Atazanavir CAS 198904-31-3 Purity ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor
Fana ka Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Atazanavir
CAS: 198904-31-3
HIV-1 Protease Inhibitor
API Boleng bo Phahameng, Tlhahiso ea Khoebo
Lebitso la Lik'hemik'hale | Atazanavir |
Litlhaloso tse tšoanang | BMS-232632 |
Nomoro ea CAS | 198904-31-3 |
Nomoro ea KAtse | RF-API70 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | C38H52N6O7 |
Boima ba Molek'hule | 704.86 |
Melting Point | 207.0~209.0℃ |
Solubility | E qhibilihang ka har'a DMSO;Ha e qhibilihe ka Metsing |
Polokelo ea Nako e telele | Boloka Nako e telele ho -20 ℃ |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo e Tshweu |
Sebopeho | Free Base |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.20% |
Litšepe tse boima | ≤20ppm |
Tšilafalo A | ≤0.10% |
Tšilafalo B | ≤0.10% |
Tšilafalo e le Mong | ≤0.20% |
Litšila ka Kakaretso | ≤1.0% |
Mokhoa oa ho hloeka/tlhahlobo | ≥99.0% (HPLC) |
pH | 5.0~8.0 |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | HIV-1 Protease Inhibitor Anti-HIV |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
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Atazanavir (CAS 198904-31-3) ke sethethefatsi sa antiretroviral, novel le azapeptide e matla ea sehlopha sa protease inhibitor (PI).E rekisoa tlas'a lebitso la khoebo Reyataz.Joalo ka li-antiretrovirals tse ling, e sebelisoa ho phekola tšoaetso ea mofuta oa 1 oa HIV-1 (HIV-1) protease enzyme e nang le inhibition kamehla Ki ea 66 nmol/L hape e thibela ho ikatisa ha kokoana-hloko ea HIV-1 ka 50% e sebetsang hantle ea EC50 ho tloha 2.6 ho isa ho 5.3 nmol/L.Atazanavir e tlama ho HIV-1 protease e thibelang ho petsoha ha gag le gag-pol polyprotein, e leng se fellang ka hore ho thehoe li-virion tse sa pheleng liseleng tse nang le tšoaetso ea HIV-1.Atazanavir e na le sebopeho sa lik'hemik'hale se fapaneng sa C-2 le matla a antiretroviral ka kakaretso mefuta e fapaneng ea HIV ha e bapisoa le li-protease inhibitors tse ling, ho kenyeletsoa Indinavir, Nelfinavir, Ritonavir, Saquinavir le Amprenavir.Atazanavir e khetholloa ho li-PI tse ling ka hore e ka fanoa hang ka letsatsi 'me e na le litlamorao tse nyane ho boemo ba lipid ba mokuli.Joalo ka li-protease inhibitors tse ling, e sebelisoa feela hammoho le meriana e meng ea HIV.Atazanavir ke mofuta o mocha oa azapeptide HIV protease inhibitor.Antiviral.E nkoa ka molomo hang ka letsatsi.
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