Anastrozole CAS 120511-73-1 API Factory High Quality
Phepelo ea Moetsi e nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Anastrozole
CAS: 120511-73-1
Lebitso | Anastrozole |
Litlhaloso tse tšoanang | Arimidex;α,α,α',α'-Tetramethyl-5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-benzenediacetonitrile |
Nomoro ea CAS | 120511-73-1 |
Nomoro ea KAtse | RF-API74 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | C17H19N5 |
Boima ba Molek'hule | 293.37 |
Solubility | E qhibiliha ka DMSO le Ethanol |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
Boitsebiso A | IR/MS E Ikamahanya le maemo a litšupiso |
Boitsebiso B | HPLC le sebopeho sa tlhoro: E tsamaellana le litšupiso |
Melting Point | 81.0 ~ 84.0℃ |
Litaba tsa Metsi (ka KF) | ≤0.30% |
Masalla a ho Ignition | ≤0.10% |
Tahlehelo ka ho Omisa | ≤0.50% |
Litšepe tse boima | ≤10ppm |
Lintho Tse Amanang | |
Tšilafalo A | ≤0.10% |
Tšilafalo B | ≤0.20% |
Tšilafalo C | ≤0.20% |
Tšilafalo D | ≤0.10% |
Tšilafalo E | ≤0.10% |
Tšilafalo e 'Ngoe | ≤0.10% |
Litšila ka Kakaretso | ≤0.50% |
Metsoako e setseng | |
Cyclohexane | ≤0.30% |
Ethyl Acetate | ≤0.50% |
Tlhahlobo | 98.0% ~ 102.0% (ka motheo o omisitsoeng) |
Shelf Life | Likhoeli tse 24 |
Tekanyetso ea Teko | Maemo a Khoebo;United States Pharmacopoeia (USP) Standard |
Tšebeliso | Kalafo ea Kankere ea Matsoele |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Anastrozole (CAS 120511-73-1), ke motsoako o seng oa steroidal, oa moloko oa boraro oa achiral triazole o rekisoang e le ARIMIDEX® ke AstraZeneca Pharmaceuticals LP1.Ke e 'ngoe ea moloko oa boraro oa aromatase inhibitor e leng inhibitor e nang le tlhōlisano le e khethollang ea aromatase, kahoo e thibela phetoho ea testosterone ho estradiol le androstenedione ho estrone.Thibelo ea enzyme ea aromatase e etsahala haholo-holo ka tlholisano ea tlamahano ea aromatase ho hemegroup ea cytochrome P450, ho fokotsa biosynthesis ea estrogen liseleng tsa peripheral tsa 'mele le letsoeleng.
Anastrozole ke kalafo e mamelloang hantle bakeng sa mofetše oa matsoele o sa tsoa qala.Joalo ka li-inhibitors tse ling tsa aromatase, phello ea eona e mpe ka ho fetisisa e ne e le kotsi e eketsehileng ea ho robeha ha masapo, eo bakeng sa anastrozole e neng e lekanyelitsoe ho nako ea kalafo.E na le chefo e bobebe ha e bapisoa le chemotherapy;leha ho le joalo, ho hlokometsoe hore bakuli ba bangata ba phekoloang ka anastrozole ba 'nile ba tletleba ka matšoao a manonyeletso ho feta kamoo ho neng ho lebeletsoe kateng, haholo-holo ho tiea ha digital ho tšoana le lefu la ramatiki.Liteko tse ling tsa bongaka tsa anastrozole bakeng sa basali ba postmenopausal ba nang le mofetše oa matsoele Europe le United States li tlalehile mafu a mesifa le masapo e le liketsahalo tse mpe.Anastrozole (Arimidex®) ke aromatase inhibitor e amohetsoeng ho EU, US le linaheng tse ling lefatšeng ka bophara bakeng sa ho sebelisoa e le phekolo ea adjuvant ho basali ba postmenopausal ba nang le kankere ea matsoele ea pele, hormone receptor-positive.E boetse e amohetsoe ho EU le linaheng tse ling lefatšeng ka bophara bakeng sa ho tsoela pele kalafo ea adjuvant ho basali ba seng ba ntse ba e-na le lilemo tse 2-3 tsa phekolo ea adjuvant tamoxifen bakeng sa kankere ea matsoele.