Gefitinib Intermediate CAS 199327-61-2 Bohloeki >99.0% (HPLC)
Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa 7-Methoxy-6- (3-Morpholin-4-ylpropoxy)quinazolin-4 (3H)-One (CAS: 199327-61-2) e nang le boleng bo phahameng, bohareng. ea Gefitinib (CAS: 184475-35-2).Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Reka li-Intermediates tsa Gefitinib,Please contact: alvin@ruifuchem.com
| Lebitso la Lik'hemik'hale | 7-Methoxy-6-(3-Morpholin-4-ylpropoxy)quinazolin-4(3H)-E le 'ngoe |
| Litlhaloso tse tšoanang | 7-Methoxy-6-(3-Morpholinopropoxy)quinazolin-4(3H) -E le 'ngoe;7-Methoxy-6-[3-(4-Morpholinyl) propoxy] -4(3H) -Quinazolinone;7-Methoxy-6-(3-Morpholinopropoxy)quinazolin-4-One |
| litšila | Gefitinib litšila 5;Gefitinib EP Impurity A |
| Boemo ba Setoko | Ka Stock, Tlhahiso ea Khoebo |
| Nomoro ea CAS | 199327-61-2 |
| Foromo ea limolek'hule | C16H21N3O4 |
| Boima ba Molek'hule | 319.36 g/mol |
| Melting Point | 242.0~247.0℃ |
| Botenya | 1.32±0.10 g/cm3 |
| COA & MSDS | E fumaneha |
| Tšimoloho | Shanghai, China |
| Brand | Ruifu Chemical |
| Lintho | Maemo a Tlhahlobo | Liphetho |
| Ponahalo | Phofo e tšoeu ho isa ho e tšoeu | E lumellana |
| Melting Point | 242.0~247.0℃ | 243.6 ~ 244.5 ℃ |
| Tahlehelo ka ho Omisa | <0.50% | 0.15% |
| Masalla a ho Ignition | <0.20% | 0.11% |
| Tšilafalo e le Mong | <0.50% | <0.30% |
| Litšila ka Kakaretso | <1.00% | 0.30% |
| Mokhoa oa Bohloeki / Analysis | >99.0% (HPLC) | 99.7% |
| 1H NMR Spectrum | E tsamaellanang le Sebopeho | E lumellana |
| Qetello | Sehlahisoa se lekoa 'me se lumellana le litlhaloso tse fanoeng | |
| Kopo | Bohareng ba Gefitinib (CAS: 184475-35-2) | |
Sephutheloana:Botlolo ea Fluorinated, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho latela tlhoko ea moreki.
Boemo ba polokelo:Boloka setshelo se kwetswe ka thata mme o se boloke sebakeng se phodileng, se omeletseng (2~8℃) le se nang le moya o hlwekileng hole le dintho tse sa dumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.
Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com
Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.
Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.
Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.
BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.
Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.
Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.
MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.
Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.
Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.
Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.
Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.
Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.
7-Methoxy-6- (3-Morpholin-4-ylpropoxy)quinazolin-4 (3H)-E 'ngoe (CAS: 199327-61-2) ke bohareng / ho se hloeke ha Gefitinib (CAS: 184475-35-2).Gefitinib ke sethethefatsi se ikhethileng haholo se khahlanong le tumor se etselitsoeng kalafo se entsoeng ke AstraZeneca, UK.Gefitinib ke moriana oa pele o lebisitsoeng ho molek'hule bakeng sa kalafo ea mofets'e o seng o monyane oa sele ea matšoafo.E sebetsa ka ho thibela ka mokhoa o ikhethileng tsela ea phetisetso ea matšoao ea epidermal growth factor receptor tyrosine kinase (EGFR-TK).Ka Phato 2002, Gefitinib e ile ea rekisoa Japane ka lekhetlo la pele e le kalafo ea pele bakeng sa mofetše o seng o monyane oa lisele tsa matšoafo tlas'a lebitso la khoebo Iressa.Ka Mots'eanong 2003, Tsamaiso ea Tsamaiso ea Lijo le Lithethefatsi ea US e ile ea amohela Gefitinib e le mokhoa oa boraro oa kalafo ea monotherapy bakeng sa bakuli ba nang le mofetše oa matšoafo oa sele o seng o monyane ba neng ba sa sebetse ka litlhare tse thibelang mofetše tse thehiloeng ho platinum le chemotherapy ea docetaxel.Hajoale, Gefitinib e amohetsoe ke Australia, Japane, Argentina, Singapore le Korea Boroa bakeng sa kalafo ea mofets'e o tsoetseng pele oa mofets'e o seng o monyane oa sele ea matšoafo.Ka la 28 Hlakola, 2005, Tsamaiso ea Lijo le Lithethefatsi ea Chaena e ile ea amohela Gefitinib bakeng sa kalafo ea mofetše oa sele ea matšoafo o tsoetseng pele kapa oa metastatic o seng o monyane (NSCLC) o neng o kile oa fumana chemotherapy.Ha joale ha e so lumelloe ho sebelisoa e le phekolo ea pele bakeng sa NSCLC e tsoetseng pele.Ka la 1 Phupu 2009, European Medicines Agency e ile ea amohela ka molao Gefitinib bakeng sa kalafo ea mothapo oa pele, oa bobeli le oa boraro bakeng sa mofetše oa sele ea matšoafo o tsoetseng pele kapa oa metastatic o seng o monyane o nang le liphetoho tsa liphatsa tsa lefutso tsa EGFR ho batho ba baholo.
