S-Adenosyl-L-Methionine (Ademetionine; SAMe) CAS 29908-03-0
Ruifu Chemical ke moetsi ea ka sehloohong oa S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) e nang le boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka S-Adenosyl-L-Methionine,Please contact: alvin@ruifuchem.com
Lebitso la Lik'hemik'hale | S-Adenosyl-L-Methionine |
Litlhaloso tse tšoanang | Ademetionine;S-Adenosylmethionine;SAMe;SAM;AdoMet |
Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
Nomoro ea CAS | 29908-03-0 |
Foromo ea limolek'hule | Setšoantšo sa C15H22N6O5S |
Boima ba Molek'hule | 398.44 g/mol |
Melting Point | 267.0~269.0℃ |
E hloahloa | Hygroscopic haholo |
Ho qhibiliha ha Metsi | E qhibilihang ka Metsing |
Monko & Tatso | Litšobotsi |
COA & MSDS | E fumaneha |
Mohlala | E fumaneha |
Tšimoloho | Shanghai, China |
Brand | Ruifu Chemical |
Lintho | Litlhaloso | Liphetho |
Ponahalo | E batla e le Bosoeu bo Botle ba Powder (Haholo Hygroscopic) | E tiisitsoe |
Solubility | E qhibilihang ka Metsing | |
Boitsebiso | 1. Karabelo ea lik'hemik'hale | Boitšoaro bo botle |
2. IR: E lumellana le mabala a fumanoeng le RS | E tiisitsoe | |
3. Nako ea ho boloka tlhoro e kholo e kopana le likopo | E tiisitsoe | |
Boleng ba Asiti | 1.5~2.5 | 1.9 |
Ho hlaka le Mmala oa Tharollo | Ha e Mebala Haholo ho Feta RS Y1 | E tiisitsoe |
Metsi ka Karl Fischer | ≤3.00% | 2.2% |
Masalla a ho Ignition | ≤0.30% | 0.14% |
Litšepe tse boima (Pb) | ≤10ppm | <10ppm |
Endotoxin | ≤0.3EU/mg | E tiisitsoe |
Microbiological | Lokela ho Kopana le Tlhokahalo | |
Kakaretso ea Plate Count | ≤1000cfu/g | 55cfu/g |
Yeast & Mold | ≤100cfu/g | 12cfu/g |
E. Coli | Ha e eo/10g | E lumellana |
S. Aureus | Ha e eo/10g | E lumellana |
Salmonella | Ha e eo/10g | E lumellana |
S-Adenosyl-L-Homocysteine | ≤0.50% | 0.10% |
Methioadenosine | ≤1.00% | 0.24% |
Adenine | ≤0.50% | 0.09% |
Lintho Tse Amanang | ||
Litšila tse ling tse kholo ka ho fetisisa | ≤0.20% | 0.01% |
Litšila Tse Ling | ≤0.50% | 0.006% |
(S,S) Isomer | >62.0% | 79.4% |
Butanedisulfonate | 46.0 ~ 49.0% (Motheo ho Omisitsoeng) | 47.5% |
Ademetionine | 50.0 ~ 53.0% (Motheo ho Omisitsoeng) | 52.1% |
Kakaretso ea Litaba | >97.5% (Motheo ho Omisitsoeng) | 99.6% |
Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
Shelf Life | Lilemo tse 2 ha li bolokiloe hantle |
Sephutheloana:Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Likhoutu tsa Kotsi R49 - E ka baka mofetše ka ho hema
R23 - Chefo ka ho hema
R34 - E baka ho cha
Tlhaloso ea Tšireletseho S53 - Qoba ho pepeseha - fumana litaelo tse khethehileng pele u li sebelisa.
S23 - Se ke oa hema mouoane.
S36/37/39 - Apara liaparo tse loketseng tse sireletsang, liatlana le tšireletso ea mahlo / sefahleho.
S45 - Ha ho ka etsahala kotsi kapa ha o ikutlwa o sa phele hantle, batla keletso ho ngaka hanghang (bontsha leibole neng kapa neng ha ho kgoneha.)
HS Code 2934999099
S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) ke cosubstrate e tloaelehileng e amehang ho fetisetsoang ha sehlopha sa methyl.SAMe e ile ea sibolloa ka lekhetlo la pele Italy ke GL Cantoni ka 1952, SAMe ke molek'hule e hlahisoang khafetsa ke lisele tsohle tse phelang, e ka thibela mofetše oa sebete, e khothalletsa ho thehoa ha lisele tsa lefufuru le concrescence, e ka thusa ho loantša ho tepella maikutlong, lefu la alzheimer, lefu la sebete le bohloko ba Osteoarthritis, SAMe joale e amoheloa hohle e le meriana ea bohlokoa ea ho phekola mafu a sebete.Kajeno SAMe e sebelisoa hangata ho tsa meriana, indastering ea lijo tsa bophelo bo botle 'marakeng oa lapeng le oa machabeng.SAMe e rekisoa United States e le tlatsetso ea lijo.
1. S-Adenosyl-L-Methionine ke limatlafatsi tse ntle bakeng sa sebete, tse ka thibelang joala, lithethefatsi le tšenyo ea lisele tsa sebete;
2. S-Adenosyl-L-Methionine e na le phello e matla ea ho thibela lefu la sebete le sa foleng le lintho tse ling tse bakang tšenyo ea sebete, lefu la pelo, kankere joalo-joalo.
3. S-Adenosyl-L-Methionine e fumanoe e sebetsa hantle joaloka lithethefatsi bakeng sa ho phekola ramatiki le ho tepella maikutlo ho hoholo.
