Argatroban CAS 74863-84-6 API Factory High Purity Anticoagulant
Manufacturer Supply Argatroban Related Intermediates:
Ethyl (2R,4R)-4-Methyl-2-Piperidinecarboxylate CAS 74892-82-3
N-Nitro-1,2,3,4-tetradehydro Argatroban Ethyl Ester CAS 74874-09-2
3-Methyl-8-Quinolinesulphonyl Chloride CAS 74863-82-4
Argatroban Monohydrate CAS 141396-28-3
Argatroban Anhydrous CAS 74863-84-6
Lebitso la Lik'hemik'hale | Argatroban |
Litlhaloso tse tšoanang | Argatroban Anhydrous |
Nomoro ea CAS | 74863-84-6 |
Nomoro ea KAtse | RF-API67 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | Setšoantšo sa C23H36N6O5S |
Boima ba Molek'hule | 508.63 |
Melting Point | 188.0 ~ 189.0 ℃ |
Ntlha e belang | 801.3ºC ho 760 mmHg |
Botenya | 1.47g/cm3 |
Boemo ba ho Romela | E Rometsoe ka Tlas'a Mocheso oa Mocheso |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
Boitsebiso ba HPLC | Nako ea ho boloka tlhoro ea mantlha e fumanoeng ho Tharollo ea Teko e lumellana le e fumanoeng ho tsoa ho Standard solution, joalo ka tlhahlobo ho Assay. |
Boitsebiso ba IR | E lumellana le IR Spectrum ea AG RS |
Boitsebiso ba UV | Sebakeng sa 259nm le 332nm wavelength e lokela ho ba le ho monya ho hoholo. |
Metsi | 2.5-4.5% |
Mmala oa Tharollo & Ho Hlakola | Tharollo e Lokela ho Hlakola Mebala |
Amahanya Lintho | |
Ho se hloeke A + Ho se hloeke H | ≤0.10% |
Tšilafalo B | ≤0.10% |
Ho se hloeke C + Ho se hloeke E | ≤0.10% |
Tšilafalo D | ≤0.10% |
Tšilafalo I | ≤0.10% |
Bach ea Tšilafalo e sa Boleloeng | ≤0.10% |
Litšila ka Kakaretso | ≤0.30% |
Metsoako e setseng | |
Methanol | ≤3000ppm |
Ethanol | ≤5000ppm |
Dichloromethane | ≤600ppm |
Ethyl Acetate | ≤5000ppm |
Enantiomer (HPLC) | ≤0.10% |
Isomer Ratio (HPLC) | 30.0%-40.0% |
Chloride | ≤0.01% |
Masalla a ho Ignition | ≤0.10% |
Litšepe tse boima | ≤10ppm |
Likokoana-hloko tsa Endotoxins | <5EU/mg |
Moeli oa Likokoana-hloko | TAMC ≤1000 cfu/g |
Tlhahlobo | 98.0% -102.0% (motheong oa anhydrous) |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | API, Synthetic Antithrombotic Agent Anticoagulant |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea Argatroban (CAS: 74863-84-6) e nang le boleng bo phahameng, API.
Argatroban (CAS: 74863-84-6) ke ntho e ncha ea maiketsetso ea antithrombotic e thusang ho lokisa anticoagulation bona ischemic stroke le ho hasanya intravascular coagulation.Ke anticoagulant eo e leng molek'hule e nyenyane e tobileng thrombin inhibitor.Ka 2000, argatroban e ile ea fuoa tumello ke Tsamaiso ea Lijo le Lithethefatsi (FDA) bakeng sa prophylaxis kapa phekolo ea thrombosis ho bakuli ba nang le heparin-induced thrombocytopenia (HIT).Ka 2002, e ile ea amoheloa hore e sebelisoe nakong ea ho kenella ha pelo ho bakuli ba nang le HIT kapa ba kotsing ea ho e hlahisa.Ka 2012, e ile ea amoheloa ke MHRA UK bakeng sa anticoagulation ho bakuli ba nang le thrombocytopenia Type II (HIT) e bakoang ke heparin ba hlokang phekolo ea parenteral antithrombotic.