Bortezomib CAS 179324-69-7 Purity ≥99.0% (HPLC) API Factory High Purity
Fana ka li-Intermediates tse amanang le Bortezomib tse nang le Bohloeki bo Phahameng
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Bortezomib CAS 179324-69-7
| Lebitso la Lik'hemik'hale | Bortezomib |
| Litlhaloso tse tšoanang | Velcade, MG-341, PS-341 |
| Nomoro ea CAS | 179324-69-7 |
| Nomoro ea KAtse | RF-API65 |
| Boemo ba Setoko | Ka Setokong, Phatlalatso e Eketsehile ho fihla ho Makholo a Lik'hilograma |
| Foromo ea limolek'hule | Setšoantšo sa C19H25BN4O4 |
| Boima ba Molek'hule | 384.24 |
| Melting Point | 122.0~124.0℃ |
| Botenya | 1.214 |
| Refractive Index | 1.564 |
| Solubility | E qhibiliha ka Chloroform, DMSO, Ethanol le Methanol |
| Botsitso | Hygroscopic le Mongobo oa Sensitive |
| Boemo ba ho Romela | E Rometsoe ka Tlas'a Mocheso oa Mocheso |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo e tšoeu kapa e sa bosoeu |
| Mokhoa oa Bohloeki / Analysis | ≥99.0% (HPLC) |
| Tahlehelo ka ho Omisa | ≤0.50% |
| Masalla a ho Ignition | ≤0.20% |
| Ho potoloha ha Optical | -41.0° ~ -46.0° |
| Tšepe e boima | ≤20ppm |
| Asiti | 4.0~7.0 |
| Isomer | ≤0.50% |
| Tšilafalo e le Mong | ≤0.50% |
| Litšila ka Kakaretso | ≤1.0% |
| Metsoako e setseng | |
| Methanol | ≤0.30% |
| Dichloromethane | ≤0.05% |
| Hexane | ≤0.02% |
| Ethyl Acetate | ≤0.50% |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | API |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard Drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong le mofani oa thepa ea Bortezomib (CAS: 179324-69-7) e nang le boleng bo phahameng, API.
Bortezomib, e rekisoang tlas'a lebitso la Velcade har'a ba bang, ke moriana o thibelang mofetše o sebelisetsoang ho phekola myeloma e mengata le mantle cell lymphoma.Bortezomib e ile ea amoheloa bakeng sa tšebeliso ea meriana United States ho 2003 le European Union ho 2004. E Lethathamong la Meriana ea Bohlokoa ea Mokhatlo oa Lefatše oa Bophelo.Bortezomib ke inhibitor ea pele ea proteasome e amohelehang b US FDA bakeng sa myeloma e mengata, kankere ea mali.Reversible inhibitor ea 26S proteasome-e leng karoloana ea multiprotein e bōpehileng joaloka moqomo e fumanoang khubung le cytosol ea lisele tsohle tsa eukaryotic.Bortezomib ke 26S proteasome inhibitor e khethang le e matla, e leng motsoako oa boronic acid dipeptide.Liphuputso tsa lisele tsa kankere ea batho li bontša Bortezomib ho thibela PKR-like endoplasmic reticulum (ER) kinase le ho matlafatsa khatello ea kelello ea ER, e lebisang ho apoptosis.