4. United States, SAM e rekisoa e le tlatsetso ea phepo e nepahetseng tlas'a lebitso la papatso SAM-e (hape e ngotsoe SAME kapa SAMe).Liphuputso tse ling li bontšitse hore ho nka SAM kamehla ho ka thusa ho loantša ho tepella maikutlong, lefu la sebete le bohloko ba osteoarthritis.Liteko tse ngata tsa kliniki li bontšitse hore ho molemo bakeng sa ho tepella maikutlong, maloetse a itseng a sebete le osteoarthritis.Lipontšo tse ling kaofela ha lia tiisoa.
5. Clinically sebelisoa ho ntlafatsa mosebetsi oa sebete.Ho kopanngoa le L-DOPA bakeng sa phekolo ea lefu la Parkinson ho ka ntlafatsa katleho ea L-dopa le ho fokotsa litla-morao.Bohloko ba lehae, matšoenyeho a nakoana le ho hlobaela sebakeng sa ente li ka bonoa.
S-Adenosyl-L-Methionine (Ademetionine; SAMe) (CAS: 29908-03-0) e boetse e na le phello e ntle ea phekolo ho ramatiki, mesifa ea fibrous, migraine le mafu a mang, 'me e na le phello e fokolang.Hoo e ka bang lilemong tsa bo-1970, SAMe e ne e sebelisoa e le moriana oa ngaka bakeng sa ramatiki Europe.Ka 1999, US FDA e ile ea amohela SAMe e le sehlahisoa sa bophelo bo botle 'me e fetohile e' ngoe ea lihlahisoa tsa phepo e nepahetseng ka ho fetisisa United States.
S-Adenosyl-L-Methionine e lokiselitsoe haholo-holo ke motsoako oa lik'hemik'hale, ho belisoa le phetoho ea enzymatic.Mokhoa oa ho belisoa ke ho eketsa selelekela sa L-Methionine ho setsi sa motheo se nang le mehloli ea C le N, 'me palo e kholo ea S-Adenosylmethionine e ka fumanoa ka ho hlahisa lisele tsa likokoana-hloko.Hona joale ke eona tsela e ka sehloohong ea tlhahiso ea indasteri ea S-Adenosylmethionine.Har'a tsona, likokoana-hloko tse sebelisetsoang ho belisoa li ka fumanoa ka ho hlahloba kapa ho kopanya mekhoa ea kaho, e ngotsoeng lihloohong tse ngata le litokelo tsa molao lapeng le linaheng tse ling.Liphuputso tse ling li fane ka mokhoa oa ho lokisa S-adenosylmethionine, ho sebelisa li-polyhydroxy organic reaagents ho sireletsa mosebetsi oa enzyme, ho sebelisa adenosine triphosphate precursor, L-Methionine le phosphate ions e le substrates, glucose kapa / le maltose e le bafani ba matla, ho eketsa motsoako. ea li-ion tsa tšepe, le ho sebelisa khatello ea tlhahiso e lumellehang ho etsa tlhahiso ea S-Adenosylmethionine liseleng tsohle.Ho sebelisa sebopeho sa li-ion tsa tšepe ho laola phallo ea metabolic ho ntlafatsa ts'ebetso ea ho ikamahanya le matla, ho eketsa li-reagents tsa organic ho sireletsa ts'ebetso ea libaktheria le li-enzyme, ho sebelisa mofuta o hlakileng oa tlhahiso ho lokisa S-Adenosylmethionine, ho khutsufatsa nako ea ho kopanya, le etsa hore sehlahisoa se bokelle ka ntle ho sele, se ka bolokang litšenyehelo tsa karohano e latelang le ho nolofatsa mehato ea ts'ebetso.
Lintlha tse mabapi le polokeho ea nako e telele ea S-Adenosyl-L-Methionine li na le moeli hobane barupeluoa liphuputsong tse ngata ba e nkile ka nako e khutšoane feela.Leha ho le joalo, thutong e 'ngoe ea lefu la sebete le amanang le joala, barupeluoa ba ile ba nka S-Adenosyl-L-methionine ka lilemo tse 2;thutong eo, ha ho litla-morao tse tebileng tse tlalehiloeng.
Batho ba nang le lefu la ho ferekana kelellong (bokuli bo khetholloang ke ho feto-fetoha ha maikutlo, ho tloha ho tepella maikutlong ho ea ho mania) ha baa lokela ho nka SAMe bakeng sa matšoao a bona a tepeletseng ntle le tlas'a tlhokomelo ea mofani oa tlhokomelo ea bophelo hobane SAMe e ka 'na ea mpefatsa matšoao a mania.
Le hoja S-Adenosyl-L-Methionine e 'nile ea sebelisoa ho phekola cholestasis nakong ea bokhachane, tšireletso ea eona nakong ea bokhachane ha e e-s'o thehoe.
SAMe e ka fokotsa litlamorao tsa levodopa (L-dopa), sethethefatsi se sebelisetsoang ho phekola lefu la Parkinson.Hape ho ka etsahala hore SAMe e ka sebelisana le lithethefatsi le li-supplement tsa lijo tse eketsang maemo a serotonin (k'hemik'hale e hlahisoang ke lisele tsa methapo), tse kang li-antidepressants, L-tryptophan, le St. John's wort.
Ho na le ngongoreho ea khopolo-taba mabapi le tšebeliso ea SAMe ke batho ba nang le immunocompromised (joaloka ba nang le HIV).Batho ba nang le immunocompromised ba kotsing ea tšoaetso ea Pneumocystis carinii, 'me SAMe e matlafatsa kholo ea microorganism ena.
Litla-morao tsa SAMe ha li tloaelehe, 'me ha li etsahala hangata ke mathata a manyane joalo ka ho nyekeloa ke pelo kapa ho hlonama ha tšilo ea lijo.