Apixaban CAS 503612-47-3 Bohloeki ≥99.5% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa Apixaban (CAS: 503612-47-3) ka boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka Apixaban,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | Apixaban |
| Litlhaloso tse tšoanang | 1-(4-Methoxyphenyl) -7-oxo-6-[4-(2-oxopiperidin-1-yl)phenyl] -4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine -3-carboxamide, 4,5,6,7-Tetrahydro-1- (4-methoxyphenyl) -7-oxo-6-[4-(2-oxo-1-piperidinyl) phenyl] -1H-pyrazolo[3, 4-c]pyridine-3-carboxamide, BMS 562247, BMS-562247 |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 503612-47-3 |
| Foromo ea limolek'hule | C25H25N5O4 |
| Boima ba Molek'hule | 459.51 g/mol |
| Melting Point | 235.0~238.0℃ |
| Botenya | 1.42 |
| COA & MSDS | E fumaneha |
| Tšimoloho | Shanghai, China |
| Sehlopha | API |
| Brand | Ruifu Chemical |
| Lintho | Maemo a Tlhahlobo | Liphetho |
| Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu | E lumellana |
| Tahlehelo ka ho Omisa | ≤0.50% | 0.10% |
| Masalla a ho Ignition | ≤0.10% | 0.08% |
| Heavy Metals (as Pb) | ≤20ppm | E lumellana |
| Lintho Tse Amanang | ||
| Tšilafalo efe kapa efe e le 'Ngoe | ≤0.50% | E lumellana |
| Litšila ka Kakaretso | ≤0.50% | E lumellana |
| Mokhoa oa Bohloeki / Analysis | ≥99.5% (HPLC) | 99.9% |
| Infrared Spectrum | E Ikamahanya le Sebopeho | E lumellana |
| 1 H NMR Spectrum | E Ikamahanya le Sebopeho | E lumellana |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso | |
Sephutheloana:Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka setshelo se kwetswe ka thata mme o se boloke sebakeng se phodileng, se omeletseng (2~8℃) le se nang le moya o hlwekileng hole le dintho tse sa dumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Ha ho sehlahisoa se tla fuoa linaha tseo ho tsona sena se ka bang khahlanong le litokelo tsa molao tse teng.Leha ho le joalo boikarabelo ba ho qetela bo ho moreki.
Bakeng sa lipatlisiso tsa mahlale sebelisa feela, eseng molemong oa khoebo, eseng molemong oa batho kapa oa tlhahlobo ea mafu.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Apixaban (CAS: 503612-47-3) ke mofuta o mocha oa moriana oa anticoagulant oa molomo o entsoeng ke Bristol Myers Squibb le Pfizer.Ke mofuta o mocha oa oral Xa factor inhibitor, mme lebitso la eona la khoebo ke Eliquis.Apixaban e sebelisetsoa ho phekola bakuli ba baholo ba etsoang opereishene e khethehileng ea letheka kapa lengole ho thibela venous thromboembolism (VTE)
Apixaban (CAS: 503612-47-3) ke molomo o khethiloeng oa Xa factor inhibitor mme o ka thibela moloko oa thrombin le thrombosis.
Apixaban (CAS: 503612-47-3) ke anticoagulant ea boraro e ncha ea molomo e tla rekisoa, ho latela dabigatran le rivaroxaban, 'me e se e amohetsoe Europe bakeng sa ho thibela venous thromboembolism ho bakuli ba etsoang opereishene ea hip kapa lengole.Har'a li-anticoagulants tsena tse tharo tse amoheloang Europe, ha li bapisoa le mokhoa oa hona joale oa thibelo ea thibelo khahlanong le venous thromboembolism, enoxaparin, rivaroxaban e ipabola tekong ea rekoto, 'me apixaban e atlehile tekong ea pele.Liphello tsa phekolo ea Rivaroxaban li ne li phahame hanyenyane, empa li ile tsa baka mali a mangata ho feta apixaban.Bafuputsi ba re liphapang tsena li bakoa ke nako ea meriana, kaha rivaroxaban e nkiloe lihora tsa 6-8 ka mor'a ho buuoa tekong ea rekoto, ha apixaban e sebelisoa lihora tsa 18 ka mor'a ho buuoa tekong ea pele.Lithethefatsi tsena li na le phello e ntle ea ho phekola ha li sebelisoa haufi le nako ea ho buuoa, empa hape li na le kotsi e eketsehileng ea mali.Lipatlisiso tsa bongaka li bontšitse hore ha li bapisoa le ente ea letsatsi le letsatsi ea 40mg enoxaparin, litekanyetso tsa 2 tsa molomo tsa 2.5mg tsa apixaban li bile le liphello tse molemo tsa thibelo khahlanong le venous thromboembolism ka mor'a ho buuoa ka letheka kapa lengole 'me ha ea ka ea eketsa kotsi ea ho tsoa mali.
