Brigatinib CAS 1197953-54-0 Bohloeki >99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa Brigatinib (AP-26113) (CAS: 1197953-54-0) e nang le boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka Brigatinib,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | Brigatinib |
| Litlhaloso tse tšoanang | AP26113;AP-26113;5-Chloro-N4-[2-(Dimethylphosphinyl)phenyl]-N2-[2-Methoxy-4-[4-(4-Methyl-1-Piperazinyl)-1-Piperidinyl]phenyl] -2,4-Pyrimidinediamine |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 1197953-54-0 |
| Foromo ea limolek'hule | Setšoantšo sa C29H39ClN7O2P |
| Boima ba Molek'hule | 584.09 g/mol |
| Melting Point | >203℃(Dec.) |
| Botenya | 1.31±0.10 g/cm3 |
| COA & MSDS | E fumaneha |
| Tšimoloho | Shanghai, China |
| Brand | Ruifu Chemical |
| Lintho | Litlhaloso | Liphetho |
| Ponahalo | Phofo e tšoeu ho isa ho e tšoeu | E lumellana |
| Mokhoa oa Bohloeki / Analysis | >99.0% (HPLC) | 99.26% |
| Max.Tšilafalo e le Mong | <1.00% | 0.25% |
| Tahlehelo ka ho Omisa | <1.00% | 0.27% |
| Infrared Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| 1H NMR Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Brigatinib (AP-26113) (CAS: 1197953-54-0) ke lipatlisiso tse nyenyane tsa molek'hule tse lebisitsoeng kalafo ea kankere e ntseng e etsoa ke ARIAD Pharmaceuticals, Inc. Brigatinib ke moriana o sebelisetsoang ho phekola kankere e hatellang epidermal growth factor receptor (EGFR) le Anaplastic lymphoma kinase (ALK).Brigatinib ke agonist e khethollang khahlanong le mefuta e sa tšoaneng ea EGFR ho fapana le mefuta e sa tšoaneng ea tlhaho.Setlhare sena se boetse se bonts'a khetho khahlano le mofuta oa fusion ea ALK-EML4, e leng karolo ea mantlha ea phetoho ea parenchyma ea matšoafo.Brigatinib e laetsoe bakuli ba nang le liphatsa tsa lefutso tse sa tloaelehang le ha mofets'e o seng o monyane oa lisele tsa matšoafo (NSCLC) o sa arabele taolong ka meriana e meng.Brigatinib e khetholloa e le kinase inhibitor, eo mokhoa oa eona oa ts'ebetso o kenyelletsang ho hatella ketso ea liprotheine tse sa tloaelehang tse ntlafatsang ho ata ha lisele tsa mofetše.
Brigatinib (CAS: 1197953-54-0) e laeloa ho bakuli ba nang le mefuta e itseng ea NSCLC e hasaneng likarolong tse sa tšoaneng tsa 'mele ho batho ba kileng ba phekoloa ka meriana e meng ea kankere e kang Crizotinib,' me boemo ba bona bo mpefetse. kapa li bontša matšoao a fokolang a ntlafatso.Haholo-holo e ntse e le tlas'a lipatlisiso bakeng sa katleho ea eona ea phekolo ho mofetše o seng o monyenyane oa lisele tsa matšoafo (NSCLC) moo ALK e kenngoa teng 'me liphetoho tsa EGFP li etsahala hangata.
Brigatinib (AP-26113) (CAS: 1197953-54-0) ke inhibitor ea moloko o mocha oa tyrosine kinase, e bontšang katleho e kholo ho ALK + metastatic NSCLC.Ka August 30, 2016, United States FDA e fane ka bugtinib e le phekolo ea katleho le lithethefatsi tse sa tloaelehang bakeng sa ALK + NSCLC ho bakuli ba tsoetseng pele kapa ba sitoang ho mamella Crizotinib, phekolo ea ALK + NSCLC ea moloko oa pele.Etelletsa tlhahlobo ea kopo ea lethathamo pele 'me u lumelle data ea kopo hore e romeloe nako le nako.FDA e amohetse Bugtinib ka la 28 Mmesa, 2017, tlasa lebitso la khoebo Alunbrigtm.
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