Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Prostate Cancer
Phepelo ea Moetsi e nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso: Bicalutamide
CAS: 90357-06-5
Bicalutamide kalafong ea Kankere e tsoetseng pele ea tšoelesa ea senya
API Boleng bo Phahameng, Tlhahiso ea Khoebo
Lebitso | Bicalutamide |
Litlhaloso tse tšoanang | N-[4-Cyano-3-(trifluoromethyl)phenyl] -3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide |
Nomoro ea CAS | 90357-06-5 |
Nomoro ea KAtse | RF-API76 |
Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
Foromo ea limolek'hule | Setšoantšo sa C18H14F4N2O4S |
Boima ba Molek'hule | 430.37 |
Mocheso oa polokelo | 2-8℃ |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu ho isa ho e tšoeu |
Boitsebiso A | IR: Spectrum ea sampole e lumellana le ea standard standard |
Boitsebiso B | HPLC: Nako ea ho boloka tlhōrō e kholo ea tharollo ea mohlala e lumellana le ea tharollo e tloaelehileng |
Boitsebiso C | Boitsebiso ba Organic Fluoride |
Solubility | E qhibiliha ka bolokolohi ka har'a Acetone le Tetrahydrofuran, e Hanyenyane Hanyenyane ka Ethyl Acetate |
Melting Point | 191.0 ~ 195.0 ℃ |
Litaba tsa Metsi (ka KF) | ≤0.20% |
Litaba tsa Fluoride | 15.9% ~ 18.5% |
Tahlehelo ka ho Omisa | ≤0.50% |
Masalla a ho Ignition | ≤0.10% |
Litšepe tse boima | ≤10ppm |
Metsoako e setseng | |
Tetrahydrofuran | ≤0.072% |
Toluene | ≤0.089% |
N-Hexane | ≤0.029% |
Acetone | ≤0.50% |
Ethyl Acetate | ≤0.50% |
Lintho Tse Amanang | |
N, N'-Dimethyl Acetamide | ≤0.109% |
Bicalutamide Aminobenzonitrile | ≤0.10% |
Motsoako o Amanang oa Bicalutamide A Isomer A | ≤0.10% |
Motsoako o Amanang oa Bicalutamide A Isomer B | ≤0.10% |
Bicalutamide e hlahisoang ke Desfluoro | ≤0.20% |
2-Fluoro Bicalutamide | ≤0.20% |
Deoxy Bicalutamide | ≤0.20% |
Bicalutamide sulfide | ≤0.10% |
Tšilafalo efe kapa efe e sa Boleloeng | ≤0.10% |
Litšila ka Kakaretso | ≤0.50% |
Boholo ba Karolo | 90% <10um;50% <5um |
Tlhahlobo | 98.0% ~ 102.0% (ka motheo o omisitsoeng) |
Liteko tsa Microbiological | |
Kakaretso ea Aerobic Count | ≤500CFU/g |
Litomoso le hlobo | ≤50CFU/g |
Shelf Life | Likhoeli tse 24 |
Tekanyetso ea Teko | Maemo a Khoebo;USP Standard |
Tšebeliso | API, kalafong ea Advanced Prostate Cancer |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Bicalutamide (CAS: 90357-06-5) ke mohanyetsi oa non-steroidal androgen, ea qothisanang lehlokoa le androgen receptor le androgen, e thibela ho kenngoa ha lisele tsa androgen, 'me e thibela ho tlama ha androgens ho setho se lebisitsoeng.E tlama le receptor ea androgen e etsang receptor complex, e kenang khubung 'me e kopantsoe le nucleoprotein, ka lebaka leo e thibela ho hōla ha lisele tsa tumor.E ka ba sethethefatsi sa pele sa kalafo ea pholiso ea mofetše o tsoetseng pele oa tšoelesa ea senya.Bicalutamide e thehiloe United Kingdom, 'maraka oa eona oa pele lefatšeng ka bophara, bakeng sa kalafo ea mofetše o tsoetseng pele oa tšoelesa ea senya hammoho le analoge ea LHRH kapa karohano ea opereishene.Antiandrogen e seng ea steroidal, e khethollang ka mokhoa o ikhethileng, bicalutamide e thibela ketso ea dihydrotestosterone le testosterone libakeng tseo ho shebiloeng ho tsona ka ho tlama ka tlholisano ho cytosolic androgen receptor.Ho tlalehoa hore e mamellehe hantle ntle le litla-morao tsa bohlokoa tsa pelo le methapo ea methapo ka lebaka la molemo oa ho haelloa ke ts'ebetso leha e le efe ea steroid.Ho sebetsa ha bicalutamide joalo ka monotherapy ho bontšitsoe ka bongaka.Litefiso tse ts'episang tsa karabelo li boetse li tlalehiloe ho alafong mofets'e oa colorectal, matsoele, manyeme le mofets'e o seng o monyane oa lisele tsa matšoafo.