Apixaban (CAS: 503612-47-3) ke mofuta o mocha oa oral Xa factor inhibitor e kopantsoeng ke Bristol-Myers Squibb le Pfizer.Lebitso la khoebo ke eratol, e leng mofuta o mocha oa anticoagulant ea molomo.Ka ho thibela ntho ea bohlokoa ea coagulation Xa, apixaban e ka thibela tlhahiso ea thrombin le thrombosis.Ka April 26, 2007, Bristol-Myers Squibb o ile a ikopanya le Pfizer ho phatlalatsa tšebelisano-'moho ho nts'etsopele ea apixaban e ncha ea molomo e nang le Bristol-Myers Squibb e le mokhoa o ntlafalitsoeng oa warfarin.Ho ea ka tumellano ea tšebelisano, Pfizer e tla lefa tefo ea pele ea US $ 0.25 bilione ho Bristol-Myers Squibb ho jara 60% ea kakaretso ea litšenyehelo tsa nts'etsopele ea anticoagulant apixaban (e tla kengoa tšebetsong ho tloha ka Pherekhong 1, 2007), ha Bristol-Myers. Squibb e tla jara karolo e setseng ea 40%, ka hona e fumana tokelo ea ho theha le ho rekisa lithethefatsi ka kopanelo.Ka May 2011, apixaban e bile eena oa pele oa ho amohela thibelo ea venous thrombosis ho bakuli ba baholo ba etsoang opereishene e khethehileng ea letheka kapa lengole linaheng tsa 27 EU, Iceland le Norway.Ka la 20 November, 2012, Komisi ea Europe e ile ea amohela Ererto (apixaban) bakeng sa thibelo ea lefu la stroke le systemic embolism ho bakuli ba baholo ba nang le non-valvular atrial fibrillation (NVAF) e nang le mabaka a le mong kapa a mangata a kotsi.Kamora moo, Tsamaiso ea Lijo le Lithethefatsi ea Canada, Japane, le US FDA li amohetse Ererto?(apixaban) bakeng sa thibelo ea ho otloa ke lefu le tsamaiso ea tsamaiso ho bakuli ba baholo ba nang le non-valvular atrial fibrillation (NVAF) ba nang le kotsi e le 'ngoe kapa tse ngata.Ka April 12, 2013, lithethefatsi tse ncha tsa anticoagulant Eloto (ELIQUIS) (apixaban) tse kopantsoeng ke Bristol-Myers Squibb le Pfizer li phatlalalitsoe ka molao hore li thathamisitsoe Chaena.Ererto ke novel oral factor Xa inhibitor bakeng sa thibelo ea venous thromboembolism (VTE) ho bakuli ba baholo ba nkeloang sebaka sa letheka kapa lengole.Lethathamo la eona le fana ka khetho e ncha e bolokehileng le e sebetsang bakeng sa anticoagulation ea bongaka kamora ho buuoa ka masapo, mme e tlisa litaba tse monate ho bakuli ba Machaena ba nkeloang sebaka sa khetho ea letheka / lengole.Lithuto tsa bongaka li netefalitse hore ha ho bapisoa le 40mg enoxaparin hang ka letsatsi, makhetlo a 2 ka letsatsi, tsamaiso ea molomo ea eratol?(apixaban) 2.5mg e sebetsa haholo bakeng sa ho thibela venous thromboembolism ka mor'a ho buuoa ka letheka kapa lengole, 'me ha e eketse kotsi ea ho tsoa mali.Setšoantšo sa 1 se bontša matlapa a Elotoapixaban a hlahisoang ke Bristol-Myers Squibb le Pfizer.
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