6-O-Methylguanine CAS 20535-83-5 Nelzarabine Intermediate Factory
Fana ka Bohloeki bo Phahameng, Tlhahiso ea Khoebo
Lebitso la lik'hemik'hale: 6-O-Methylguanine
CAS: 20535-83-5
| Lebitso la Lik'hemik'hale | 6-O-Methylguanine |
| Litlhaloso tse tšoanang | 2-Amino-6-Methoxypurine |
| Nomoro ea CAS | 20535-83-5 |
| Nomoro ea KAtse | RF-PI509 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C6H7N5O |
| Boima ba Molek'hule | 165.16 |
| Melting Point | >300℃ (hote.) |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo ea Crystalline e Ntle-Bosoeu |
| Mokhoa oa ho hlahloba / oa ho hlahloba | ≥98.5% (HPLC) |
| Tahlehelo ka ho Omisa | ≤0.50% |
| Masalla a ho Ignition | ≤0.50% |
| Litšila ka Kakaretso | ≤1.5% |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Bohareng ba Nelzarabine (CAS: 121032-29-9), T-ALL & T-LBL |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.
6-O-Methylguanine (CAS: 20535-83-5) e ka sebelisoa e le sebaka se ka hare ho motsoako oa Nelzarabine (CAS: 121032-29-9).Nelarabine ke prodrug bakeng sa deoxyguanosine analogue-9-beta-D-arabinofuranosyl guanine (ara-G).Nelarabine demethylates ka karolo ea adenosine deaminase (ADA) mme e fetoha ara-G.Nelarabine e qapiloe ka katleho pele ke GlaxoSmithKline.Ka la 28 October, 2005 tlas'a tumello ea Tsamaiso ea Lijo le Lithethefatsi ea US, e ile ea fetoha moriana o mocha oa ho phekola T-cell acute lymphoblastic leukemia (T-ALL) le T-Cells lymphoblasticlymphoma (T-LBL) e hanyetsanang le bonyane. mefuta e 'meli ea mekhoa ea chemotherapy kapa e khutlela morao ka mor'a phekolo ea pele.Setlhare sena se secha se ngolisitsoe ka molao United States ka 2006.
