5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4 Feme e Hare ea Dapagliflozin
Phepelo ea Moetsi, Bohloeki bo Phahameng, Tlhahiso ea Khoebo
Dapagliflozin (CAS: 461432-26-8) Li-Intermediate tse Amanang:
5-Bromo-2-Chlorobenzoic Acid CAS 21739-92-4
5-Bromo-2-Chloro-4'-Ethoxydiphenylmethane CAS 461432-23-5
2,3,4,6-Tetrakis-O-Trimethylsilyl-D-Gluconolactone CAS 32384-65-9
| Lebitso la Lik'hemik'hale | 5-Bromo-2-Chlorobenzoic Acid |
| Litlhaloso tse tšoanang | 2-Chloro-5-Bromobenzoic Acid |
| Nomoro ea CAS | 21739-92-4 |
| Nomoro ea KAtse | RF-PI439 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C7H4BrClO2 |
| Boima ba Molek'hule | 235.46 |
| Melting Point | 154.0 ho isa ho 156.0 ℃ (lit.) |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo e Bosoeu ho ea ho Bosehla bo Khanyang |
| Tlhahlobo | ≥99.0% |
| Metsi (KF) | ≤0.50% |
| Masalla a ho Ignition | ≤0.30% |
| 2-Chlorobenzoic Acid | ≤0.30% |
| 2-Chloro-3-Bromobenzoic Acid | ≤0.30% |
| Litšila ka Kakaretso | ≤1.0% |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Bohareng ba Dapagliflozin (CAS: 461432-26-8), mofuta oa lefu la tsoekere la mofuta oa II |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.
5-Bromo-2-Chlorobenzoic Acid (CAS: 21739-92-4) e sebelisoa e le ntho e qalang ka har'a synthesis ea Dapagliflozin (CAS: 461432-26-8), khetho ea sodium-glucose cotransporter-2 inhibitor e fokotsang renal. glucose reabsorption mme e sebelisoa ho phekola bakuli ba nang le lefu la tsoekere la mofuta oa II.Dapagliflozin ke inhibitor e matla le e khethang ea SGLT-2(SLC5A2 ) e nang le EC50 ea 1.1 nM.E na le ho kenella hantle ho pholletsa le lisele tsa Caco-2 'me ke substrate bakeng sa P-glycoprotein (P-gp).Dapagliflozin e ile ea amoheloa ka 2012 ke FDA.
