2-Cyanophenylboronic Acid 1,3-Propanediol Ester CAS 172732-52-4 Perampanel Bohloeki bo Hare > 99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa 2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) e nang le boleng bo phahameng, bohareng ba Perampanel (CAS: 380917-97-5).Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka li-intermediate tsa Perampanel, Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | 2-Cyanophenylboronic Acid 1,3-Propanediol Ester |
| Litlhaloso tse tšoanang | 2-Cyanobenzeneboronic Acid 1,3-Propanediol Ester;2-(1,3,2-Dioxaborinan-2-yl) benzonitrile |
| Nomoro ea CAS | 172732-52-4 |
| Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
| Foromo ea limolek'hule | C10H10BNO2 |
| Boima ba Molek'hule | 187.01 |
| Melting Point | 46.0~51.0℃ (lit.) |
| Botenya | 1.13±0.10 g/cm3 |
| Solubility | E qhibiliha ka Methanol |
| Botsitso | Hygroscopic |
| Brand | Ruifu Chemical |
| Ntho | Litlhaloso |
| Ponahalo | Phofo e Bosoeu ho isa ho e Khanyang ho ea ho Crystal |
| Mokhoa oa Bohloeki / Analysis | >99.0% (HPLC) |
| Tahlehelo ka ho Omisa | <0.50% |
| Masalla a ho Ignition | <0.20% |
| Tšilafalo e le Mong | <0.50% |
| Litšila ka Kakaretso | <1.00% |
| Heavy Metals (as Pb) | <20ppm |
| Tekanyetso ea Teko | Maemo a Khoebo |
| Tšebeliso | Bohareng ba Perampanel (CAS: 380917-97-5) |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo.
Matshwao a Kotsi Xi - E tenang
Likhoutu tsa Kotsi
R20/21/22 - E kotsi ka ho hema, ho kopana le letlalo le haeba e koetsoe.
R36/37/38 - Ho hlohlona mahlong, tsamaiso ya moya le letlalo.
Tlhaloso ea Tšireletseho
S26 - Ha u kopana le mahlo, hlatsoa hang-hang ka metsi a mangata 'me u batle keletso ea bongaka.
S36/37/39 - Apara liaparo tse loketseng tse sireletsang, liatlana le tšireletso ea mahlo / sefahleho.
Li-ID tsa UN 3439
WGK Jeremane 3
Nomoro ea TSCA
Hazard Note Irritant
2-Cyanophenylboronic Acid 1,3-Propanediol Ester (CAS: 172732-52-4) e sebelisetsoa ho qaptjoa ha Perampanel (CAS: 380917-97-5), mohanyetsi oa AMPA receptor.Perampanel (e fuoe laesense ka 2012) ke AED ea moloko oa boraro e tsejoang ka lebitso la khoebo la Fycompa® (Eisai, Hatfield) UK le Banzel® (Eisai, Hatfield) naheng ea USA.Ka Mphalane 2012, US FDA e ile ea amohela perampanel bakeng sa kalafo ea ho tsietsana ha karolo e itseng ho bakuli ba sethoathoa ba nang le bonyane lilemo tse 12.Perampanel ke mohanyetsi oa pele oa AMPA ho amohela tumello ea FDA joalo ka AED.Li-receptor tsa AMPA glutamate li fumanoa haholo-holo ho li-neuron tsa postsynaptic bokong.Joalo ka mohanyetsi ea khethiloeng, ea se nang tlholisano oa AMPA, parampanel e thibela ho buloa ha mocha oa ion le ho fokotsa ho ata ha bokhoni ba ketso.Perampanel e amohetsoe ke European EMA le US FDA ka Phupu le Mphalane 2012 ka ho latellana, e sebelisoa bakeng sa kalafo ea adjuvant ea bakuli ba nang le ts'arollo e sa fellang ho feta lilemo tse 12 ba nang le kapa ntle le ho ts'oaroa ha tsamaiso ea bobeli.Ka la 22 Phuptjane 2015, Eisai o phatlalalitse hore US FDA e amohetse katoloso ea sesupo sa Pirenparanide hydrate (Fycompa) e le kalafo ea adjuvant bakeng sa ho ts'oaroa ha tonic-clonic ho bakuli ba lefu la sethoathoa ba lilemo tse 12 ho ea holimo.
