Atazanavir Sulfate CAS 229975-97-7 Purity ≥99.0% API Factory Anti-HIV HIV-1 Protease Inhibitor
Fana ka Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso la lik'hemik'hale: Atazanavir Sulfate
CAS: 229975-97-7
HIV-1 Protease Inhibitor
API Boleng bo Phahameng, Tlhahiso ea Khoebo
Lebitso la Lik'hemik'hale | Atazanavir sulfate |
Litlhaloso tse tšoanang | BMS-232632 Sulfate |
Nomoro ea CAS | 229975-97-7 |
Nomoro ea KAtse | RF-API71 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | C38H52N6O7.H2SO4 |
Boima ba Molek'hule | 802.93 |
Melting Point | 195.0 ~ 198.0 ℃ |
Solubility | Ha e qhibilihe ka Metsing, ha e qhibilihe ka har'a DMSO |
Polokelo ea Nako e telele | Boloka Nako e telele ho -20 ℃ |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo e tšoeu kapa e sa bosoeu |
Sulfate | 12.0~12.5% |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.10% |
Litšepe tse boima | ≤20ppm |
Tšilafalo e le Mong | ≤0.30% |
Litšila ka Kakaretso | ≤1.0% |
Mokhoa oa ho hloeka/tlhahlobo | ≥99.0% (HPLC) |
pH | 5.0~8.0 |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | HIV-1 Protease Inhibitor Anti-HIV |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Atazanavir Sulfate (BMS-232632 Sulfate) (CAS: 229975-97-7) ke mofuta oa letsoai oa sulfate oa atazanavir o khethiloeng haholo ke HIV-1 protease inhibitor, ke protease inhibitor ea pele e amohelehang bakeng sa tsamaiso ea hang-hang ka letsatsi.Atazanavir Sulfate ke substrate le inhibitor ea CYP3A4, le inhibitor le inducer ea P-glycoprotein (P-gp).Atazanavir Sulfate hape ke SARS-CoV 3CLpro inhibitor e nang le IC50 ea 3.49 μM.Atazanavir Sulfate ke azapeptide le HIV-protease inhibitor e sebelisoang kalafong ea tšoaetso ea HIV le AIDS hammoho le li-Anti-HIV tse ling, e ntlafalitsoe le ho thakholoa ke Bristol-Myers Squibb (BMS), tlasa laesense ea lefats'e ea Novartis, bakeng sa kalafo ea tšoaetso ea HIV.Atazanavir e thakhotsoe US e le Reyataz™ ka Phupu 2003. Antiviral.Atazanavir e bonts'itse hore ka kakaretso e matla ho feta tse hlano tse amohetsoeng hajoale tsa HIV-1 protease inhibitors.Atazanavir e thibela ka mokhoa o ikhethileng ts'ebetso e ikhethileng ea vaerase ea Gag le Gag-Pol polyprotein liseleng tse tšoaelitsoeng ke HIV-1 ka ho tlama sebakeng se sebetsang sa HIV-1 protease, kahoo e thibela ho thehoa ha li-virion tse holileng.Atazanavir ha e sebetse khahlano le HIV-2.