Capecitabine CAS 154361-50-9 Bohloeki 98.0%~102.0% API Boleng bo Phahameng
Phaello ea Liphatlalatso Tse Amanang le Capecitabine:
5-Fluorocytosine CAS: 2022-85-7
2',3'-Di-O-acetyl-5'-deoxy-5-fluorocytidine CAS: 161599-46-8
1,2,3-Tri-O-acetyl-5-deoxy-β-D-ribofuranose CAS: 62211-93-2
Capecitabine CAS: 154361-50-9
| Lebitso la Lik'hemik'hale | Capecitabine |
| Nomoro ea CAS | 154361-50-9 |
| Nomoro ea KAtse | RF-API08 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C15H22FN3O6 |
| Boima ba Molek'hule | 359.35 |
| Melting Point | 110.0 ~ 121.0℃ |
| Boemo ba ho Romela | Tlas'a Mocheso oa Ambient |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo e Tshweu |
| Boitsebiso | IR Spectrum sampole e lokela ho tsamaellana le spectrum ea litekanyetso tsa litšupiso |
| Boitsebiso | HPLC: Nako ea ho boloka tlhoro e kholo ea tharollo ea sampole e lokela ho lumellana le maemo a referense. |
| Bohloeki | 98.0% ~ 102.0% (motheong oa anhydrous le o se nang solvent) |
| Ho potoloha ha Optical | +96.0°~+100° |
| Mongobo (KF) | ≤0.30% |
| Mesaletsa ha e tuka | ≤0.10% |
| Litšepe tse boima | ≤20ppm |
| Tšilafalo e Amanang le A | ≤0.30% |
| Related Impurity B | ≤0.30% |
| Tšilafalo e Amanang le C | ≤0.10% (2',3'-Di O-Acety-5'-deoxy-5-Fluoroytidine) |
| Tšilafalo e le 'Ngoe e sa Boleloeng | ≤0.10% |
| Kakaretso ea Litšila tse sa Boleloeng | ≤0.50% |
| Litšila ka Kakaretso | ≤1.5% |
| Residual Solvents (GC) | |
| Methanol | ≤3000ppm |
| Ethanol | ≤5000ppm |
| Dichloromethane | ≤600ppm |
| Ethyl Acetate | ≤5000ppm |
| Toluene | ≤800ppm |
| Pyridine | ≤200ppm |
| Hexane | ≤290ppm |
| Kakaretso ea Aerobic Microbial Count | ≤200cfc/g |
| Litomoso le hlobo li baloa | ≤50cfc/g |
| Tekanyetso ea Teko | United States Pharmacopoeia (USP) |
| Tšebeliso | Kankere ea Matsoele ea Metastatic |
Sephutheloana: Botlolo, Aluminium foil bag, Cardboard drum, 25kg/Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa khanya, mongobo le ho hlaseloa ke likokoanyana.
Capecitabine (CAS: 154361-50-9) ke mofuta o mocha oa lithethefatsi tsa molomo oa fluorinated pyrimidine.Capecitabine e entsoe ke Roche Pharmaceuticals, 'me lebitso la eona la khoebo ke Xeloda.Capecitabine e ka fetoha ka vivo ho ba 5- FU, sethethefatsi sa anti-metabolizim fluorine pyrimidine deoxynucleoside carbamate se lebisitseng lisele tsa mofetše ho thibela karohano ea lisele le ho senya RNA le protheine synthesis.Liphello tsa eona li hokahane haholo le boemo ba polelo ea enzyme ea TP ka lisele tsa neoplastic le ho enzyme ea DPD ka polelo ea vivo.E loketse joalo ka kalafo e 'ngoe bakeng sa bakuli ba mofetše oa matsoele oa mantlha kapa oa metastatic ba sa kang ba arabela lithibela-mafu tsa paclitaxel kapa anthracycline.E le sethethefatsi se thibelang mofetše, hangata se sebelisoa ho alafa mofetše oa matsoele o tsoetseng pele kapa oa metastatic, hammoho le kalafo ea mofets'e oa matšoafo oa sele e seng nyane, mofets'e, mofets'e oa senya, mofets'e oa mokokotlo, mofets'e oa colon, mofets'e oa mala le lihlahala tse ling tse tiileng. .
