5-Methylisoxazole-4-Carboxylic Acid CAS 42831-50-5 Leflunomide Intermediate Purity >99.0% (HPLC)

Tlhaloso e Khutšoanyane:

Lebitso la lik'hemik'hale: 5-Methylisoxazole-4-Carboxylic Acid

Synonyms: 5-Methyl-4-Isoxazolecarboxylic Acid

CAS: 42831-50-5

Bohloeki: >99.0% (HPLC)

Phofo ea Crystalline e Bosoeu ho isa ho Bosehla bo Bosehla, Ha e Monko

Bohareng ba Leflunomide (CAS: 75706-12-6)

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa 5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) e nang le boleng bo phahameng.Ruifu e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, ts'ebeletso e ntle haholo, palo e nyane le e ngata e fumanehang.Reka 5-Methylisoxazole-4-Carboxylic Acid,Please contact: alvin@ruifuchem.com

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	5-Methylisoxazole-4-Carboxylic Acid
Litlhaloso tse tšoanang	5-Methyl-4-Isoxazolecarboxylic Acid
Ho se hloeke	Leflunomide EP Impurity D/ Leflunomide BP Impurity D
Boemo ba Setoko	Ho Stock, Commercial Scale
Nomoro ea CAS	42831-50-5
Foromo ea limolek'hule	C5H5NO3
Boima ba Molek'hule	127.10 g/mol
Melting Point	145.0 ho isa ho 149.0 ℃(lit.)
Botenya	1.348±0.06 g/cm3
Mocheso oa polokelo.	Sebaka se pholileng le se omileng (2~8℃)
COA & MSDS	E fumaneha
Brand	Ruifu Chemical

Litlhaloso:

Lintho	Maemo a Tlhahlobo	Liphetho
Ponahalo	Phofo ea Crystalline e Bosoeu ho isa ho Bosehla bo Bosehla, Ha e Monko	E lumellana
Melting Point	145.0 ho isa ho 149.0 ℃	147.8 ~ 148.5 ℃
Tahlehelo ka ho Omisa	≤0.50%	0.13%
Masalla a ho Ignition	≤0.10%	0.04%
Litšepe tse boima (Pb)	≤0.002%	<0.002%
3-Methyl Isomeric Compound	≤0.20%	<0.20%
Mokhoa oa Bohloeki / Analysis	>99.0% (HPLC)	99.74%
Infrared Spectrum	E Ikamahanya le Sebopeho	E lumellana
1 H NMR Spectrum	E Ikamahanya le Sebopeho	E lumellana
Qetello	Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng
Lisebelisoa	Pharmaceutical Intermediate of Leflunomide (CAS: 75706-12-6)

Sephutheloana/Bobolokelo/Ho tsamaisa ka sekepe:

Sephutheloana:Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka setshelo se koetsoeng ka thata.Boloka sebakeng se phodileng, se omeletseng (2~8℃) le se nang le moya o hlwekileng hole le dintho tse sa dumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.

Melemo:

Bokhoni bo lekaneng: Lisebelisoa le litsebi tse lekaneng

Tšebeletso ea profeshenale: Tšebeletso e le 'ngoe ea ho reka

Sephutheloana sa OEM: Sephutheloana sa tloaelo le leibole lia fumaneha

Tlhahiso e potlakileng: Haeba e le ka har'a setoko, ho netefalitsoe hore ho tsamaisoa matsatsi a mararo

Thepa e tsitsitseng: Boloka thepa e lekaneng

Tšehetso ea Theknoloji: Tharollo ea theknoloji e teng

Tšebeletso e Tloaelehileng ea ho Kopanya: Ho tloha ho ligrama ho isa ho lik'hilograma

Boleng bo Phahameng: Ho thehile tsamaiso e felletseng ea netefatso ea boleng

LBH:

Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.

Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.

Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.

BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.

Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.

Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.

MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.

Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.

Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.

Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.

Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.

Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.

42831-50-5 - Kotsi le Tšireletseho:

Likhoutu tsa Kotsi
R36/37/38 - Ho hlohlona mahlong, tsamaiso ya moya le letlalo.
R37/38 - Ho halefisa tsamaiso ea ho hema le letlalo.
R36 - Ho teneha mahlong
R10 - E ka cha
Tlhaloso ea Tšireletseho
S22 - U se ke ua hema lerole.
S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36/37/39 - Apara liaparo tse loketseng tse sireletsang, liatlana le tšireletso ea mahlo / sefahleho.
S36 - Apara liaparo tse loketseng tsa tšireletso.
S16 - Qoba hole le mehloli ea mollo.
WGK Jeremane 3
HS Code 2917399090
Kotsi Class TSOHLE

Kopo:

5-Methylisoxazole-4-Carboxylic Acid (CAS: 42831-50-5) ke karolo e bohareng ea motsoako oa Leflunomide (CAS: 75706-12-6).Leflunomide ke mofuta oa lithethefatsi tsa isoxazole immunosuppressive tse nang le ts'ebetso e khahlanong le ho ata, pharmacology ea sejoale-joale e beha sehlahisoa sena e le lithethefatsi tsa antipyretic, analgesic le anti-inflammatory.Sehlahisoa sena se ka fetoloa ka potlako ho metabolites e sebetsang 'me ea phetha karolo ea sebete le mala cytoplasm le microsomes, eona;mochine o ka sehloohong ke nakong ea DNA synthesis, e thibelang ts'ebetso ea enzyme ea bohlokoa-DHODH (DHODH), e le hore li-nucleotides ka har'a B lymphocyte li fokotsehe, li felisa biosynthesis ea DNA le RNA, lisele li ke ke tsa kena s phase, 'me qetellong li ke ke tsa khona ho kena. ho ata, ho fella ka liphello tse khahlanong le rheumatic, e loketse bakeng sa phekolo ea batho ba baholo ba nang le ramatiki e sebetsang ea ramatiki, ankylosing spondylitis, e ka liehisa ho timetsoa ha masapo, ho fokotsa matšoao le matšoao.Ho feta moo, leflunomide e ka boela ea thibela mosebetsi oa tyrosine kinase, kahoo e thibela ho ata ha T cell, B cell le lisele tse se nang 'mele, empa hape, ka biosynthesis inhibition ea cyclooxygenase-2 (COX2), e thibela prostaglandin synthesis le ho sebelisa anti- litlamorao tsa ho ruruha le ho thibela lisele tsa mast le ho lokolloa ha histamine ea basophils.Ha sehlahisoa sena se sebelisoa ho bakuli ba ho fetisetsa litho tsa 'mele, phetoho ea lethal dose e thata, e sebelisoa haholo ho phekola ramatiki ea ramatiki le mafu a mang a autoimmune.