Brexpiprazole CAS 913611-97-9 Purity >99.0% (HPLC) API Factory
Ruifu Chemical Supply Brexpiprazole Intermediates
Brexpiprazole CAS 913611-97-9
7-Hydroxyquinolinone CAS 70500-72-0
4-Bromobenzo[b]thiophene CAS 5118-13-8
1-(1-Benzothiophen-4-yl)piperazine Hydrochloride CAS 913614-18-3
7-(4-Chlorobutoxy)quinolin-2(1H)-one CAS 913613-82-8
4-Chlorobenzo[b]thiophene CAS 66490-33-3
Lebitso la Lik'hemik'hale | Brexpiprazole |
Litlhaloso tse tšoanang | OPC-34712;7-(4-(4-(Benzo[b]thiophen-4-yl)piperazin-1-yl)butoxy)quinolin-2(1H)-one |
Nomoro ea CAS | 913611-97-9 |
Nomoro ea KAtse | RF-PI1982 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C25H27N3O2S |
Boima ba Molek'hule | 433.57 |
Botenya | 1.245±0.060 g/cm3 |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo ea Crystalline e tšoeu kapa e sa Tšoeu |
Boitsebiso | Ka IR |
RT | Tlas'a chirality lokela ho lumellana |
Chloride | E fana ka karabelo ea chloride |
Metsi | 3.0%~4.5% |
Melting Point | 198.0 ~ 202.0 ℃ |
Masalla a ho Ignition | <0.20% |
Litšepe tse boima | ≤10ppm |
Lintho Tse Amanang | |
Tšilafalo ea Motho ka Mong | <0.50% |
Litšila ka Kakaretso | <1.00% |
EE | >99.0% |
Mokhoa oa Bohloeki / Analysis | > 99.0% (HPLC, e ommeng) |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | API |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
Brexpiprazole (CAS: 913611-97-9) ke moemeli oa lithethefatsi ea thusang ho phekola le ho thibela mathata a kelello ho kenyeletsa le mathata a CNS.Brexpiprazole ke sethethefatsi se secha sa antipsychotic se sebetsang e le serotonin ® dopamine action modulator mme se bonts'itse katleho e le kalafo e tlatselletsang ho bakuli ba nang le bothata bo boholo ba khatello ea maikutlo (MDD).Brexpiprazole e bonts'a boemo bo ikhethang ba phekolo ea meriana, e sebetsang e le agonist ea karolo ea serotonin 5-HT1A le dopamine D2 receptors le e le mohanyetsi ea feletseng oa 5-HT2A le noradrenaline α1B / 2C li-receptors, tse nang le kamano e tšoanang ea subnanomolar e tlamang.Brexpiprazole e entsoe ke Otsuka le Lundbeck, e ile ea amoheloa ka 2015 ke FDA bakeng sa phekolo ea schizophrenia le e le phekolo ea tlatsetso bakeng sa ho tepella maikutlong.Brexpiprazole e nkoa e le mohlahlami oa Otsuka's antipsychotic drug aripiprazole (lebitso la khoebo Abilify) eo tokelo ea hae ea molao e felileng ka Phato 2014.