4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9 Purity >98.5% (HPLC) Lenvatinib Mesylate Intermediate Factory

Tlhaloso e Khutšoanyane:

Lebitso: 4-Chloro-7-Methoxyquinoline-6-Carboxamide

CAS: 417721-36-9

Bohloeki: >98.5% (HPLC)

Ponahalo: Bosoeu bo Bosoeu ho ea ho Phofo e Bosehla bo Khanyang

Bohareng ba Lenvatinib Mesylate CAS 857890-39-2

Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Ruifu Chemical Supply Lenvatinib Mesylate Intermediates Ka Bohloeki bo Phahameng
Lenvatinib Mesylate CAS 857890-39-2
4-Chloro-7-Methoxyquinoline-6-Carboxamide CAS 417721-36-9
Desquinolinyl Lenvatinib;1-(2-Chloro-4-Hydroxyphenyl)-3-Cyclopropylurea CAS 796848-79-8
Methyl 7-Methoxy-4-Oxo-1,4-Dihydroquinoline-6-Carboxylate CAS 205448-65-3
Methyl 4-Amino-2-Methoxybenzoate CAS 27492-84-8
5-(Methoxymethylene) -2,2-Dimethyl-1,3-Dioxane-4,6-Dione CAS 15568-85-1
4-Amino-3-Chlorophenol CAS 17609-80-2
4-Amino-3-Chlorophenol Hydrochloride CAS 52671-64-4
Methyl 4-Chloro-7-Methoxyquinoline-6-Carboxylate CAS 205448-66-4

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	4-Chloro-7-Methoxyquinoline-6-Carboxamide
Litlhaloso tse tšoanang	4-Chloro-7-Methoxy-6-Quinolinecarboxamide;Tšilafalo ea Lenvatinib 12;Tšilafalo ea Lenvatinib B;Tšilafalo ea Lenvatinib LFS-B
Nomoro ea CAS	417721-36-9
Nomoro ea KAtse	RF-PI1971
Boemo ba Setoko	Ka Setokong, Matla a Tlhahiso 50MT / Selemo
Foromo ea limolek'hule	C11H9ClN2O2
Boima ba Molek'hule	236.65
Melting Point	>205℃ (Dec.)
Botenya	1.380±0.060 g/cm3
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e Bosoeu ho ea ho Bosehla bo Khanyang
Mokhoa oa Bohloeki / Analysis	>98.5% (HPLC)
Tahlehelo ka ho Omisa	<0.50%
Masalla a ho Ignition	<0.50%
Litšila ka Kakaretso	<1.50%
Proton NMR Spectrum	E Ikamahanya le Sebopeho
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Lenvatinib Mesylate (CAS: 857890-39-2)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

4-Chloro-7-Methoxyquinoline-6-Carboxamide (CAS: 417721-36-9) e sebelisoa haholo-holo e le bohareng ba Lenvatinib Mesylate (CAS: 857890-39-2).E thehiloe ke Eisai Inc., lenvatinib mesylate ke vascular endothelial growth factor receptor (VEGF) inhibitor e nang le ts'ebetso khahlano le VEGF subtypes 1, 2, le 3 mme e amohetsoe ke FDA ka 2015 bakeng sa kalafo ea mofets'e oa qoqotho o fapaneng o teng sebakeng sa heno. khafetsa, metastatic, kapa tsoelo-pele 'me ha ea ka ea arabela kalafo ea radioactive iodine.Ka Mots'eanong 2016, FDA e ile ea amohela sethethefatsi sena e le kalafo e kopaneng le everolimus bakeng sa kalafo ea advanced renal cell carcinoma.Hobane VEGF (le fibroblast growth factor receptors, e tsejoang e le FGFRs) ho nahanoa hore e phetha karolo ea litsela tsa matšoao a pelo, VEGF2R le FGFR inhibition ho nahanoa hore ke mekhoa e ka morao ea phello e ka sehloohong ea lenvatinib mesylate, e leng khatello ea mali.