Afatinib Dimaleate Intermediate CAS 314771-88-5 Purity >99.0% (HPLC) Factory Featured Image

Afatinib Dimaleate Intermediate CAS 314771-88-5 Bohloeki >99.0% (HPLC) Factory

Tlhaloso e Khutšoanyane:

Lebitso la Lik'hemik'hale: (S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine

CAS: 314771-88-5

Bohloeki: >99.0% (HPLC)

Ponahalo: Phofo e Bosehla ho ea ho Bosehla bo Khanyang

Bohareng ba Afatinib Dimaleate (CAS: 850140-73-7)

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Ruifu Chemical Supply Intermediates of Afatinib
Afatinib CAS 439081-18-2
Afatinib Dimaleate CAS 850140-73-7
(S)-(+)-3-Hydroxytetrahydrofuran CAS 86087-23-2
(Dimethylamino)acetaldehyde Diethyl Acetal CAS 3616-56-6
trans-4-Dimethylaminocrotonic Acid Hydrochloride CAS 848133-35-7
Diethylphosphonoacetic Acid CAS 3095-95-2
7-Fluoro-6-Nitroquinazolin-4 (1H)-e le 'ngoe CAS 162012-69-3
7-Chloro-6-Nitro-4-Hydroxyquinazoline CAS 53449-14-2
N-(3-Chloro-4-Fluorophenyl)-7-Fluoro-6-Nitroquinazolin-4-Amine CAS 162012-67-1
(S)-N4-(3-Chloro-4-Fluorophenyl)-7-((Tetrahydrofuran-3-yl)oxy)quinazoline-4,6-DiamineCAS 314771-76-1
(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-AmineCAS 314771-88-5

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine
Litlhaloso tse tšoanang	N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-[(3S)-oxolan-3-yl]oxyquinazolin-4-Amine;7-((S)-Tetrahydrofuran-3-yloxy)-4-(3-Chloro-4-Fluorophenyl)amino-6-Nitroquinazoline;Tšilafalo ea Afatinib
Nomoro ea CAS	314771-88-5
Nomoro ea KAtse	RF-PI2027
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C18H14ClFN4O4
Boima ba Molek'hule	404.78
Botenya	1.534±0.060 g/cm3
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e Sehla ho ea ho e Khanyang
Mokhoa oa Bohloeki / Analysis	>99.0% (HPLC)
Tahlehelo ka ho Omisa	<0.50%
Tšilafalo ea Motho ka Mong	<0.50%
Litšila ka Kakaretso	<1.00%
Litšepe tse boima	≤20ppm
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Afatinib Dimaleate (CAS: 850140-73-7)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

(S)-N-(3-Chloro-4-Fluorophenyl)-6-Nitro-7-((Tetrahydrofuran-3-yl)oxy)quinazolin-4-Amine (CAS: 314771-88-5) e sebelisoa ho ho lokisoa ha Afatinib Dimaleate (CAS: 850140-73-7).Afatinib ke sethethefatsi se hlabollang se khahlano le mofets'e, moloko o mocha oa lithethefatsi tse lebisitsoeng molomong, setlhare sa pele sa lefats'e se khahlano le mofets'e se tlamellang lelapa la ErbB ka mokhoa o ke keng oa khutlisoa, 'me se sebetsa hantle le ho lebisitsoe ho thibela lets'oao le bakang kholo ea lisele tsa mofets'e. , ho fokotsa kapa ho liehisa ho ata ha lisele tsa mofetše.Afatinib ke ea sehlopha sa lithethefatsi tse tsejoang e le tyrosine kinase inhibitors.E sebetsa ka ho thibela mosebetsi oa liprotheine tse peli tse amanang haufi-ufi, epidermal growth factor receptor (EGFR) le human epidermal growth factor receptor 2 (HER2).E sebelisoa bakeng sa kalafo ea pele ea bakuli ba nang le mofetše oa matšoafo oa metastatic o seng o monyane.Afatinib ke sethethefatsi se hlabollang se khahlano le mofets'e, moloko o mocha oa lithethefatsi tse lebisitsoeng molomong, setlhare sa pele sa lefats'e se khahlano le mofets'e se tlamellang lelapa la ErbB ka mokhoa o ke keng oa khutlisoa, 'me se sebetsa hantle le ho lebisitsoe ho thibela lets'oao le bakang kholo ea lisele tsa mofets'e. , ho fokotsa kapa ho liehisa ho ata ha lisele tsa mofetše.