Biotin CAS 58-85-5 Assay 97.5 ~ 100.5% Fektheri
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa Biotin (Vitamin H) (CAS: 58-85-5) e nang le boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka Biotin (CAS: 58-85-5),Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | Biotin |
| Litlhaloso tse tšoanang | D-Biotin;D(+)-Biotin;Vithamine H;Bios II;vithamine B7;Coenzyme R;Biotinum |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 58-85-5 |
| Foromo ea limolek'hule | Setšoantšo sa C10H16N2O3S |
| Boima ba Molek'hule | 244.31 g/mol |
| Melting Point | 231.0~233.0℃(lit.) |
| Ho qhibiliha ha Metsi | Hanyane ka Metsing |
| Sollubility ho 0.1mol/L NaOH | Hoo e ka bang Ponaletso |
| Solubility | E Hanyenyane Hantle ka Joala, Chloroform, Ether |
| COA & MSDS | E fumaneha |
| Tšimoloho | Shanghai, China |
| Brand | Ruifu Chemical |
| Lintho | Litlhaloso | Liphetho |
| Ponahalo | Phofo ea Crystalline e tšoeu kapa e batlang e le tšoeu | Phofo e Tšoeu ea Crystalline |
| Boitsebiso | IR e Bapisa le Reference IR Spectrum | E lumellana |
| Nako ea ho Boloka | E lokela ho tšoana le ea RS | E lumellana |
| Phetoho e khethehileng [a]20/D | +89.0° ho ea +93.0° (C=2 ho 0.1 M NaOH) | +90,8° |
| Tlhahlobo | 97.5 ~ 100.5% | 99.8% |
| Tahlehelo ka ho Omisa | <0.50% | 0.05% |
| Lintho Tse Amanang | ||
| Tšilafalo ea Motho ka Mong | <1.00% | E lumellana |
| Litšila ka Kakaretso | <2.00% | E lumellana |
| Metsoako e setseng | ||
| Benzene | <2ppm | <0.2ppm |
| Toluene | <100ppm | <10ppm |
| DMSO | <5000ppm | <500ppm |
| Tlhahlobo ea likokoana-hloko | ||
| Kakaretso ea Aerobic Count | ≤1000cfu/g | E lumellana |
| Kakaretso ea Litomoso le hlobo li baloa | ≤100cfu/g | E lumellana |
| Escherichia Coli | ND/1g | / |
| Staphylococcus Aureus | ND/1g | / |
| Pseudomonas Aeruginosa | ND/1g | / |
| Enterobacteria | ND/1g | / |
| Mefuta ea Salmonella | ND/10g | / |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se kwetswe ka thata mme o se boloke sebakeng se phodileng, se omeletseng (2~8℃) le se nang le moya o hlwekileng hole le dintho tse sa dumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
TLHALOSO Tlhahlobo Biotin e na le NLT 97.5% le NMT 100.5% ea Biotin (C10H16N2O3S).
TS'ELISO TS'OANE
• A. HO AMOHELA INFORARED <197K>
B. E kopana le litlhokahalo ho Liteko tse Khethehileng bakeng sa Potoloho ea Optical, Specific Rotation <781S>.
C. Nako ea ho boloka tlhōrō e kholo ea tharollo ea Sample e lumellana le ea Tharollo e Tloaelehileng, joalokaha e fumanoe ho Assay.
TLHOKOMELO
• TSAMAISO
Tharollo ea buffer: Qhala 1 g ea sodium perchlorate monohydrate ka 500 ml ea metsi, eketsa 1 mL ea phosphoric acid, 'me u hlapolle ka metsi ho 1000 mL.
Mohato oa mobile: Acetonitrile le Buffer solution (8.5: 91.5)
Diluent: Acetonitrile le metsi (1:4)
Tharollo e tloaelehileng: 0.1 mg/mL ea USP Biotin RS ho Diluent.Sonicate haeba ho hlokahala ho qhala
Mohlala oa tharollo: 0.1 mg/mL ea Biotin ka Diluent.Sonicate haeba ho hlokahala ho qhala.
Sistimi ea chromatographic
(Sheba Chromatography <621>, Ho Hlokahala Sistimi.)
Mokhoa: LC
Sesebelisoa: UV 200 nm
Kholomo: 4.6-mm × 15-cm;3-µm e paka L7
Sekhahla sa phallo: 1.2 mL / min
Boholo ba ente: 50 µL
Ho nepahala ha sistimi
Mohlala: Tharollo e tloaelehileng
Litlhoko tsa ho tšoaneleha
Ntlha ea ho qetela: NMT 1.5
Phapang e amanang le maemo: NMT 2.0% bakeng sa liente tse ikatisang
Tlhahlobo
Mehlala: Tharollo e tloaelehileng le Tharollo ea Mohlala
Bala peresente ea Biotin (C10H16N2O3S) karolong ea Biotin e nkiloeng:
Sephetho = (rU/rS) × (CS/CU) × 100
rU = karabelo e phahameng ho tsoa ho Sample solution
rS = karabelo ea tlhōrō ho tsoa ho tharollo e tloaelehileng
CS = mahloriso a USP Biotin RS ka har'a tharollo e tloaelehileng (mg/mL)
CU = mahloriso a Biotin ho Sample solution (mg/mL)
Mekhoa ea ho amohela: 97.5% -100.5%
LITŠILA
• METSOALLE E AMEHANG
Tharollo ea Buffer, Mokhahlelo oa Mohala, Diluent, Tharollo e tloaelehileng, Tharollo ea Mohlala, Sisteme ea Chromatographic le Ho nepahala ha Sisteme: Tsoela pele joalo ka ha ho laetsoe ho Assay.
