Lapatinib Intermediate CAS 231278-84-5 Bohloeki >98.0% (HPLC)

Tlhaloso e Khutšoanyane:

5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde

CAS: 231278-84-5

Bohloeki: >98.0% (HPLC)

Ponahalo: Phofo e tiileng e Bosehla ho ea ho Bosehla

Bohareng ba API (CAS 388082-77-7)

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com


Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Lapatinib Intermediates:

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde
Litlhaloso tse tšoanang Lapatinib Mahareng 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl] -2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde
Nomoro ea CAS 231278-84-5
Boemo ba Setoko Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane
Foromo ea limolek'hule C26H17ClFN3O3
Boima ba Molek'hule 473.90
Melting Point 225.0 ho isa ho 235.0 ℃
Botenya 1.407±0.06 g/cm3
Refractive Index 1.694
COA & MSDS E fumaneha
Tšimoloho Shanghai, China
Brand Ruifu Chemical

Litlhaloso:

Ntho Litlhaloso
Ponahalo Phofo e Tiileng e Bosehla ho ea ho Bosehla
Mokhoa oa Bohloeki / Analysis >98.0% (HPLC)
Melting Point 225.0~235.0℃
Tahlehelo ka ho Omisa <1.00%
Masalla a ho Ignition <0.50%
Litšila ka Kakaretso <2.00%
Heavy Metals (as Pb) <20ppm
Tekanyetso ea Teko Maemo a Khoebo
Tšebeliso Bohareng ba API (CAS 388082-77-7)

Sephutheloana le Bobolokelo:

Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.

Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo

Melemo:

1

LBH:

www.ruifuchem.com

231278-84-5 - Kopo:

5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) ke bohareng ba API (CAS 388082-77-7 ).(CAS 388082-77-7) ke lithethefatsi tse lebisang tlhokomelo ea kankere ea matsoele e entsoeng ke British GlaxoSmithKline Co. Ke tyrosine kinase inhibitor e ka thibelang ka katleho mosebetsi oa tyrosine kinase oa batho ba epidermal growth factor receptors 1 le 2 (ErbB1, ErbB2).E ka sebetsa ka mokhoa o ikhethileng ka mekhoa e fapaneng, ho netefatsa hore lisele tsa mofetše oa matsoele ha li khone ho fumana matšoao a kholo.E thibela intracellular EGFR (ErbB-1) le HER2 (ErbB-2) libaka tsa ATP, ho thibela tumor cell phosphorylation le ts'ebetso, ho thibela matšoao a tlaase-taolo ka homogeneity le heterogeneity ea EGFR (ErbB-1) le HER2 (ErbB-1) dimerization.

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