1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one CAS 27387-31-1 Ondansetron HCl Dihydrate Intermediate Purity>99.0% (HPLC)

Tlhaloso e Khutšoanyane:

1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one

CAS: 27387-31-1

Bohloeki: >99.0% (HPLC)

Ponahalo: Phofo ea Crystalline e tšoeu kapa e sa Tšoeu

Likahare tsa Ondansetron Hydrochloride Dihydrate

Ikopanye le: Dr. Alvin Huang

Mobile/Wechat/WhatsApp: +86-15026746401

E-Mail: alvin@ruifuchem.com

Re romelle lengolo-tsoibila

Lintlha tsa Sehlahisoa

Lihlahisoa tse Amanang

Li-tag tsa Sehlahisoa

Tlhaloso:

Shanghai Ruifu Chemical Co., Ltd. ke moetsi ea ka sehloohong oa 1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) e nang le boleng bo phahameng.Ruifu Chemical e ka fana ka lits'ebeletso tsa lefats'e ka bophara, theko ea tlholisano, litšebeletso tse ntle haholo, tse nyane le tse ngata tse fumanehang.Please contact: alvin@ruifuchem.com

Li-Intermediate tse Amanang:

Li-Intermediate tse Amanang tsa Ondansetron Hydrochloride Dihydrate

1,3-Cyclohexanedione	CAS 504-02-9
1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one	CAS 27387-31-1
Ondansetron Hydrochloride Dihydrate	CAS 103639-04-9

Lintho tsa Lik'hemik'hale:

Lebitso la Lik'hemik'hale	1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one
Litlhaloso tse tšoanang	1,2,3,4-Tetrahydro-9-Methylcarbazol-4-one;1,2,3,4-Tetrahydro-9-Methyl-4-Oxocarbazole
Boemo ba Setoko	E teng thepeng e teng ka lebenkeleng
Ho se hloeke	Ondansetron USP Related Compound C;Ondansetron EP Ho se hloeke C;Ondansetron Hydrochloride Dihydrate Tšilafalo C
Nomoro ea CAS	27387-31-1
Foromo ea limolek'hule	C13H13NO
Boima ba Molek'hule	199.25 g/mol
Melting Point	199.0 ho isa ho 203.0 ℃
Botenya	1.21±0.10 g/cm3
COA & MSDS	E fumaneha
Brand	Ruifu Chemical

Litlhaloso:

Lintho	Maemo a Tlhahlobo	Liphetho
Ponahalo	Phofo ea Crystalline e tšoeu ho isa ho e tšoeu	E lumellana
Melting Point	199.0 ho isa ho 203.0 ℃	200.0 ho 202.0 ℃
Tšilafalo e le Mong	<0.50%	E lumellana
Litšila ka Kakaretso	<1.00%	E lumellana
Mokhoa oa Bohloeki / Analysis	>99.0% (HPLC)	99.65%
1 H NMR Spectrum	E Ikamahanya le Sebopeho	E lumellana
Qetello	Sehlahisoa se lekoa 'me se lumellana le litlhaloso

Sephutheloana/Bobolokelo/Ho tsamaisa ka sekepe:

Sephutheloana:Botlolo, Aluminium foil bag, 25kg/Cardboard Drum, kapa ho ea ka tlhokahalo ea moreki.
Boemo ba polokelo:Boloka ka setshelo se koetsoeng ka thata.Boloka sebakeng sa polokelo se pholileng, se omeletseng le se nang le moea o pholileng hole le lintho tse sa lumellaneng.Sireletsa leseli le mongobo.
Ho tsamaisa ka sekepe:Tsamaisa lefatšeng ka bophara ka sefofane, ka FedEx / DHL Express.Fana ka thomello e potlakileng le e tšepahalang.

Melemo:

Bokhoni bo lekaneng: Lisebelisoa le litsebi tse lekaneng

Tšebeletso ea profeshenale: Tšebeletso e le 'ngoe ea ho reka

Sephutheloana sa OEM: Sephutheloana sa tloaelo le leibole lia fumaneha

Tlhahiso e potlakileng: Haeba e le ka har'a setoko, ho netefalitsoe hore ho tsamaisoa matsatsi a mararo

Thepa e tsitsitseng: Boloka thepa e lekaneng

Tšehetso ea Theknoloji: Tharollo ea theknoloji e teng

Tšebeletso e Tloaelehileng ea ho Kopanya: Ho tloha ho ligrama ho isa ho lik'hilograma

Boleng bo Phahameng: Ho thehile tsamaiso e felletseng ea netefatso ea boleng

LBH:

Mokhoa oa ho Reka?Ka kopo ikopanyeDr. Alvin Huang: sales@ruifuchem.com or alvin@ruifuchem.com

Phihlelo ea Lilemo Tse 15?Re na le boiphihlelo ba lilemo tse fetang 15 ho etsa le ho romella kantle ho naha mefuta e mengata e fapaneng ea li-intermediate tsa boleng bo holimo tsa meriana kapa lik'hemik'hale tse ntle.

Limmaraka tse ka Sehloohong?Rekisetsa 'maraka oa lapeng, Amerika Leboea, Europe, India, Korea, Japane, Australia, joalo-joalo.

Melemo?Boleng bo phahameng, theko e theko e tlaase, lits'ebeletso tsa litsebi le ts'ehetso ea tekheniki, phano e potlakileng.

BolengTiisetso?Tsamaiso e thata ea taolo ea boleng.Lisebelisoa tsa profeshenale bakeng sa tlhahlobo li kenyelletsa NMR, LC-MS, GC, HPLC, ICP-MS, UV, IR, OR, KF, ROI, LOD, MP, Clarity, Solubility, Microbial limit test, joalo-joalo.

