Lapatinib Intermediate CAS 231278-84-5 Bohloeki >98.0% (HPLC)
Lebitso la Lik'hemik'hale | 5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde |
Litlhaloso tse tšoanang | Lapatinib Mahareng 3;5-[4-[[3-Chloro-4-[(3-Fluorophenyl)methoxy]phenyl]amino]-6-Quinazolinyl] -2-Furancarboxaldehyde;5-[4-((3-Chloro-4-((3-Fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl]-2-Furaldehyde |
Nomoro ea CAS | 231278-84-5 |
Boemo ba Setoko | Ka Setokong, Sekhahla sa Tlhahiso Ho fihlela ho Lithane |
Foromo ea limolek'hule | C26H17ClFN3O3 |
Boima ba Molek'hule | 473.90 |
Melting Point | 225.0 ho isa ho 235.0 ℃ |
Botenya | 1.407±0.06 g/cm3 |
Refractive Index | 1.694 |
COA & MSDS | E fumaneha |
Tšimoloho | Shanghai, China |
Brand | Ruifu Chemical |
Ntho | Litlhaloso |
Ponahalo | Phofo e Tiileng e Bosehla ho ea ho Bosehla |
Mokhoa oa Bohloeki / Analysis | >98.0% (HPLC) |
Melting Point | 225.0~235.0℃ |
Tahlehelo ka ho Omisa | <1.00% |
Masalla a ho Ignition | <0.50% |
Litšila ka Kakaretso | <2.00% |
Heavy Metals (as Pb) | <20ppm |
Tekanyetso ea Teko | Maemo a Khoebo |
Tšebeliso | Bohareng ba API (CAS 388082-77-7) |
Sephutheloana: Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka lijaneng tse koetsoeng sebakeng se phodileng le se omileng;Sireletsa leseli le mongobo
5-[4-[3-Chloro-4-(3-Fluorobenzyloxy)anilino]-6-Quinazolinyl]furan-2-Carboxaldehyde (CAS: 231278-84-5) ke bohareng ba API (CAS 388082-77-7 ).(CAS 388082-77-7) ke lithethefatsi tse lebisang tlhokomelo ea kankere ea matsoele e entsoeng ke British GlaxoSmithKline Co. Ke tyrosine kinase inhibitor e ka thibelang ka katleho mosebetsi oa tyrosine kinase oa batho ba epidermal growth factor receptors 1 le 2 (ErbB1, ErbB2).E ka sebetsa ka mokhoa o ikhethileng ka mekhoa e fapaneng, ho netefatsa hore lisele tsa mofetše oa matsoele ha li khone ho fumana matšoao a kholo.E thibela intracellular EGFR (ErbB-1) le HER2 (ErbB-2) libaka tsa ATP, ho thibela tumor cell phosphorylation le ts'ebetso, ho thibela matšoao a tlaase-taolo ka homogeneity le heterogeneity ea EGFR (ErbB-1) le HER2 (ErbB-1) dimerization.