CAS 177036-94-1 Purity >99.0% (HPLC) API Factory High Purity

Tlhaloso e Khutšoanyane:

CAS: 177036-94-1

Bohloeki: >99.0% (HPLC)

Ponahalo: Phofo e tšoeu kapa e sa bosoeu

Kalafo ea Pulmonary Arterial Hypertension (PAH)

API Boleng bo Phahameng, Tlhahiso ea Khoebo

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Phepelo ea Khoebo (CAS: 177036-94-1) Basehare ba Amanang:
CAS: 177036-94-1
Methyl 2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoate CAS: 178306-47-3
2-Hydroxy-3-Methoxy-3,3-Diphenylpropanoic Acid CAS: 178306-51-9
(S)-2-Hydroxy-3-Methoxy-3,3-Diphenylpropionic Acid CAS: 178306-52-0
L-Proline Methyl Ester Hydrochlorid CAS: 2133-40-6
4,6-Dimethyl-2-(Methylsulfonyl)pyrimidine CAS: 35144-22-0

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	(S) -2 - [(4,6-Dimethylpyrimidin-2-yl) oxy] -3-Methoxy-3,3-Diphenylpropionic Acid
Litlhaloso tse tšoanang	(+-)-(2S) -2-((4,6-Dimethylpyrimidin-2-yl)oxy)-3-Methoxy-3,3-Diphenylpropanoic Acid
Nomoro ea CAS	177036-94-1
Boemo ba Setoko	Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule	Setšoantšo sa C22H22N2O4
Boima ba Molek'hule	378.43
Phetoho e khethehileng [α]D20	+170.0° ho ea ho +176.0° (C=0.5, MeOH)
Melting Point	172.0~178.0℃(Dec.)
Solubility	Ho qhibiliha haholo ka Methanol;E qhibilihang ka Ethanol, Acetone;Ha e qhibilihe ka Metsing
Brand	Ruifu Chemical

Litlhaloso:

Ntho	Litlhaloso
Ponahalo	Phofo e tšoeu kapa e sa bosoeu
Boitsebiso	HPLC;NMR;LC-MS
Lintho Tse Amanang
Tšilafalo ea Motho ka Mong	≤0.50%
Litšila ka Kakaretso	<1.00%
Tahlehelo ka ho Omisa	≤0.50%
Masalla a ho Ignition	≤0.20%
Litšepe tse boima	≤20ppm
Mokhoa oa Bohloeki / Analysis	>99.0% (HPLC)
Tekanyetso ea Teko	Maemo a Khoebo
Tšebeliso	Mekhatlo ea Meriana

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

LBH:

Kopo:

(CAS: 177036-94-1) APIke mohanyetsi ea khethiloeng oa endothelin-A (ETA) ea hlahisitsoeng bakeng sa phekolo ea molomo ea bakuli ba nang le khatello ea kelello ea methapo ea methapo (PAH), ho ntlafatsa matla a ho ikoetlisa le ho lieha ho mpefala ha kliniki.PAH ke lefu le sa tloaelehang la methapo e nyenyane ea pulmonary e khetholloang ke ho ata ha methapo ea mali le ho tsosolosoa, e leng se etsang hore ho be le keketseho e tsoelang pele ea ho hanyetsa methapo ea mali le khatello ea methapo ea mali, 'me qetellong, ho hlōleha ha ventricular le lefu la pele ho nako.Matšoao a pele a PAH a kenyelletsa ho hema butle-butle, mokhathala, ho otla ha pelo, ho ruruha le ho akheha.Endothelin-1 (ET-1), vasoconstrictor e matla le mitogen ea mesifa e boreleli, ke karolo e ka sehloohong ea ho potlakisa lefu lena, 'me liphello tsa lona li kena lipakeng ka ho kenya tšebetsong li-ETA le li-receptor tsa ETB.Ka Phuptjane 2007, FDA e ile ea fana ka tumello (CAS: 177036-94-1) API bakeng sa kalafo ea hang ka letsatsi ea PAH.