Bicalutamide CAS 90357-06-5 API Factory High Quality Advanced Prostate Cancer

Tlhaloso e Khutšoanyane:

Lebitso: Bicalutamide

CAS: 90357-06-5

Ponahalo: Bosoeu ho isa ho Bosoeu ba Crystalline Powder

Tekanyo: 98.0% ~ 102.0%

Bicalutamide kalafong ea Kankere e tsoetseng pele ea tšoelesa ea senya

API Boleng bo Phahameng, Tlhahiso ea Khoebo

Inquiry: alvin@ruifuchem.com


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Lihlahisoa tse Amanang

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Tlhaloso:

Phepelo ea Moetsi e nang le Bohloeki bo Phahameng le Boleng bo tsitsitseng
Lebitso: Bicalutamide
CAS: 90357-06-5
Bicalutamide kalafong ea Kankere e tsoetseng pele ea tšoelesa ea senya
API Boleng bo Phahameng, Tlhahiso ea Khoebo

Lintho tsa Lik'hemik'hale:

Lebitso Bicalutamide
Litlhaloso tse tšoanang N-[4-Cyano-3-(trifluoromethyl)phenyl] -3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropionamide
Nomoro ea CAS 90357-06-5
Nomoro ea KAtse RF-API76
Boemo ba Setoko Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma
Foromo ea limolek'hule Setšoantšo sa C18H14F4N2O4S
Boima ba Molek'hule 430.37
Mocheso oa polokelo 2-8℃
Brand Ruifu Chemical

Litlhaloso:

Ntho Litlhaloso
Ponahalo Phofo ea Crystalline e tšoeu ho isa ho e tšoeu
Boitsebiso A IR: Spectrum ea sampole e lumellana le ea standard standard
Boitsebiso B HPLC: Nako ea ho boloka tlhōrō e kholo ea tharollo ea mohlala e lumellana le ea tharollo e tloaelehileng
Boitsebiso C Boitsebiso ba Organic Fluoride
Solubility E qhibiliha ka bolokolohi ka har'a Acetone le Tetrahydrofuran, e Hanyenyane Hanyenyane ka Ethyl Acetate
Melting Point 191.0 ~ 195.0 ℃
Litaba tsa Metsi (ka KF) ≤0.20%
Litaba tsa Fluoride 15.9% ~ 18.5%
Tahlehelo ka ho Omisa ≤0.50%
Masalla a ho Ignition ≤0.10%
Litšepe tse boima ≤10ppm
Metsoako e setseng
Tetrahydrofuran ≤0.072%
Toluene ≤0.089%
N-Hexane ≤0.029%
Acetone ≤0.50%
Ethyl Acetate ≤0.50%
Lintho Tse Amanang  
N, N'-Dimethyl Acetamide ≤0.109%
Bicalutamide Aminobenzonitrile ≤0.10%
Motsoako o Amanang oa Bicalutamide A Isomer A ≤0.10%
Motsoako o Amanang oa Bicalutamide A Isomer B ≤0.10%
Bicalutamide e hlahisoang ke Desfluoro ≤0.20%
2-Fluoro Bicalutamide ≤0.20%
Deoxy Bicalutamide ≤0.20%
Bicalutamide sulfide ≤0.10%
Tšilafalo efe kapa efe e sa Boleloeng ≤0.10%
Litšila ka Kakaretso ≤0.50%
Boholo ba Karolo 90% <10um;50% <5um
Tlhahlobo 98.0% ~ 102.0% (ka motheo o omisitsoeng)
Liteko tsa Microbiological
Kakaretso ea Aerobic Count ≤500CFU/g
Litomoso le hlobo ≤50CFU/g
Shelf Life Likhoeli tse 24
Tekanyetso ea Teko Maemo a Khoebo;USP Standard
Tšebeliso API, kalafong ea Advanced Prostate Cancer

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.

Melemo:

1

LBH:

Kopo:

Bicalutamide (CAS: 90357-06-5) ke mohanyetsi oa non-steroidal androgen, ea qothisanang lehlokoa le androgen receptor le androgen, e thibela ho kenngoa ha lisele tsa androgen, 'me e thibela ho tlama ha androgens ho setho se lebisitsoeng.E tlama le receptor ea androgen e etsang receptor complex, e kenang khubung 'me e kopantsoe le nucleoprotein, ka lebaka leo e thibela ho hōla ha lisele tsa tumor.E ka ba sethethefatsi sa pele sa kalafo ea pholiso ea mofetše o tsoetseng pele oa tšoelesa ea senya.Bicalutamide e thehiloe United Kingdom, 'maraka oa eona oa pele lefatšeng ka bophara, bakeng sa kalafo ea mofetše o tsoetseng pele oa tšoelesa ea senya hammoho le analoge ea LHRH kapa karohano ea opereishene.Antiandrogen e seng ea steroidal, e khethollang ka mokhoa o ikhethileng, bicalutamide e thibela ketso ea dihydrotestosterone le testosterone libakeng tseo ho shebiloeng ho tsona ka ho tlama ka tlholisano ho cytosolic androgen receptor.Ho tlalehoa hore e mamellehe hantle ntle le litla-morao tsa bohlokoa tsa pelo le methapo ea methapo ka lebaka la molemo oa ho haelloa ke ts'ebetso leha e le efe ea steroid.Ho sebetsa ha bicalutamide joalo ka monotherapy ho bontšitsoe ka bongaka.Litefiso tse ts'episang tsa karabelo li boetse li tlalehiloe ho alafong mofets'e oa colorectal, matsoele, manyeme le mofets'e o seng o monyane oa lisele tsa matšoafo.

Ngola molaetsa wa hao mona mme o re romele wona