Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8 Purity ≥99.5% (HPLC) Sitagliptin Phosphate Monohydrate Intermediate

Tlhaloso e Khutšoanyane:

Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid

CAS: 486460-00-8

Bohloeki: ≥99.5% (HPLC)

Ponahalo: Phofo e tšoeu ho isa ho e tšoeu

Bohareng ba Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9) bakeng sa kalafo ea mofuta oa II lefu la tsoekere mellitus

Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Fana ka Sitagliptin Phosphate Monohydrate tse Amanang le Mekhatlo:
Sitagliptin API CAS 486460-32-6
Sitagliptin Phosphate Monohydrate API CAS 654671-77-9
2,4,5-Trifluorophenylacetic Acid CAS 209995-38-0
Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid CAS 486460-00-8
Sitagliptin Triazole Hydrochloride CAS 762240-92-6
Sitagliptin Phosphate Monohydrate Ea Hare CAS 486460-21-3

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid
Litlhaloso tse tšoanang	(R) -Sitagliptin N-Boc-Acid Ho se hloeke
Nomoro ea CAS	486460-00-8
Nomoro ea KAtse	RF-PI1192
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	C15H18F3NO4
Boima ba Molek'hule	333.31
Melting Point	136.0 ~ 138.0℃
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e tšoeu ho isa ho e tšoeu
Boitsebiso ka HPLC	Nako ea ho Boloka Mohlala ke Concordant With Reference Standard
Tahlehelo ka ho Omisa	≤0.50%
Molora oa Sulfate	≤0.50%
Litšepe tse boima	<20ppm
Isomer	≤0.50%
Lintho Tse Amanang
Tšilafalo A	≤0.50%
Tšilafalo E 'ngoe E 'Ngoe	≤0.50%
Litšila ka Kakaretso	≤0.50%
Bohloeki	≥99.5% (HPLC)
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Bohareng ba Sitagliptin Phosphate Monohydrate (CAS: 654671-77-9)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.

Melemo:

LBH:

Kopo:

Boc-(R)-3-Amino-4-(2,4,5-Trifluoro-Phenyl)-Butyric Acid (CAS: 486460-00-8) ke karolo ea bohlokoa ea ho lokisoa ha sitagliptin.Sitagliptinphosphate ke inhibitor ea pele ea dipeptidase -IV(DPP-4) e amohetsoeng ke FDA ka 2006. E sebelisoa ho phekola lefu la tsoekere la mofuta oa II.E na le phello e hlakileng ea hypoglycemic ha e sebelisoa e le mong kapa e kopantsoe le metformin le pioglitazone, 'me e bolokehile hore e ka nkuoa, e mamelloa hantle, le karabelo e fokolang e fokolang.Ka Phato 2009, moriana ona o ile oa amoheloa ke European Union e le moriana oa pele oa kalafo ea lefu la tsoekere la mofuta oa 2.Kamora 2011, linaha ka mor'a tse ling li amohetse motsoako oa sitagliptin phosphate le alpha glycosidase inhibitors kapa insulin.Sitagliptin phosphate ke inhibitor ea pele e amohetsoeng ke FDA ea dipeptidyl peptidase-IV e sebelisoang ho phekola lefu la tsoekere la mofuta oa 2 ho fihlela joale, tlasa lebitso la khoebo la Januvia.