Mehlala?Lihlahisoa tse ngata li fana ka mehlala ea mahala bakeng sa tlhahlobo ea boleng, litšenyehelo tsa ho tsamaisa thepa li lokela ho lefshoa ke bareki.

Feme Audit?Ho amoheloa ha fektheri.Ke kopa o etse kopano esale pele.

MOQ?Ha ho MOQ.Taelo e nyenyane e amoheleha.

Nako ea thomello? Haeba ka har'a setoko, ho netefalitsoe hore ho tsamaisoa ka matsatsi a mararo.

Lipalangoang?Ka Express (FedEx, DHL), ka Moea, ka Leoatle.

Litokomane?Ka mor'a tšebeletso ea thekiso: COA, MOA, ROS, MSDS, joalo-joalo e ka fanoa.

Custom Synthesis?E ka fana ka lits'ebeletso tsa tloaelo tsa ho kopanya ho lekana hantle litlhoko tsa hau tsa lipatlisiso.

Litefiso Melao?Invoice ea Proforma e tla romelloa pele kamora netefatso ea odara, e kenyellelitseng tlhahisoleseling ea rona ea banka.Tefo ka T/T (Telex Transfer), PayPal, Western Union, joalo-joalo.

27387-31-1 - Kotsi le Tšireletseho:

Likhoutu tsa Kotsi
R36/37/38 - Ho hlohlona mahlong, tsamaiso ya moya le letlalo.
R52/53 - E kotsi ho tse phelang metsing, e ka baka liphello tse mpe tsa nako e telele tikolohong ea metsing.
R25 - E chefo ha e koetsoe
Tlhaloso ea Tšireletseho
S22 - U se ke ua hema lerole.
S24/25 - Qoba ho kopana le letlalo le mahlo.
S61 - Qoba ho lokolloa tikolohong.Sheba litaelo tse khethehileng / maqephe a tšireletso.
S45 - Ha ho ka etsahala kotsi kapa ha o ikutlwa o sa phele hantle, batla keletso ho ngaka hanghang (bontsha leibole neng kapa neng ha ho kgoneha.)
Li-ID tsa UN UN 2811 6.1 / PGIII

27387-31-1 - Kopo:

1,2,3,9-Tetrahydro-9-Methyl-4H-Carbazole-4-one (CAS: 27387-31-1) e sebelisoa e le bohareng ba Ondansetron Hydrochloride Dihydrate (CAS: 103639-04-9).Nts'etsopele ea k'hamphani ea Glaxo ea United Kingdom, 1990 Fora, 'maraka oa United Kingdom.Sehlahisoa ke mohanyetsi oa serotonin (5-HT3) ea khethiloeng haholo, e ka thibelang ho nyekeloa ke pelo ho bakoang ke chemotherapy le radiotherapy Vomit, ka matla a phahameng le khetho e phahameng, e ka laola mala a manyenyane le li-receptor tsa CTZ tse bakoang ke ho tsosoa ha Mahlatsa.E loketse ho alafa ho nyekeloa ke pelo Mahlatsa a bakoang ke chemotherapy le radiotherapy, hape e ka sebelisoa bakeng sa ho thibela le ho phekola ho nyekeloa ke pelo Mahlatsa a bakoang ke ka mor'a ho buuoa.

Ondansetron, granisetron le dolasetron ke lithethefatsi tse tharo tsa antiemetic tse atisang ho sebelisoa tleliniking, ondansetron ke matla, a khethang le a fetohang 5-hydroxytryptamine (5-HT3) receptor blocker bakeng sa Alpha 1, Alpha 2, beta 1, Beta 2 adrenergic receptors le histamine H1, H2 receptor e na le phello e fokolang, 'me ha e na phello e hanyetsang ho H receptor, central and peripheral dopaminergic receptors,' me e ka thibela ho nyekeloa ke pelo le ho hlatsa ho bakoang ke chemotherapy le radiotherapy.Ha ho bapisoa le metoclopramide, phello ea antiemetic e ne e le matla 'me ho ne ho se na karabelo ea extrapyramidal.Cisplatin, cyclophosphamide, doxorubicin e bakoang ke Vomit e ka hlahisa phello e potlakileng le e matla ea ho thibela ho nyekeloa ke pelo.E loketse bakeng sa phekolo ea lithethefatsi tsa cytotoxic tse bakoang ke chemotherapy le phekolo ea mahlaseli a Ho nyekeloa ke pelo Mahlatsa, empa hape le ho thibela le ho phekola ho nyekeloa ke pelo Mahlatsa a bakoang ke ho buuoa.ondansetron e sebetsa e le setsi sa phetisetso pakeng tsa methapo ea visceral afferent e sebetsang ka har'a pampitšana ea gastrointestinal le Mahlatsa a litsi tsa mokokotlo, tse bakang ho sisinyeha ha mpa le diaphragmatic.Lithethefatsi tsa chemotherapy le phekolo ea mahlaseli li ka baka ho lokolloa ha 5-HT ka maleng a manyenyane, 'me Vomit reflex e bakoa ke ho tsosoa ha methapo ea vagus ka 5-HT3 receptor.Sehlahisoa sena se thibela ho hlaha ha reflex ena, ha se ntse se thibela Mahlatsa a bakoang ke ketso e bohareng.Mokhoa oa ts'ebetso o ne o sa tsejoe bakeng sa Nausea Vomit ka mor'a ho buuoa.Ondansetron e kopantsoe le dexamethasone e ka ntlafatsa phello ea antiemetic.