Tlhahlobo
Mohlala: Tharollo ea mohlala
Lekanya likarabo tse phahameng tsa tharollo ea Mohlala.
Bala peresente ea ho se hloeke ka 'ngoe karolong ea Biotin e nkiloeng:
Sephetho = (rU/rT) × 100
rU = tlhōrō ea karabo ea ho se hloeke ka 'ngoe ho tsoa ho Sample solution
rT = kakaretso ea likarabelo tse phahameng tsa litlhoro tsohle tse tsoang ho Sample solution
Mekhoa ea ho amohela
Ho se hloeke ha motho ka mong: NMT 1.0%
Kakaretso ea litšila: NMT 2.0%
LITEKO TSEKO
• HO PHETOHA HO BONTŠA, HO FETOLA HO TŠOANYEHA <781S>
Tharollo ea mohlala: 20 mg/mL ho 0.1 N sodium hydroxide
Mekhoa ea ho amohela: +89 ° ho ea ho +93 °
KEKELETSO LIHLOKO
• PAKARETSO LE HO BOLOKA: Boloka ka har'a linkho tse thata.
• LITEKELO TSA USP REFERENCE <11>
USP Biotin RS
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Matshwao a Kotsi Xn - A Kotsi
Likhoutu tsa Kotsi R20/21/22 - E kotsi ka ho hema, ka ho kopana le letlalo le haeba e koetsoe.
R36/37/38 - Ho hlohlona mahlong, tsamaiso ya moya le letlalo.
Tlhaloso ea Tšireletseho S24/25 - Qoba ho kopana le letlalo le mahlo.
S36 - Apara liaparo tse loketseng tsa tšireletso.
S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
WGK Jeremane 1
RTECS XJ9088200
LIKHOUTU TSA FLUKA BRAND F 8
TSCA Ho joalo
HS Code 2936290000
Chefo LD50 ka molomo ho Mmutla: > 2000 mg/kg
Biotin (Vitamin H; Vithamine B7) (CAS: 58-85-5)
Biotin ke vithamine e qhibilihang ka metsing ka mefuta e robeli, biotin.Ke coenzyme - kapa enzyme e thusang - e sebelisoang liketsong tse ngata tsa metabolism 'meleng.Dchemicalbook-biotin e ameha ho metabolism ea lipid le protheine, e thusang ho fetola lijo hore e be tsoekere, eo 'mele o ka e sebelisang e le matla.E boetse e bohlokoa bakeng sa ho boloka letlalo, moriri le lera la mucous.
Joaloka motsoako oa lijo, Biotin e sebelisoa haholo bakeng sa likhoho le lijo tsa jala.Hangata karoloana ea boima ba premixed ke 1% -2%.
Biotin ke tlatsetso ea phepo e nepahetseng.Ho latela melaoana ea China GB2760-90, e ka sebelisoa e le indasteri ea lijo e le thuso ea ho lokisa.E na le mesebetsi ea 'mele ho thibela mafu a letlalo le ho khothaletsa metabolism ea lipid joalo-joalo.
Biotin ke carboxylase coenzyme, e kenyang letsoho liketsong tse ngata tsa carboxylation, 'me ke coenzyme ea bohlokoa metabolism ea tsoekere, protheine le mafura.
Biotin e sebelisoa e le se matlafatsang lijo.Biotin e sebelisoa bakeng sa lijo tsa masea ka palo ea 0.1 ~ 0.4mg/kg, mokelikeli o nooang 0.02 ~ 0.08mg/kg.
Biotin e ka sebelisoa bakeng sa ho ngola liprotheine, li-antigen, li-antibodies, nucleic acids (DNA, RNA) joalo-joalo.
Biotin e ka etsa hore moriri o otlolohe, oa thibela ho lahleheloa ke moriri pele ho nako le ho ntlafatsa khanyetso ea tlhaho ea letlalo.E boetse e na le ts'ebetso e itseng ea anti-wrinkle.E ka ntlafatsa sebopeho sa mokhatlo o hlophisitsoeng oa letlalo, ea eketsa ho tenyetseha ha lipekere, ea ntlafatsa sebopeho sa lipekere tse brittle le ho etsa hore lipekere li be ntle le ho boreleli ka ho khothaletsa motsoako oa lipids.
Ho ba sieo ha biotin ho ka baka dermatitis, atrophic glossitis, hyperesthesia, myalgia, malaise, anorexia le phokolo ea mali e bonolo, 'me matšoao a nyamela ka tlatsetso ea biotin.Phello ea eona e tloaelehileng haholo ke ho qhoma ha cystic acne.Empa ho batho ba bangata, esita le tšebeliso e feteletseng ea vithamine ena ha e bake phello e mpe.Leha ho le joalo, bakhachane ha baa lokela ho nka biotin ka lebaka la kotsi ea ho senyeheloa ke mpa.
Chefo ea Biotin e bonahala e le tlase, kalafo ea dermatitis ea seborrheic e nang le litekanyetso tse phahameng tsa Biotin ha ea ka ea senola metabolism e sa tloaelehang ea protheine kapa liphoso tsa lefutso le lintho tse ling tse sa tloaelehang.Liteko tsa liphoofolo li boetse li bonts'a chefo e nyane ea Biotin.
