4-(4-Pyridinyl)thiazole-2-thiol CAS 77168-63-9 Bohloeki ≥99.0% Ceftaroline Fosamil Cephalosporin Hare

4-(4-Pyridinyl) thiazole-2-thiol (CAS: 77168-63-9) e sebelisoa e le bohareng ba Ceftaroline Fosamil (TAK-599).Ceftaroline Fosamil ke cephalosporin antibacterial agent e ileng ea amoheloa United States ka Mphalane 2010 bakeng sa kalafo ea IV ea tšoaetso e matla ea baktheria ea letlalo le sebopeho sa letlalo (ABSSSI) le pneumonia ea baktheria e fumanoang ke sechaba (CABP).Ceftaroline Fosamil ke prodrug e qhibilihang ka metsing, N-phosphono ea ceftaroline (T-91825), e pharaletseng, e thibelang likokoana-hloko e nang le ts'ebetso e matla khahlanong le mefuta ea Staphylococcus aureus (MRSA) e hanyetsanang le methicillin, S. pneumonia e hanyetsanang le lithethefatsi, le gram e tloaelehileng - diphoofolo tse mpe.Ceftaroline e tlama ho PBP2a hammoho le tse ling tsa PBP tse nang le kamano e phahameng, ka lebaka leo, e boloka mosebetsi o matla.Ceftaroline e bontša tšebetso e khahlano le likokoana-hloko tse ngata tsa gram-positive, ho kenyeletsoa β-lactam-susceptible and -resistant S. aureus, vancomycin-resistant S. aureus, le mefuta e hanyetsanang le e hlaselehang habonolo ea S. pneumoniae empa e na le tšebetso e fokolang khahlanong le Enterococcus sp.Ts'ebetso ea antibacterial ea gram-negative ea ceftaroline e lekanyelitsoe haholo ho likokoana-hloko tsa phefumoloho tse kang Moraxella catarrhalis le Haemophilus influenzae.