho tse bakang bohloko, ho nyekeloa ke pelo le matšoao a mang a migraine.Leha ho le joalo, Almotriptan ha e thibele tlhaselo ea migraine.Almotriptan, e rekisitsoeng ka 2000, e na le oralbioavailability e phahameng ka ho fetisisa har'a li-triptan tsohle.Almotriptan e entsoe ka metabolism ke MAO-A le CYP3A4 ka bobeli, ka hona e na le litlamorao tse ntle ha e bapisoa le Sumatriptan.

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