Daclatasvir Dihydrochloride Intermediate CAS 1007882-23-6 Bohloeki >98.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa Daclatasvir Dihydrochloride Intermediate (CAS: 1007882-23-6) e nang le boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, palo e nyane le e ngata e fumanehang.Reka Daclatasvir Dihydrochloride Intermediates,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) |
| Litlhaloso tse tšoanang | Daclatasvir Mahareng Ⅱ;Dacaltasvir Mahareng 02;Daclatasvir T-Butyl Ester;Bis(2-Methyl-2-Propanyl) (2S,2'S) -2,2'-[4,4'-Biphenyldiylbis(1H-Imidazole-4,2-diyl)]di(1-Pyrrolidinecarboxylate);Di-tert-butyl 2,2′-([1,1′-Biphenyl]-4,4′-diylbis(1H-Imidazole-5,2-diyl))(2S,2'S)-bis(Pyridineidine-1- Carboxylate);(2S,2'S)-2,2'-([1,1'-Biphenyl]-4,4'-diyldi-1H-Imidazole-5,2-diyl) bis-1-Pyrrolidinecarboxylic Acid 1,1'-Bis (1,1-Dimethylethyl) Ester;Tšilafalo ea Daclatasvir 4 |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 1007882-23-6 |
| Foromo ea limolek'hule | C40H51ClN8O6 |
| Boima ba Molek'hule | 775.35 g/mol |
| Ntlha e belang | 890.2±65.0℃ ho 760 mmHg |
| Botenya | 1.220±0.06 g/cm3 |
| COA & MSDS | E fumaneha |
| Tšimoloho | Shanghai, China |
| Sehlopha | Bohareng ba Daclatasvir Dihydrochloride (CAS: 1009119-65-6) |
| Brand | Ruifu Chemical |
| Lintho | Litlhaloso | Liphetho |
| Ponahalo | Bosehla bo Khanyang ho isa ho Phofo e Sehla | Phofo e Sehla e Khanyang |
| Tahlehelo ka ho Omisa | <1.00% | 0.65% |
| Ho se hloeke ho hoholo ho le Mong | <1.00% | 0.45% |
| Litšila ka Kakaretso | <2.00% | 1.24% |
| Mokhoa oa Bohloeki / Analysis | >98.0% (HPLC) | 98.76% |
| Infrared Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| 1H NMR Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
| Kopo | Bohareng ba Daclatasvir Dihydrochloride (CAS: 1009119-65-6) | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se koetsoe ka thata 'me u se boloke sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o motle hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
Di-tert-Butyl (2S,2'S)-2,2'-(4,4'-Biphenyldiylbis(1H-imidazole-5,2-diyl))di(1-Pyrrolidinecarboxylate) (CAS: 1007882-23-6) ke karolo e bohareng ea Daclatasvir Dihydrochloride (CAS: 1009119-65-6).
Daclatasvir (Daklinza) e fumane boemo ba "tlhahlobo ea pele", e kopantsoeng le Sorafenib bakeng sa phekolo ea bakuli ba baholo ba genotype III ba nang le lefu la sebete le sa foleng la C. Daklinza e bile moriana oa pele o bontšitsoeng hore o sebetsa hantle ho phekola kokoana-hloko ea genotype III hepatitis C. tšoaetso ntle le ts'ebeliso e kopanetsoeng le interferon kapa ribavirin.Interferon le Ribavirin ke lithethefatsi tse peli tse amohetsoeng ke FDA bakeng sa kalafo ea tšoaetso ea kokoana-hloko ea hepatitis C.Hepatitis C ke lefu la kokoana-hloko le ka bakang ho ruruha ha sebete, ho fella ka ho fokotseha ha mosebetsi oa sebete kapa ho hlōleha ha sebete.Bakuli ba bangata ba tšoaelitsoeng ke lefu la sebete la mofuta oa C ha ba na matšoao ho fihlela ho bonahala tšenyo ea sebete, e ka ’nang ea nka lilemo tse ’maloa.Lefatšeng ka bophara, lefu la sebete la mofuta oa III la lefu la sebete la mofuta oa C ke mofuta oa bobeli o atileng haholo oa lefu la sebete la C ka mor'a genotype 1 hepatitis C 'me e nkoa e le e 'ngoe ea mafu a tšoaetsanoang ka ho fetisisa.Daklinza ke pan-genotype NS5A replication complex inhibitor, e nang le katleho ea ho thibela ho pheta-pheta ha RNA le kopano ea kokoana-hloko, phello e 'meli ea antiviral.Bakeng sa lithuto tsa in vitro, Daklinza e bontšitsoe hore e na le phello e khahlanong le kokoana-hloko khahlanong le kokoana-hloko ea lefu la sebete la mofuta oa 1 ~ 6.Daklinza e tsamaisana le temoso ea hore motsoako oa amiodarone, Daklinza le Sofosbuvir o ka baka ho otla ha pelo haholo.Daklinza ke letlapa la molomo le nang le tekanyo e khothalletsoang ea 60 mg bakeng sa 1 linako / d, hammoho le Sofosbuvir bakeng sa libeke tse 12 kaofela.
Khamphani ea lipatlisiso le nts'etsopele: Bristol-Myers Squibb.
Lingoliloeng tsa Patent: WO 2008021927A2 (August 9, 2007).
Nako ea ho bapatsa: Phupu 24, 2015 e thathamisitsoeng United States, lebitso la khoebo Daklinza.
Lipontšo: E sebelisoa hammoho le Sofosbuvir bakeng sa ho phekola genotype 3 a sa foleng lefu la sebete C (HCV) tshwaetso.
Mokhoa oa ts'ebetso: HCV nonstructural protein 5A (NS5A) inhibitors.Liphetoho tse mpe: hlooho le mokhathala.
Sebopeho le litlhaloso: Matlapa, 30 le 60mg.
